PCR-bias

The repository contains the scripts used in the study "Deep learning uncovers sequence-specific amplification bias in multi-template PCR".

CluMo.py

The script includes the motif discovery approach proposed in the study.

InternalValidation.py

Perform 5-fold nested internal validation on the selected dataset.

ExternalValidation.py

Perform external validation on the selected source -> target datasets.

analysis/

Data analysis and plotting for figures in the manuscript.