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Main fixsnakemake #17

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Main fixsnakemake #17

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Congm12
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@Congm12 Congm12 commented Dec 10, 2024

  • In case spaceranger outputs contain unzipped barcodes.tsv instead of barcodes.tsv.gz, add a check in calicos.smk to handle both cases.
  • In case the cellsnp-lite and eagle2 outputs contain a large number of SNPs and spots/cells that can't be loaded in a dense matrix, the utils/get_snp_matrix.py code in the preprocessing step is updated to combine eagle2 phasing into cellsnp-lite genotyping using all sparse matrix operations, which eventually outputs eagle2-phased A allele count and B allele count sparse matrices.

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