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FL.2.2 (XBB.1.9.1.2.2) sublineage with S:T307I (84 seqs in 8 countries) #2027

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HynnSpylor opened this issue May 30, 2023 · 4 comments
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@HynnSpylor
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Defining mutations: FL.2.2>C22482T (S:T307I)
GISAID query: Spike_T478R, Spike_T307I, T4579A, G5720A
Earliest seq: 2023-03-03 (Indonesia EPI_ISL_17324400)
Most recent seq: 2023-05-22 (Singapore, EPI_ISL_17724805)
Countries detected: Indonesia (59), Singapore (10), South Korea (7), Australia (3), Japan (2), China (1, from Taiwan Region), USA (1), Thailand (1)

Usher Tree:
QQ截图20230530215255

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_271e8_5fdca0.json

@FedeGueli has mentioned the FL.2.2 sublineage with lots of S:T307I samples in #1927. Hence I'm just making a supplement.

Note that 84 of 113 FL.2.2 samples (via GISAID query) get S:T307I. 7 of 84 further get S:Q675L.

Genomes:
EPI_ISL_17324400, EPI_ISL_17372734, EPI_ISL_17372736, EPI_ISL_17412584, EPI_ISL_17432027, EPI_ISL_17465903, EPI_ISL_17468574, EPI_ISL_17496051, EPI_ISL_17518055, EPI_ISL_17518064, EPI_ISL_17518067, EPI_ISL_17518074, EPI_ISL_17546399, EPI_ISL_17546427, EPI_ISL_17546465, EPI_ISL_17551391, EPI_ISL_17551407, EPI_ISL_17551455, EPI_ISL_17551483, EPI_ISL_17551511, EPI_ISL_17551549,
EPI_ISL_17605938, EPI_ISL_17606085-17606086, EPI_ISL_17622326, EPI_ISL_17622334, EPI_ISL_17622345, EPI_ISL_17622357,
EPI_ISL_17623745, EPI_ISL_17623759, EPI_ISL_17624266, EPI_ISL_17630002, EPI_ISL_17631100, EPI_ISL_17655965, EPI_ISL_17661252, EPI_ISL_17670171, EPI_ISL_17670314, EPI_ISL_17677501, EPI_ISL_17681175, EPI_ISL_17681237, EPI_ISL_17681250,
EPI_ISL_17681280-17681281, EPI_ISL_17681313, EPI_ISL_17681320, EPI_ISL_17681364, EPI_ISL_17681400-17681401, EPI_ISL_17681403, EPI_ISL_17681405, EPI_ISL_17681443, EPI_ISL_17681451, EPI_ISL_17681454, EPI_ISL_17681485, EPI_ISL_17681492, EPI_ISL_17681539, EPI_ISL_17686521, EPI_ISL_17686525, EPI_ISL_17686585, EPI_ISL_17686594, EPI_ISL_17691549, EPI_ISL_17694970, EPI_ISL_17696443,
EPI_ISL_17696453, EPI_ISL_17696711, EPI_ISL_17709540, EPI_ISL_17717569, EPI_ISL_17717575, EPI_ISL_17719480-17719481,
EPI_ISL_17719492, EPI_ISL_17719500, EPI_ISL_17719502, EPI_ISL_17719560, EPI_ISL_17719593, EPI_ISL_17719601, EPI_ISL_17723138, EPI_ISL_17723376, EPI_ISL_17723634, EPI_ISL_17724802-17724803, EPI_ISL_17724805-17724807

@FedeGueli
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FedeGueli commented May 30, 2023

Thx Hynn the branch growing in FL.2.2 is the one with S:T307I but good to highlight that with its own lineage.
While 675L seems interesting doing the FCS + Flanking mutations: SYLTQTKSHRRARSVASQ

@FedeGueli
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Designated FL.2.2.1 via 6a1de6c

@FedeGueli
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Fast Query: C22482T , T4579A, G5720A

@FedeGueli
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Pls close this one

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