diff --git a/spring-tx/src/main/java/org/springframework/transaction/annotation/ProxyTransactionManagementConfiguration.java b/spring-tx/src/main/java/org/springframework/transaction/annotation/ProxyTransactionManagementConfiguration.java
index 4469f5a0b7bf..c3352a30d463 100644
--- a/spring-tx/src/main/java/org/springframework/transaction/annotation/ProxyTransactionManagementConfiguration.java
+++ b/spring-tx/src/main/java/org/springframework/transaction/annotation/ProxyTransactionManagementConfiguration.java
@@ -19,6 +19,7 @@
 import org.springframework.beans.factory.config.BeanDefinition;
 import org.springframework.context.annotation.Bean;
 import org.springframework.context.annotation.Configuration;
+import org.springframework.context.annotation.ImportRuntimeHints;
 import org.springframework.context.annotation.Role;
 import org.springframework.transaction.config.TransactionManagementConfigUtils;
 import org.springframework.transaction.interceptor.BeanFactoryTransactionAttributeSourceAdvisor;
@@ -37,6 +38,7 @@
  */
 @Configuration(proxyBeanMethods = false)
 @Role(BeanDefinition.ROLE_INFRASTRUCTURE)
+@ImportRuntimeHints(TransactionRuntimeHintsRegistrar.class)
 public class ProxyTransactionManagementConfiguration extends AbstractTransactionManagementConfiguration {
 
 	@Bean(name = TransactionManagementConfigUtils.TRANSACTION_ADVISOR_BEAN_NAME)
diff --git a/spring-tx/src/main/java/org/springframework/transaction/annotation/TransactionRuntimeHintsRegistrar.java b/spring-tx/src/main/java/org/springframework/transaction/annotation/TransactionRuntimeHintsRegistrar.java
new file mode 100644
index 000000000000..bf32a734d7bf
--- /dev/null
+++ b/spring-tx/src/main/java/org/springframework/transaction/annotation/TransactionRuntimeHintsRegistrar.java
@@ -0,0 +1,47 @@
+/*
+ * Copyright 2002-2022 the original author or authors.
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+package org.springframework.transaction.annotation;
+
+import org.springframework.aot.hint.MemberCategory;
+import org.springframework.aot.hint.RuntimeHints;
+import org.springframework.aot.hint.RuntimeHintsRegistrar;
+import org.springframework.aot.hint.TypeReference;
+import org.springframework.aot.hint.support.RuntimeHintsUtils;
+
+import static java.util.Arrays.asList;
+
+/**
+ * {@link RuntimeHintsRegistrar} implementation that registers runtime hints for
+ * transaction management.
+ *
+ * @author Sebastien Deleuze
+ * @since 6.0
+ */
+public class TransactionRuntimeHintsRegistrar implements RuntimeHintsRegistrar {
+
+	@Override
+	public void registerHints(RuntimeHints hints, ClassLoader classLoader) {
+		RuntimeHintsUtils.registerAnnotation(hints, org.springframework.transaction.annotation.Transactional.class);
+
+		hints.reflection()
+				.registerTypes(asList(
+								TypeReference.of(org.springframework.transaction.annotation.Isolation.class),
+								TypeReference.of(org.springframework.transaction.annotation.Propagation.class),
+								TypeReference.of(org.springframework.transaction.TransactionDefinition.class)),
+						builder -> builder.withMembers(MemberCategory.DECLARED_FIELDS));
+	}
+}