How to confirm the global polar amino acid bias value? What is the meaning of 1.39?

[luojc712]

In the example 8 script,
path_for_bias=$output_dir"/bias_pdbs.jsonl"
#Adding global polar amino acid bias (Doug Tischer)
AA_list="D E H K N Q R S T W Y"
bias_list="1.39 1.39 1.39 1.39 1.39 1.39 1.39 1.39 1.39 1.39 1.39"
python ../helper_scripts/make_bias_AA.py --output_path=$path_for_bias --AA_list="$AA_list" --bias_list="$bias_list"
I want to know what is the meaning of "1.39", and how to decide the number?

[Saddy48]

Even I have the same doubt. Is there a formula to calculate these biases? If so then can you please share the formula?

[johnnytam100]

Hi same question on the physical meaning of 1.39.