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grst committed Jan 19, 2024
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2 changes: 1 addition & 1 deletion DESCRIPTION
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Package: MAEio
Package: PersonalisIO
Title: Read Various Data Sources into MultiAssayExperiment objects
Version: 0.1.9000
Authors@R:
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2 changes: 1 addition & 1 deletion README.md
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# Personalis-io
# PersonalisIO

**This package provides convenience functions for reading real-world evidence data provided by [Personalis](https://www.personalis.com/)
into Bioconductor [MultiAssayExperiment](https://bioconductor.org/packages/release/bioc/html/MultiAssayExperiment.html) objects**
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4 changes: 2 additions & 2 deletions tests/testthat.R
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# * https://testthat.r-lib.org/reference/test_package.html#special-files

library(testthat)
library(MAEio)
library(PersonalisIO)

test_check("MAEio")
test_check("PersonalisIO")
12 changes: 6 additions & 6 deletions vignettes/personalis.Rmd
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Expand Up @@ -14,20 +14,20 @@ knitr::opts_chunk$set(
)
```

This vignette demonstrates how to use the {Personalis-io} package to load Personalis
This vignette demonstrates how to use the {PersonalisIO} package to load Personalis
data into a {MultiAssayExperiment} object.

```{r setup}
suppressPackageStartupMessages({
library(MAEio)
library(PersonalisIO)
library(purrr)
library(conflicted)
conflicts_prefer(base::setdiff)
})
```

Personalis ship their data in a (more or less) standardized directory structure
within one folder for each patient. The MAEio loader functions traverse this directory
within one folder for each patient. The PersonalisIO loader functions traverse this directory
structure and extract the different modalities. To load data from multiple patients
into a single object, we need a list of patient directories:

Expand All @@ -45,10 +45,10 @@ We can now read a single modality into a {SummarizedExperiment}. For instance, t
only.

```{r}
personalis_gex <- MAEio::read_personalis_gene_expression(sample_list)
personalis_gex <- PersonalisIO::read_personalis_gene_expression(sample_list)
```

By inspecting the object, we can see, this imported gene expression data from 20 patients and ~23k genes.
By inspecting the object, we can see, this imported gene expression data from 5 patients and ~23k genes.
There are three different assays: `counts`, `tpm` and `normCounts`:

```{r}
Expand All @@ -75,7 +75,7 @@ It is your repsonsibility to check the warnings carefully to make sure that
all data that you expect to be there is successfully imported.

```{r}
mae <- MAEio::read_personalis(sample_list)
mae <- PersonalisIO::read_personalis(sample_list)
```

Here's an overview of the {MultiAssayExperiment} object with all available
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