4.2.4.0 the log4shell edition
Download release: gatk-4.2.4.0.zip
Docker image: https://hub.docker.com/r/broadinstitute/gatk/
Highlights of the 4.2.4.0 release:
- Fix a major security bug due to log4j vulnerability. (CVE-2021-44228)
- Improvement to calculation of ExcessHet in joint genotyping. (GenotypeGVCFs, GnarlyGenotyper, ExcessHet).
Full list of changes:
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Funcotator
- Aligned the Funcotator checkIfAlreadyAnnotated test with the Funcotator engine code. (#7555)
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GenotypeGVCFs / ExcessHet
- Removed undocumented mid-p correction to p-values in exact test of Hardy-Weinberg equilibrium and updated corresponding tests. We now report the same value as ExcHet in bcftools. Note that previous values of 3.0103 (corresponding to mid-p values of 0.5) will now be 0.0000. (#7394)
- Updated expected ExcessHet values in integration test resources and added an update toggle to GnarlyGenotyperIntegrationTest.
- Updated ExcessHet documentation.
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Miscellaneous Changes
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Documentation
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Dependencies
- Updated log4j to version 2.13.1 -> 2.16.0 to patch CVE-2021-44228 (#7605)