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πŸ₯ a course for clinician scientist (under construction) πŸ‘¨β€βš•οΈ πŸ‘©β€βš•οΈ

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Open Source Society University

πŸ”¬ Path to a free self-taught education in Bioinformatics!

Open Source Society University - Bioinformatics Contribute with OSSU on Patreon

Contents

About

This is a practical path for those of you who want to complete a Bioinformatics course on your own time, for free, with courses from the best universities in the World. The course has been adapted from OSSU Bioinformatics Course, which covers the scientific and mathematicla foundations. However, being a medical student myself, I understand the importance of bioinformatics but anticipate it will be challenging, if not impossible, for any medical student or practising doctors to incorporate a solid four-year part-time curriculum into their schedule. Thus, this curriculum is created in mind with people who need to know the basic science, programming techniques and statistical analysis immediately for their upcoming research projects. Instead of building from ground up, this curriculum is built top down, providing immediate exposure to the daily practice of a bioinformatician. Theories are introduced only later in the curriculum so that one can improve their workflow by understsanding the inner workings of the programmes and statistics.

In our curriculum, we give preference to MOOC (Massive Open Online Course) style courses because these courses were created with our style of learning in mind. I will also give preferences to courses that I have personally taken and considered them as good. However, alternative courses are always welcome.

The course will be designed to be domain-specific. This means courses will be divided into subjects in addition to their level of difficulty. This allows one student to, for example, take the statsitics course solely, because that is all they need to know for their clinical research project.

This curriculum is a pilot test of a clinician-scientist community project. Currently there are communities for programmers, bioinformaticians and doctors, but there is no targeted community for clinician-scientists. As an aspiring clinician-scientist, I hope to build such a community to foster communications and inspirations among like-minded people. This can be a place to for sharing progress, experiences, resources and ideas. If you are interested in joining me to build this project, pleasae do not hesitate to contact me.

This is still a repository under construction. I may hope to migrate this repository to OSSU, but I am not sure if the ideology of this curriculum is the same as theirs - it seems they are trying to emulate an undergraduate curriculum in their organisation, but I am trying to create a bootcamp. I may migrate this curriculum to a Hugo page (currently looking at Syna theme)

Motivation & Preparation

Here are two interesting links that can make all the difference in your journey.

The first one is a motivational video that shows a guy that went through the "MIT Challenge", which consists of learning the entire 4-year MIT curriculum for Computer Science in 1 year.

The second link is a MOOC that will teach you learning techniques used by experts in art, music, literature, math, science, sports, and many other disciplines. These are fundamental abilities to succeed in our journey.

Are you ready to get started?

Curriculum

Basics

This section includes the most basic knowledge that one should know before starting on a journey to become a bioinformatician. This aims to equip you with working knowledge in biology, programming (bash, python and R) and statistics.

Course Duration Effort
Introduction to Biology 12 weeks 7-14 Hours/Week
CS 1 - Python 1 5 Weeks 6 Hours/Week
CS 1 - Python 2 4 Weeks 6 Hours/Week
Introduction to Probability and Data (with R) 5 Weeks 6 Hours/Week
Inferential Statistics (with R) 5 Weeks 6 Hours/Week
The Unix Workbench (first 3 weeks) 3 Weeks 6 Hours/Week
Textbook Duration Effort

UNDER CONSTRUCTION

2nd Year

Code Course Duration Effort
Genomic Data Science Specialization 32 Week 6 Hours/Week

3rd Year

Code Course Duration Effort
BIO 3311 Proteins' Biology 5 Weeks 4-6 Hours/Week
COMP 3311a Algorithmic Thinking 1 4 Weeks 6 Hours/Week
COMP 3311b Algorithmic Thinking 2 4 Weeks 6 Hours/Week
MATH 3311 Linear Regression and Modeling (with R) 4 Weeks 6 Hours/Week
MATH 3312 Bayesian Statistics (with R) 5 Weeks 6 Hours/Week
BIO 3312 Cell Biology - Weeks - Hours/Week
MATH 3313 Differential Equations 7 Weeks 8-10 Hours/Week
BIO 3313a Biostatistics 1 4 Weeks 3-5 Hours/Week
BIO 3313b Biostatistics 2 4 Weeks 3-5 Hours/Week

4th Year

Code Course Duration Effort
BIO 4312d Bioinformatics 1 4 Weeks 4-10 Hours/Week
COMP 4312a Bioinformatics 2 4 Week 6 Hours/Week
COMP 4312b Bioinformatics 3 4 Week 6 Hours/Week
COMP 4312c Bioinformatics 4 4 Week 6 Hours/Week
COMP 4312d Bioinformatics 5 4 Week 6 Hours/Week
COMP 4312e Bioinformatics 6 4 Week 6 Hours/Week
COMP 4312f Bioinformatics 7 (Capstone) 3 Week 3-4 Hours/Week
BIO 4313 Evolution 11 Weeks 4-6 Hours/Week

Extra Year

Code Course Duration Effort
COMP 5311 Introduction to Machine Learning 10 Weeks 6 Hours/Week
COMP 5312 Deep Learning 8 Weeks 6 Hours/Week
Extension

Will continue with Master's in Bioinformatics


keep learning

How to use this guide

Order of the classes

This guide was developed to be consumed in a linear approach. What does this mean? That you should complete one course at a time.

The courses are already in the order that you should complete them. Just start the first course, Introduction to Biology, when you done with it, start the next one.

If the course is not open, do it with the archived resources or wait until next class is open.

How to track and show your progress

  1. Create an account in Trello.
  2. Copy this board to your personal account. See how to copy a board here.

Now that you have a copy of our official board, you just need to pass the cards to the Doing column or Done column as you progress in your study.

We also have labels to help you have more control through the process. The meaning of each of these labels is:

  • Main Curriculum: cards with that label represent courses that are listed in our curriculum.
  • Extra Courses: cards with that label represent courses that was added by the student.
  • Doing: cards with that label represent courses the student is current doing.
  • Done: cards with that label represent courses finished by the student. Those cards should also have the link for at least one project/article built with the knowledge acquired in such course.
  • Section: cards with that label represent the section that we have in our curriculum. Those cards with the Section label are only to help the organization of the Done column. You should put the Course's cards below its respective Section's card.
  • Extra Sections: cards with that label represent sections that was added by the student.

The intention of this board is to provide for our students a way to track their progress, and also the ability to show their progress through a public page for friends, family, employers, etc. You can change the status of your board to be public or private.

Should I take all courses?

Yes! The intention is to conclude all the courses listed here! Also we highly encourage you to complete more by reading papers and attending research projects after your coursework is done.

Duration of the course

It may take longer to complete all of the classes compared to a regular Bioinformatics course, but we can guarantee you that your reward will be proportional to your motivation/dedication!

You must focus on your habit, and forget about goals. Try to invest 1 ~ 2 hours every day studying this curriculum. If you do this, inevitably you'll finish this curriculum.

See more about "Commit to a process, not a goal" here.

Project Based

Here in OSS University, you do not need to take exams, because we are focused on real projects!

In order to show for everyone that you successfully finished a course, you should create a real project or write papers and publish them about your focus with Bioinformatics.

"What does it mean?"

After finish a course, you should think about a real world problem that you can solve using the acquired knowledge in the course. You don't need to create a big project, but you must create something to validate and consolidate your knowledge, and also to show to the world that you are capable to create something useful with the concepts that you learned.

This part needs upgrade:

  • The projects of all students will be listed in this file. Submit your project's information in that file after you conclude it.
  • Research focused projects

Put the OSSU-Bioinformatics badge in the README of your repository! Open Source Society University - Bioinformatics

  • Markdown: [![Open Source Society University - Bioinformatics ](https://img.shields.io/badge/OSSU-bioinformatics-blue.svg)](https://github.com/open-source-society/bioinformatics)
  • HTML: <a href="https://github.com/open-source-society/bioinformatics"><img alt="Open Source Society University - Bioinformatics" src="https://img.shields.io/badge/OSSU-bioinformatics-blue.svg"></a>

You can create this project alone or with other students!

Project Suggestions

  1. (Add Suggestions Here)

And you should also...

Be creative!

This is a crucial part of your journey through all those courses.

You need to have in mind that what you are able to create with the concepts that you learned will be your certificate and this is what really matters!

In order to show that you really learned those things, you need to be creative!

Here are some tips about how you can do that:

  • Articles: create blog posts to synthesize/summarize what you learned.
  • GitHub repository: keep your course's files organized in a GH repository, so in that way other students can use it to study with your annotations.

Cooperative work

We love cooperative work! Use our channels to communicate with other fellows to combine and create new projects!

Which programming languages should I use?

List of skills:

  • C/C++
  • Unix System
  • Python/Perl
  • R
  • Algorithms

These skills mentioned above are the very essential tool set that bioinformatician and computational biologist depends on.

The important thing for each course is to internalize the core concepts and to be able to use them with whatever tool (programming language) that you wish.

Content Policy

You must share only files that you are allowed to! Do NOT disrespect the code of conduct that you signed in the beginning of some courses.

Be creative in order to show your progress! πŸ˜„

Stay tuned

Watch this repository for futures improvements and general information.

Prerequisite

The only things that you need to know are how to use Git and GitHub. Here are some resources to learn about them:

Note: Just pick one of the courses below to learn the basics. You will learn a lot more once you get started!

Change Log

How to collaborate

You can open an issue and give us your suggestions as to how we can improve this guide, or what we can do to improve the learning experience.

You can also fork this project and send a pull request to fix any mistakes that you have found.

TODO: If you want to suggest a new resource, send a pull request adding such resource to the extras section.

The extras section is a place where all of us will be able to submit interesting additional articles, books, courses and specializations, keeping our curriculum as immutable and concise as possible.

Let's do it together! =)

Code of conduct

OSSU's code of conduct.

Community

Subscribe to our newsletter

Use our forum if you need some help.

You can also interact through GitHub issues.

We also have a chat room! Gitter

Add Open Source Society University to your Linkedin and Facebook profile!

ps: A forum is an ideal way to interact with other students as we do not lose important discussions, which usually occur in communication via chat apps. Please use our forum for important discussions.

Next Goals

Team

References

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