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Correction of the classfication of mono-exons #303

Merged
merged 3 commits into from
May 30, 2024
Merged

Correction of the classfication of mono-exons #303

merged 3 commits into from
May 30, 2024

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alexpan00
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Previously, mono-exons, not classified as FSM or ISM, and contained inside a transcript, were classified as NIC. Now, only those mono-exons spaning a whole intron of the transcript are considered NIC (by intron retention), otherwise, they are considered genic. On the other hand, mono-exons starting before the beginning or ending after the end of the reference transcript were classified as genic, even if they span a whole intron. Now, these transcripts that start/finish before/after the reference transcript and span a whole intron are classified as NIC.

While doing this I found a bug in the classification of ISM mono-exons (probably affecting a very limited number of transcripts). This has also been fixed.

@alexpan00 alexpan00 merged commit a7c2680 into master May 30, 2024
@alexpan00 alexpan00 deleted the genic_nic branch May 30, 2024 12:10
pabloati pushed a commit that referenced this pull request Dec 16, 2024
Correction of the classfication of mono-exons
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