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Supporting materials for Akhmetzhanov AR, Kim JW, Sullivan R, Beckman RA, Tamayo P, Yeang CH 2019 "Modelling bistable tumour population dynamics to design effective treatment strategies." Journal of Theoretical Biology

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AkhmKim2019Scripts

Supporting materials for Akhmetzhanov AR, Kim JW, Sullivan R, Beckman RA, Tamayo P, Yeang CH 2019 "Modelling bistable tumour population dynamics to design effective treatment strategies." J Theor Biol doi:10.1016/j.jtbi.2019.05.005


The code scripts can be viewed in sequential order.

Main part of the analysis with generating most of the figures

Whereas, three variations for different values of the cost of resistance:

Sensitivity analysis:

Construction of the field of optimal trajectories:

Lastly, generation of last two figures (possibly the naming is incorrect):


Written by Andrei R. Akhmetzhanov 2019

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Supporting materials for Akhmetzhanov AR, Kim JW, Sullivan R, Beckman RA, Tamayo P, Yeang CH 2019 "Modelling bistable tumour population dynamics to design effective treatment strategies." Journal of Theoretical Biology

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