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Update GSEA docu #133

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Update GSEA docu #133

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Expand Up @@ -35,6 +35,13 @@ For further information visit [GSEA publication](https://academic.oup.com/bioinf


##Method

Note: There are several methods that are summarized under enrichment analysis. The proposed method makes use of the
hypergeometric distribution. The results are *identical* when using a one sided Fishers' exact test.
Another method is to rank a list of bioitems according to a pvalue or effect size and afterwards test the ranks of
every ontology term using e.g. a Kolmogorov-Smirnov test. The latter version is not covered in this documentation.


Imagine an experiment, in which 1000 proteins were measured. Within these 1000 proteins there are 25 proteins
of a specific functional group (heat shock response).
By treating the organism(s) 200 proteins are significantly altered. 10 of the 25 heat responsive proteins
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