Potency vs. Resistant Strains
A representative compound from the series (MMV669844 (OSM-S-218)) was evaluated against resistant strains and found to be potent, i.e. no cross-resistance was observed.
Strains examined: Dd2, Dd2 DDD107498, Dd2 FOS-R, Dd2 390048, Dd2 DSM265, Dd2 GNF156, Dd2 ELQ300, NF54, K1, 7G8, TM90C2B, Cam3.I (MRA1240)
Raw data. can also be found here. Relevant GHI.