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ALWAYS UPDATE TO LATEST KERNEL AND THEN GO FOR ARCH SPECIFIC INSTALL.
For Virtualbox:
After updating kernel,
dpkg --remove-architecture i386
apt-get purge virtualbox
apt-get remove virtualbox
reboot
Download your .deb file from Website
gdebi virtualbox-*.deb
/etc/init.d/vboxdrv setup
For Wine: Straight up install from apt-get after Kernel update.