You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
Curves fit with fixtop with neutralizing titers outside the bounds of the assay draw curves immediately before the first point (lower bound). This is potentially confusing, since it looks like neutralization is being extrapolated outside the range of dilutions tested in the assay. Curvefits like these are more of a visual issue, since these data and the inferred curves call NT50s as being on the upper or lower bounds, which is the correct quantitative behavior. Example below:
These curves were inferred with fixtop = [0.75,1] and fixslope = [0.8,10]. The bottoms of curves are default fixed to 0. Corresponding curvefits and the raw fractional infectivity values: frac_infectivity.csv curvefits.csv
The text was updated successfully, but these errors were encountered:
Curves fit with fixtop with neutralizing titers outside the bounds of the assay draw curves immediately before the first point (lower bound). This is potentially confusing, since it looks like neutralization is being extrapolated outside the range of dilutions tested in the assay. Curvefits like these are more of a visual issue, since these data and the inferred curves call NT50s as being on the upper or lower bounds, which is the correct quantitative behavior. Example below:
These curves were inferred with
fixtop = [0.75,1]
andfixslope = [0.8,10]
. The bottoms of curves are default fixed to 0. Corresponding curvefits and the raw fractional infectivity values:frac_infectivity.csv
curvefits.csv
The text was updated successfully, but these errors were encountered: