Sources of Data

Resources

Molecules and How to Visualize Them

OSIRIS DataWarrior (general purpose open-source chemoinformatics software).
Google Sheet of all OSM Compounds (Can filter Series 4).
Sister sheet that explains column headings (i.e. assays used).
Visualisation of OSM molecules on Cheminfo. The data may be visualized with Vortex. The Series 4 SDF can be generated on Cheminfo - here is a downloadable version from May 2016.

Lab Notebooks

The principal Labtrove ELN
Ed Tse's Labarchives ELN
Jasper Tyler's Lab Notebook
Chase Smith's Labarchives ELN
Old document from CRO describing synthetic chemistry of some members of series

Papers

First paper based on this series is being written up here. Relevant 2016 review from MMV. 2017 New developments in anti-malarial target candidate and product profiles

How To Join In

The To Do List
How to involve yourself in OSM is described in the Landing Page under "Join the Team".

Document Archive

Initial briefing document on the series written for MMV and a PDF summary of pharmacokinetics and efficacy; largely folded into the page below. (A minor error in the briefing document referring to the amides has been clarified.)

PDF of the Compounds Originally Inherited from MMV including structures and potencies (http://malaria.ourexperiment.org/osdd_malaria_shared/8106/MMV_triazolopyrazine_data.html older version of this file])

Old Summary of Data on Amides in the Series

ELN post containing many of the raw Chemdraw and picture files for this wiki page - if you generate new pictures, add to the ELN page. This resource needs porting to Github.

Project Reports: Devon Scott and Eduvie Omene, University of Edinburgh, Tom MacDonald, The University of Sydney.

Online Meetings

Most recent online meeting (May 2016) relevant to this series. Recording.

This page is at http://tinyurl.com/OSM-Series4