diff --git a/pkg/mock/mockcluster/mockcluster.go b/pkg/mock/mockcluster/mockcluster.go
index a7edda7c660..122afa872be 100644
--- a/pkg/mock/mockcluster/mockcluster.go
+++ b/pkg/mock/mockcluster/mockcluster.go
@@ -352,6 +352,14 @@ func (mc *Cluster) AddLightWeightLeaderRegion(regionID uint64, leaderStoreID uin
 	return region
 }
 
+// AddNoLeaderRegion adds region with specified replicas, no leader.
+func (mc *Cluster) AddNoLeaderRegion(regionID uint64, otherPeerStoreIDs ...uint64) *core.RegionInfo {
+	origin := mc.newMockRegionInfo(regionID, 0, otherPeerStoreIDs...)
+	region := origin.Clone(core.SetApproximateSize(defaultRegionSize/units.MiB), core.SetApproximateKeys(10))
+	mc.PutRegion(region)
+	return region
+}
+
 // AddRegionWithLearner adds region with specified leader, followers and learners.
 func (mc *Cluster) AddRegionWithLearner(regionID uint64, leaderStoreID uint64, followerStoreIDs, learnerStoreIDs []uint64) *core.RegionInfo {
 	origin := mc.MockRegionInfo(regionID, leaderStoreID, followerStoreIDs, learnerStoreIDs, nil)
diff --git a/server/schedule/checker/rule_checker.go b/server/schedule/checker/rule_checker.go
index 3765d09f8bf..f5f6276fda7 100644
--- a/server/schedule/checker/rule_checker.go
+++ b/server/schedule/checker/rule_checker.go
@@ -37,6 +37,7 @@ var (
 	errNoStoreToReplace   = errors.New("no store to replace peer")
 	errPeerCannotBeLeader = errors.New("peer cannot be leader")
 	errNoNewLeader        = errors.New("no new leader")
+	errRegionNoLeader     = errors.New("region no leader")
 )
 
 const maxPendingListLen = 100000
@@ -78,10 +79,17 @@ func (c *RuleChecker) Check(region *core.RegionInfo) *operator.Operator {
 
 // CheckWithFit is similar with Checker with placement.RegionFit
 func (c *RuleChecker) CheckWithFit(region *core.RegionInfo, fit *placement.RegionFit) (op *operator.Operator) {
+	// checker is paused
 	if c.IsPaused() {
 		checkerCounter.WithLabelValues("rule_checker", "paused").Inc()
 		return nil
 	}
+	// skip no leader region
+	if region.GetLeader() == nil {
+		checkerCounter.WithLabelValues("rule_checker", "region-no-leader").Inc()
+		log.Debug("fail to check region", zap.Uint64("region-id", region.GetID()), zap.Error(errRegionNoLeader))
+		return
+	}
 	// If the fit is fetched from cache, it seems that the region doesn't need cache
 	if c.cluster.GetOpts().IsPlacementRulesCacheEnabled() && fit.IsCached() {
 		failpoint.Inject("assertShouldNotCache", func() {
@@ -239,7 +247,7 @@ func (c *RuleChecker) fixLooseMatchPeer(region *core.RegionInfo, fit *placement.
 	if region.GetLeader().GetId() != peer.GetId() && rf.Rule.Role == placement.Leader {
 		checkerCounter.WithLabelValues("rule_checker", "fix-leader-role").Inc()
 		if c.allowLeader(fit, peer) {
-			return operator.CreateTransferLeaderOperator("fix-leader-role", c.cluster, region, region.GetLeader().StoreId, peer.GetStoreId(), []uint64{}, 0)
+			return operator.CreateTransferLeaderOperator("fix-leader-role", c.cluster, region, region.GetLeader().GetStoreId(), peer.GetStoreId(), []uint64{}, 0)
 		}
 		checkerCounter.WithLabelValues("rule_checker", "not-allow-leader")
 		return nil, errPeerCannotBeLeader
diff --git a/server/schedule/checker/rule_checker_test.go b/server/schedule/checker/rule_checker_test.go
index 4bbaffa9a49..a07a68575ab 100644
--- a/server/schedule/checker/rule_checker_test.go
+++ b/server/schedule/checker/rule_checker_test.go
@@ -263,6 +263,45 @@ func (suite *ruleCheckerTestSuite) TestFixRoleLeaderIssue3130() {
 	suite.Equal(uint64(1), op.Step(0).(operator.RemovePeer).FromStore)
 }
 
+func (suite *ruleCheckerTestSuite) TestFixLeaderRoleWithUnhealthyRegion() {
+	suite.cluster.AddLabelsStore(1, 1, map[string]string{"rule": "follower"})
+	suite.cluster.AddLabelsStore(2, 1, map[string]string{"rule": "follower"})
+	suite.cluster.AddLabelsStore(3, 1, map[string]string{"rule": "leader"})
+	suite.ruleManager.SetRuleGroup(&placement.RuleGroup{
+		ID:       "cluster",
+		Index:    2,
+		Override: true,
+	})
+	err := suite.ruleManager.SetRules([]*placement.Rule{
+		{
+			GroupID: "cluster",
+			ID:      "r1",
+			Index:   100,
+			Role:    placement.Follower,
+			Count:   2,
+			LabelConstraints: []placement.LabelConstraint{
+				{Key: "rule", Op: "in", Values: []string{"follower"}},
+			},
+		},
+		{
+			GroupID: "cluster",
+			ID:      "r2",
+			Index:   100,
+			Role:    placement.Leader,
+			Count:   1,
+			LabelConstraints: []placement.LabelConstraint{
+				{Key: "rule", Op: "in", Values: []string{"leader"}},
+			},
+		},
+	})
+	suite.NoError(err)
+	// no Leader
+	suite.cluster.AddNoLeaderRegion(1, 1, 2, 3)
+	r := suite.cluster.GetRegion(1)
+	op := suite.rc.Check(r)
+	suite.Nil(op)
+}
+
 func (suite *ruleCheckerTestSuite) TestBetterReplacement() {
 	suite.cluster.AddLabelsStore(1, 1, map[string]string{"host": "host1"})
 	suite.cluster.AddLabelsStore(2, 1, map[string]string{"host": "host1"})