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Marginal gain of gene expression data over covariates #67

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Feb 13, 2017
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383fb0e
Work on TP53 mutation prediction from metadata
joshlevy89 Oct 26, 2016
66ce66a
Work on comparison of covariates only model to covariates with gene e…
joshlevy89 Nov 1, 2016
ab39b4d
Fixed output display for a cell block.
joshlevy89 Nov 1, 2016
1b46c9e
Removed space in file name
joshlevy89 Nov 1, 2016
058075e
Converted notebook to script.
joshlevy89 Nov 1, 2016
70c0638
Work on extending covariates only to covariates with expression model…
joshlevy89 Nov 2, 2016
a649bb2
Changed alpha/il_ratio params for grid search.
joshlevy89 Nov 4, 2016
893ed83
Created different pipelines for covariates and combined model (covari…
joshlevy89 Nov 5, 2016
927d3a2
Added alternative pipeline for combined model using DataFrameMapper.
joshlevy89 Nov 5, 2016
60b099b
Work on fixing pipeline and naming conventions.
joshlevy89 Nov 5, 2016
04575d3
Work on consolidating example notebook into multiple mutation noteboo…
joshlevy89 Nov 6, 2016
a25e75d
Ran comparison with complete model and hyperparamters.
joshlevy89 Nov 6, 2016
2ea19f0
Re-converted to script.
joshlevy89 Nov 6, 2016
214f83a
Re-saved auroc dfs
joshlevy89 Nov 6, 2016
c4a1979
.DS_Store banished!
joshlevy89 Nov 8, 2016
cc3d9f5
Removed duplicate notebook
joshlevy89 Nov 8, 2016
d4b45ff
Combined auroc dataframes for each model into one model and saved as …
joshlevy89 Nov 8, 2016
d800c9e
Work on training/testing approach for both models.
joshlevy89 Nov 8, 2016
2c19919
Fixed format of writing to csv. Updated script with notebook changes.
joshlevy89 Nov 8, 2016
82e6fd2
Moved script.
joshlevy89 Nov 8, 2016
565a1b0
Ran models with most recent config.
joshlevy89 Nov 9, 2016
57fff61
Converted to script for most recent notebook.
joshlevy89 Nov 9, 2016
fa5e92e
Ran simplified analysis for covariates only.
joshlevy89 Nov 16, 2016
2311231
Ran for just ALK.
joshlevy89 Nov 16, 2016
ab87b9d
Continued to make more similar to confounding and acheived reasonable…
joshlevy89 Nov 16, 2016
589b1cd
Changed parameters to match prior covariates results.
joshlevy89 Nov 16, 2016
2271026
Ran both models with lots of params.
joshlevy89 Nov 17, 2016
2534792
Simplified the comparison for RET
joshlevy89 Nov 22, 2016
48b8803
Removed grid search
joshlevy89 Nov 22, 2016
f8a55e0
Changed notebook names
joshlevy89 Nov 22, 2016
9d51483
Added alpha .1 Ret comparison
joshlevy89 Nov 22, 2016
43838f6
Converted to py scripts
joshlevy89 Nov 22, 2016
8a0cc68
Added complete ridge regression run.
joshlevy89 Dec 19, 2016
3571ca6
Added marginal gain example for Ret
joshlevy89 Jan 13, 2017
b6979b8
Cleaned up unused files
joshlevy89 Jan 13, 2017
059b188
Extending to multiple genes and added some more viz
joshlevy89 Jan 13, 2017
0477f38
small change
joshlevy89 Jan 13, 2017
6c5eee6
Reoganized helper functions
joshlevy89 Jan 14, 2017
ae585ce
Improved viz for multiple genes, gene categories
joshlevy89 Jan 14, 2017
8c5b6f5
Cleaned up plotting
joshlevy89 Jan 14, 2017
2ec415b
Ran all updated notebooks.
joshlevy89 Jan 14, 2017
5fa96ad
Ran ret example.
joshlevy89 Jan 15, 2017
ef02525
Scaled before pca and re-ran
joshlevy89 Jan 15, 2017
bb55140
Added variance explained calculation.
joshlevy89 Jan 15, 2017
f7c776a
Fixed heatmap on ret example.
joshlevy89 Jan 15, 2017
1a8282c
Converted notebooks to scripts
joshlevy89 Jan 15, 2017
fc7d35f
Update master from simplified branch.
joshlevy89 Jan 15, 2017
f5e754a
Fixed plot labels
joshlevy89 Jan 15, 2017
823a527
Converted nbs to scripts.
joshlevy89 Jan 15, 2017
9cc705d
Applied PR changes.
joshlevy89 Jan 22, 2017
464a88b
Re-ran download and script.
joshlevy89 Jan 22, 2017
d5ef04f
Converted pca notebook to script
joshlevy89 Jan 22, 2017
0b7addf
Applied pr changes to mad nb
joshlevy89 Feb 13, 2017
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3 changes: 3 additions & 0 deletions .gitignore
Original file line number Diff line number Diff line change
Expand Up @@ -4,6 +4,9 @@
# Large downloaded data files
download/

# Mac metadata
.DS_Store

# Python
__pycache__/
*.egg-info/
12 changes: 7 additions & 5 deletions 1.download.ipynb
Original file line number Diff line number Diff line change
Expand Up @@ -59,7 +59,7 @@
{
"data": {
"text/plain": [
"'10.6084/m9.figshare.3487685.v5'"
"'10.6084/m9.figshare.3487685.v6'"
]
},
"execution_count": 4,
Expand Down Expand Up @@ -96,10 +96,12 @@
"name": "stdout",
"output_type": "stream",
"text": [
"Downloading https://ndownloader.figshare.com/files/5864859 to `expression-matrix.tsv.bz2`\n",
"Downloading https://ndownloader.figshare.com/files/5864862 to `mutation-matrix.tsv.bz2`\n",
"Downloading https://ndownloader.figshare.com/files/6207135 to `samples.tsv`\n",
"Downloading https://ndownloader.figshare.com/files/6207138 to `covariates.tsv`\n"
"Downloading https://ndownloader.figshare.com/files/7311959 to `samples.tsv`\n",
"Downloading https://ndownloader.figshare.com/files/7311956 to `covariates.tsv`\n",
"Downloading https://ndownloader.figshare.com/files/7311950 to `expression-matrix.tsv.bz2`\n",
"Downloading https://ndownloader.figshare.com/files/7311962 to `expression-genes.tsv`\n",
"Downloading https://ndownloader.figshare.com/files/7311953 to `mutation-matrix.tsv.bz2`\n",
"Downloading https://ndownloader.figshare.com/files/7311965 to `mutation-genes.tsv`\n"
]
}
],
Expand Down
2 changes: 1 addition & 1 deletion explore/confounding/confounding.ipynb
Original file line number Diff line number Diff line change
Expand Up @@ -668,7 +668,7 @@
"metadata": {
"anaconda-cloud": {},
"kernelspec": {
"display_name": "Python [default]",
"display_name": "Python 3",
"language": "python",
"name": "python3"
},
Expand Down
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