diff --git a/node/script/build.ts b/node/script/build.ts
index 3453bda398a1c..95dacd076d3a3 100644
--- a/node/script/build.ts
+++ b/node/script/build.ts
@@ -41,7 +41,7 @@ const args = [
   'cmake-js',
   (REBUILD ? 'reconfigure' : 'configure'),
   `--arch=${ARCH}`,
-  '--CDnapi_build_version=3',
+  '--CDnapi_build_version=6',
   `--CDCMAKE_BUILD_TYPE=${CONFIG}`,
 ];
 if (ONNXRUNTIME_BUILD_DIR && typeof ONNXRUNTIME_BUILD_DIR === 'string') {
diff --git a/node/src/inference_session_wrap.cc b/node/src/inference_session_wrap.cc
index 78f32ec09250b..9f235d29d20b7 100644
--- a/node/src/inference_session_wrap.cc
+++ b/node/src/inference_session_wrap.cc
@@ -10,13 +10,16 @@
 #include "tensor_helper.h"
 
 Napi::FunctionReference InferenceSessionWrap::constructor;
-Ort::Env *InferenceSessionWrap::ortEnv;
 
 Napi::Object InferenceSessionWrap::Init(Napi::Env env, Napi::Object exports) {
   // create ONNX runtime env
   Ort::InitApi();
-  ortEnv = new Ort::Env{ORT_LOGGING_LEVEL_WARNING, "onnxruntime-node"};
-
+  ORT_NAPI_THROW_ERROR_IF(
+      Ort::Global<void>::api_ == nullptr, env,
+      "Failed to initialize ONNX Runtime API. It could happen when this nodejs binding was built with a higher version "
+      "ONNX Runtime but now runs with a lower version ONNX Runtime DLL(or shared library).");
+  auto ortEnv = new Ort::Env{ORT_LOGGING_LEVEL_WARNING, "onnxruntime-node"};
+  env.SetInstanceData(ortEnv);
   // initialize binding
   Napi::HandleScope scope(env);
 
@@ -28,7 +31,6 @@ Napi::Object InferenceSessionWrap::Init(Napi::Env env, Napi::Object exports) {
 
   constructor = Napi::Persistent(func);
   constructor.SuppressDestruct();
-
   exports.Set("InferenceSession", func);
   return exports;
 }
@@ -54,7 +56,7 @@ Napi::Value InferenceSessionWrap::LoadModel(const Napi::CallbackInfo &info) {
       Napi::String value = info[0].As<Napi::String>();
 
       ParseSessionOptions(info[1].As<Napi::Object>(), sessionOptions);
-      this->session_.reset(new Ort::Session(OrtEnv(),
+      this->session_.reset(new Ort::Session(*env.GetInstanceData<Ort::Env>(),
 #ifdef _WIN32
                                             reinterpret_cast<const wchar_t *>(value.Utf16Value().c_str()),
 #else
@@ -69,8 +71,9 @@ Napi::Value InferenceSessionWrap::LoadModel(const Napi::CallbackInfo &info) {
       int64_t bytesLength = info[2].As<Napi::Number>().Int64Value();
 
       ParseSessionOptions(info[1].As<Napi::Object>(), sessionOptions);
-      this->session_.reset(
-          new Ort::Session(OrtEnv(), reinterpret_cast<char *>(buffer) + bytesOffset, bytesLength, sessionOptions));
+      this->session_.reset(new Ort::Session(*env.GetInstanceData<Ort::Env>(),
+                                            reinterpret_cast<char *>(buffer) + bytesOffset, bytesLength,
+                                            sessionOptions));
     } else {
       ORT_NAPI_THROW_TYPEERROR(
           env,
diff --git a/node/src/inference_session_wrap.h b/node/src/inference_session_wrap.h
index 8298819288947..1a51a70a836cf 100644
--- a/node/src/inference_session_wrap.h
+++ b/node/src/inference_session_wrap.h
@@ -54,10 +54,6 @@ class InferenceSessionWrap : public Napi::ObjectWrap<InferenceSessionWrap> {
   // persistent constructor
   static Napi::FunctionReference constructor;
 
-  // global env
-  static Ort::Env *ortEnv;
-  static Ort::Env &OrtEnv() { return *ortEnv; }
-
   // session objects
   bool initialized_;
   std::unique_ptr<Ort::Session> session_;