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X3N1A authored Aug 2, 2024
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Expand Up @@ -33,10 +33,11 @@ Exemplary epiction of ENT3C derivation of the entropy signal $\mathbf{S}$ of two


# Requirements
Julia or MATLAB
Julia or MATLAB.

* dependencies, packages and version information for julia implementation are defined in ```Project.toml``` and ```Manifest.toml```
* set ```--install-deps=yes``` if you wish to automatically install the packages and resolve environment
* For the Julia implementation, ubuntu's hdf5-tools is also required.

# Data
Both Julia and MATLAB implementations (```ENT3C.jl``` and ```ENT3C.m```) were tested on Hi-C and micro-C contact matrices binned at 40 kb in ```cool``` format.
Expand Down Expand Up @@ -110,9 +111,9 @@ $\dots$ input files in format: ```[<COOL_FILENAME>, <SHORT_NAME>]```

```"Resolution": "40e3,100e3"``` $\dots$ resolutions to be evaluated.

```"ChrNr": "15:22"``` $\dots$ chromosome numbers to be evaluated. Set individual chromosomes as ```ChrNr: "15,17,22"```.
```"ChrNr": "15,16,17,18,19,20,21,22,X"``` $\dots$ chromosome numbers to be evaluated.

```"NormM": 0``` $\dots$ input contact matrices can be balanced. If ```NormM: 1```, balancing weights in cooler are applied.
```"NormM": 0``` $\dots$ input contact matrices can be balanced. If ```NormM: 1```, balancing weights in cooler are applied. If set to 1, ENT3C expects weights to be in dataset ```/resolutions/<resolution>/bins/weight```.

```"SUB_M_SIZE_FIX": null``` $\dots$ fixed submatrix dimension.

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