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Welcome to the GLUE User Guide!
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GLUE (Genes Linked by Underlying Evolution) is an open, integrated software toolkit implemented in Java™. It is designed to facilitate the storage, management, and analysis of sequence data, offering researchers a powerful platform for genomic investigations.
GLUE provides a framework for the development of sequence data-oriented 'projects' that focus on specific genome features or small genomes (e.g., viral genomes). These projects encompass the data items necessary for conducting comparative genomics investigations, including sequences, genome feature annotations, alignments, phylogenies, and any other relevant data.
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Stored virus nucleotide sequences are organized along evolutionary lines.
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Common bioinformatics operations are supported as standard.
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The data schema and bioinformatics functionality can be customized and extended.
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Data and functionality can be quickly developed offline, then published as part of a web service.
GLUE provides a standardized yet customizable platform for genomic analyses. It enhances collaboration within research teams, supports reproducibility in analyses, and enables integration with existing bioinformatics workflows. Whether you're working on comparative genomics, phylogenetic analysis, or custom data processing, GLUE offers the tools necessary to streamline your research.
This user guide is designed to help you navigate GLUE's features, from basic commands to advanced scripting. You'll find detailed documentation on core functionalities, module usage, and examples of common workflows. As you explore GLUE, we encourage you to leverage the resources available in this guide to enhance your research capabilities.
For more information, please visit the GLUE website: http://tools.glue.cvr.ac.uk.
Join us in advancing genomic research with GLUE!
GLUE by Robert J. Gifford Lab.
For questions, issues, or feedback, please open an issue on the GitHub repository.
- Project Data Model
- Schema Extensions
- Modules
- Alignments
- Variations
- Scripting Layer
- Freemarker Templates
- Example GLUE Project
- Command Line Interpreter
- Build Your Own Project
- Querying the GLUE Database
- Working With Deep Sequencing Data
- Invoking GLUE as a Unix Command
- Known Issues and Fixes
- Overview
- Hepatitis Viruses
- Arboviruses
- Respiratory Viruses
- Animal Viruses
- Spillover Viruses
- Virus Diversity
- Retroviruses
- Paleovirology
- Transposons
- Host Genes