diff --git a/Marlin/src/HAL/STM32F1/HAL.h b/Marlin/src/HAL/STM32F1/HAL.h
index f4ec3e62dd36c..17001399e8b5b 100644
--- a/Marlin/src/HAL/STM32F1/HAL.h
+++ b/Marlin/src/HAL/STM32F1/HAL.h
@@ -109,6 +109,8 @@
   #else
     #error "LCD_SERIAL_PORT must be -1 or from 1 to 3. Please update your configuration."
   #endif
+
+  #define SERIAL_GET_TX_BUFFER_FREE LCD_SERIAL.availableForWrite
 #endif
 
 // Set interrupt grouping for this MCU
diff --git a/Marlin/src/pins/pins.h b/Marlin/src/pins/pins.h
index 10726b3b4112e..7344cd585a62a 100644
--- a/Marlin/src/pins/pins.h
+++ b/Marlin/src/pins/pins.h
@@ -576,6 +576,8 @@
   #include "stm32f1/pins_CREALITY_V4.h"         // STM32F1                                env:STM32F103RET6_creality
 #elif MB(CREALITY_V427)
   #include "stm32f1/pins_CREALITY_V427.h"       // STM32F1                                env:STM32F103RET6_creality
+#elif MB(CREALITY_V452)
+  #include "stm32f1/pins_CREALITY_V452.h"       // STM32F1                                env:STM32F103RET6_creality
 #elif MB(TRIGORILLA_PRO)
   #include "stm32f1/pins_TRIGORILLA_PRO.h"      // STM32F1                                env:trigorilla_pro
 #elif MB(FLY_MINI)
diff --git a/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h b/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h
new file mode 100644
index 0000000000000..348ab28dff2cf
--- /dev/null
+++ b/Marlin/src/pins/stm32f1/pins_CREALITY_V452.h
@@ -0,0 +1,113 @@
+/**
+ * Marlin 3D Printer Firmware
+ * Copyright (C) 2020 MarlinFirmware [https://github.com/MarlinFirmware/Marlin]
+ *
+ * Based on Sprinter and grbl.
+ * Copyright (C) 2011 Camiel Gubbels / Erik van der Zalm
+ *
+ * This program is free software: you can redistribute it and/or modify
+ * it under the terms of the GNU General Public License as published by
+ * the Free Software Foundation, either version 3 of the License, or
+ * (at your option) any later version.
+ *
+ * This program is distributed in the hope that it will be useful,
+ * but WITHOUT ANY WARRANTY; without even the implied warranty of
+ * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+ * GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with this program.  If not, see <http://www.gnu.org/licenses/>.
+ *
+ */
+
+/**
+ * Creality v4.5.2 (STM32F103RET6) board pin assignments
+ */
+
+#if NOT_TARGET(__STM32F1__)
+  #error "Oops! Select an STM32F1 board in 'Tools > Board.'"
+#elif HOTENDS > 1 || E_STEPPERS > 1
+  #error "CREALITY_V452 supports up to 1 hotends / E-steppers. Comment out this line to continue."
+#endif
+
+#define BOARD_NAME "Creality v4.5.2"
+#define DEFAULT_MACHINE_NAME "Creality3D"
+
+#define BOARD_NO_NATIVE_USB
+
+//
+// EEPROM
+//
+#if NO_EEPROM_SELECTED
+  #define IIC_BL24CXX_EEPROM                    // EEPROM on I2C-0
+  //#define SDCARD_EEPROM_EMULATION
+#endif
+
+#if ENABLED(IIC_BL24CXX_EEPROM)
+  #define IIC_EEPROM_SDA                  PA11
+  #define IIC_EEPROM_SCL                  PA12
+  #define MARLIN_EEPROM_SIZE             0x800  // 2Kb (24C16)
+#elif ENABLED(SDCARD_EEPROM_EMULATION)
+  #define MARLIN_EEPROM_SIZE             0x800  // 2Kb
+#endif
+
+//
+// Limit Switches
+//
+#define X_MIN_PIN           PC4
+// #define X_MAX_PIN          PA7
+#define Y_MIN_PIN           PC5
+#define Z_MIN_PIN           PA4
+#define PROBE_TARE_PIN      PA5
+
+//
+// Steppers
+//
+#define X_ENABLE_PIN        PC3
+#define X_STEP_PIN          PB8
+#define X_DIR_PIN           PB7
+
+#define Y_ENABLE_PIN        PC3
+#define Y_STEP_PIN          PB6
+#define Y_DIR_PIN           PB5
+
+#define Z_ENABLE_PIN        PC3
+#define Z_STEP_PIN          PB4
+#define Z_DIR_PIN           PB3
+
+#define E0_ENABLE_PIN       PC3
+#define E0_STEP_PIN         PC2
+#define E0_DIR_PIN          PB9
+
+
+//
+// Release PB4 (Z_STEP_PIN) from JTAG NRST role
+//
+#define DISABLE_DEBUG
+
+//
+// Temperature Sensors
+//
+#define TEMP_0_PIN         PB1   // TH1
+#define TEMP_BED_PIN       PB0   // TB1
+
+//
+// Heaters / Fans
+
+#define HEATER_0_PIN       PA1   // HEATER1
+#define HEATER_BED_PIN     PA2   // HOT BED
+
+#define FAN_PIN            PA0   // FAN
+#define FAN_SOFT_PWM
+
+/* SD card detect */
+#define SD_DETECT_PIN      PC7
+#define NO_SD_HOST_DRIVE       // SD is only seen by the printer
+
+#define SDIO_SUPPORT           // Extra added by Creality
+#define SDIO_CLOCK     6000000 // In original source code overridden by Creality in sdio.h
+
+#define CASE_LIGHT_PIN     PA6
+
+#define FIL_RUNOUT_PIN     PA7
+#define PROBE_ENABLE_PIN   PC6 // Optoswitch to Enable Z Probe