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@daklab Knowles lab @ NYGC/ColumbiaU

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    12 repositories

    • daklab.github.io

      Public
      Github Pages homepage
      HTML
      •
      Other
      •4•1•0•0•Updated Dec 4, 2024Dec 4, 2024

    • gruyere

      Public
      Genome-wide Rare Variant EnRichment Evaluation
      Python
      •0•0•0•0•Updated Nov 9, 2024Nov 9, 2024

    • LeafletFA

      Public
      A probabilistic factor model for learning RNA splicing driven cell states in single cell RNA-seq data
      Jupyter Notebook
      •
      MIT License
      •0•0•0•0•Updated Nov 4, 2024Nov 4, 2024

    • parmigiano

      Public
      Probabilistic Analysis of Rare variants Modeled In Genome-wIde ANnotation-informed Overdispersion test
      Python
      •0•0•0•0•Updated Oct 27, 2024Oct 27, 2024

    • leafcutter2_testing

      Public
      Annotation-free quantification of RNA splicing. Yang I. Li, David A. Knowles, Jack Humphrey, Alvaro N. Barbeira, Scott P. Dickinson, Hae Kyung Im, Jonathan K. Pritchard
      R
      •
      Apache License 2.0
      •115•0•0•0•Updated Jul 31, 2024Jul 31, 2024

    • poolqtl

      Public
      Jupyter Notebook
      •3•0•0•0•Updated May 29, 2024May 29, 2024

    • LeafletSC

      Public
      Leaflet is a probabilistic model that identifies latent cell states defined by splicing changes.
      Jupyter Notebook
      •
      MIT License
      •1•10•0•0•Updated May 10, 2024May 10, 2024

    • isoviz

      Public
      isoviz is a package that allows for simplified junction to transcript level visualization with Cas13 gRNA design capability.
      HTML
      •
      Other
      •0•4•0•0•Updated Mar 25, 2024Mar 25, 2024

    • variancePartition_leafcutter_extension

      Public
      Quantify and interpret divers of variation in multilevel splicing experiments
      R
      •14•0•0•0•Updated Oct 25, 2023Oct 25, 2023

    • tiger

      Public
      Python
      •
      Other
      •5•11•0•0•Updated Sep 18, 2023Sep 18, 2023

    • seabass

      Public
      Jupyter Notebook
      •
      GNU General Public License v3.0
      •0•0•0•0•Updated Sep 10, 2023Sep 10, 2023

    • MungeSumstats

      Public
      Rapid standardisation and quality control of summary statistics from GWAS
      R
      •15•0•0•0•Updated Sep 17, 2021Sep 17, 2021