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T1K v1.0.4

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@mourisl mourisl released this 07 Oct 16:29
· 35 commits to master since this release

When extracting the reference sequences from the IPD-HLA/KIR database, the new script will keep the partial alleles (partial: either explicitly marked as partial or have missing intron) that have complete exon sequences. The missing intron anchors for those partial alleles will be filled by the most commonly used intron anchor sequences from the same gene.

This may hugely impact the KIR allele predictions as many prevalent alleles, such as KIR3DL3*005, have missing introns but complete exon structures in the IPD-KIR database.