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polish docs before release
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sigven committed Jun 26, 2024
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2 changes: 1 addition & 1 deletion README.md
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Expand Up @@ -26,7 +26,7 @@ PCGR supports both of the most recent human genome assemblies (grch37/grch38), a

### News

- *June 2024*: **2.x.x release**
- *June 2024*: **2.0.0 release**
- Massive reference data bundle upgrade, new report layout, oncogenicity classification++
- Details at [CHANGELOG](http://sigven.github.io/pcgr/articles/CHANGELOG.html)

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3 changes: 2 additions & 1 deletion pcgrr/vignettes/CHANGELOG.Rmd
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Expand Up @@ -48,7 +48,7 @@ pdiakumis <- user("pdiakumis")

## v2.0.0

* Date: **2024-06-xx**
* Date: **2024-06-26**
* Major data updates
* ClinVar
* NCI Thesaurus
Expand All @@ -73,6 +73,7 @@ pdiakumis <- user("pdiakumis")
- Re-engineered data bundle generation pipeline
- Improved data bundle documentation
- An HTML report with an overview of the contents of the data bundle is shipped with the reference data itself, also available [here (grch38)](https://rpubs.com/sigven/pcgr_refdata).
- Singularity/Apptainer support
- Moved more of the code base to initial Python workflow steps (biomarker matching, CNA segment annotation, RNA expression analysis, oncogenicity classification)
- Variants are now classified with respect to both oncogenicity and actionability, and the previous global tier classification (tier 1-5) is thus deprecated
- New copy number input format - allele-specific (chrom, start, end, n_major, n_minor)
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4 changes: 4 additions & 0 deletions pcgrr/vignettes/installation.Rmd
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Expand Up @@ -255,3 +255,7 @@ apptainer exec \
--tumor_af_tag "TAF" \
--vcf2maf
```

If you run into issues or problems related to apptainer/singularity, we appreciate if you can try to
resolve them directly through the apptainer community. The authors of PCGR/CPSR have limited experience with apptainer, and we thus cannot offer extensive feedback on issues related to such matters.

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