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Update tutorial.md
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katherine-d21 authored Dec 11, 2023
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# Reducing Database size
## Sub-step with **MetaNovo**
Next, the large comprehensive database of ~2.59 million sequences can be reduced using the MetaNovo tool to generate a more manageable database that contains identified proteins. The compact MetaNovo-generated database (~1.9K sequences) will be merged with Human SwissProt (reviewed only) and contaminants (cRAP) databases to generate the reduced database (~21.2k protein sequences) that will be used for peptide identification **(cite Discovery module tutorial)**.
Next, the large comprehensive database of ~2.59 million sequences can be reduced using the MetaNovo tool to generate a more manageable database that contains identified proteins. The compact MetaNovo-generated database (~1.9K sequences) will be merged with Human SwissProt (reviewed only) and contaminants (cRAP) databases to generate the reduced database (~21.2k protein sequences) that will be used for peptide identification (see [Discovery Module tutorial](https://github.com/subinamehta/training-material/blob/main/topics/proteomics/tutorials/clinical-mp-discovery/tutorial.md)).
> <hands-on-title> Metanovo tool generates a compact database from your comprehensive database. </hands-on-title>
>
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