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condition or disease under study #11

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linikujp opened this issue May 16, 2020 · 2 comments
Open

condition or disease under study #11

linikujp opened this issue May 16, 2020 · 2 comments

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@linikujp
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linikujp commented May 16, 2020

Current hierarchy is wrong.

image

The label of this term is from ClinicalTrials.gov http://prsinfo.clinicaltrials.gov/definitions.html#Conditions
And WHO cross reference term is "Health condition(s) or problem(s) studied"

  • ClinicalTrials.gov definition or scope of the term is
    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study *
    Definition: The name(s) of the disease(s) or condition(s) studied in the clinical study, or the focus of the clinical study. (ClinicalTrials.gov recommends using Mesh term or SNOMED CT terms)

  • WHO term and definition
    Health condition(s) or problem(s) studied
    Definition: Primary health condition(s) or problem(s) studied (e.g., depression, breast cancer,
    medication error). If the study is conducted in healthy human volunteers belonging to the
    target population of the intervention (e.g. preventive or screening interventions), enter the particular health condition(s) or problem(s) being prevented.
    (WHO recommends to use controlled vocabulary or free text for those conditions)

This need a term that covers all conditions, disease or any other aspect of health behaviour as the study focus for a clinical trial.

However, the condition here is not a information entity. As BFO and OBI render disease as a disposition, I think we should put this term under the disposition. Label and definition of this term needs improve.
image

@linikujp
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Also, suggest to delete the term of 'study condition'. Below is current arrangement in CTO.
image
However, the condition maybe a synonym of the disease.
And as we don't know what Clinical Trials are all study for. We could text mining what is being studies in ClinicalTrials by tagging them use standardized terminology or ontology, we might get an idea of the scope. I would even suggest to delete this term for now.

@linikujp
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On ClinicalTrials.gov website' search page, it defines the 'condition or disease' as 'The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.'

Terms such as lifespan , quality of life and health risks can not be put under one bucket in all current OBO Foundry ontologies.

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