Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Add documentation for applications of Casanovo #418

Merged
merged 6 commits into from
Dec 16, 2024
Merged
Show file tree
Hide file tree
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
13 changes: 13 additions & 0 deletions docs/applications.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,13 @@
# Applications of Casanovo

_De novo_ peptide sequencing has diverse applications in proteomics, ranging from antibody sequencing to paleoproteomics.
You can find some papers that use Casanovo for _de novo_ sequencing in different domains below.
Contact us with your applications of Casanovo to feature your research on this page by opening a Github issue [here](https://github.com/Noble-Lab/casanovo/issues/new) with a link to the paper and a one-sentence description of how Casanovo is being used.

- **[Comprehensive evaluation of peptide _de novo_ sequencing tools for monoclonal antibody assembly (Beslic et al., *Briefings in Bioinformatics*, 2023)](https://doi.org/10.1093/bib/bbac542)**: Casanovo is used to _de novo_ sequence monoclonal antibodies and shown to outperform other _de novo_ sequencing tools.
- **[Giant genes are rare but implicated in cell wall degradation by predatory bacteria (West-Roberts et al., *bioRxiv*, 2023)](https://doi.org/10.1101/2023.11.21.568195)**: Casanovo is used to _de novo_ sequence giant proteins with up to 85,804 amino acids in a metagenomic setting.
- **[Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic (Bassett et al., *bioRxiv*, 2024)](https://doi.org/10.1101/2024.12.04.626857)**: Casanovo is used to _de novo_ sequence fibrils, i.e. antibody light chain aggregates.
- **[_De novo_ assembled databases enable species-specific protein-based stable isotope probing of microbiomes without prior knowledge of the community composition (Klaes et al., *bioRxiv*, 2024)](https://doi.org/10.1101/2024.11.25.625156)**: Casanovo is used to _de novo_ sequence microbial peptides to enable species-specific protein-based stable isotope probing.
- **[Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases (Chernigovskaya et al., *bioRxiv*, 2024)](https://doi.org/10.1101/2024.11.11.622451)**: Casanovo is used to profile the sequence diversity of circulating monoclonal antibody repertoire.

Last updated on December 14, 2024.
1 change: 1 addition & 0 deletions docs/index.md
Original file line number Diff line number Diff line change
Expand Up @@ -23,6 +23,7 @@ Getting Started <getting_started.md>
File Formats <file_formats.md>
Nextflow Workflow <nextflow.md>
FAQs <faq.md>
Applications <applications.md>
Citing <cite.md>
Contributing <CONTRIBUTING.md>
Code of Conduct <CODE_OF_CONDUCT.md>
Expand Down
Loading