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KP.2.3(no 31del)+S:T572I(96 seqs, 5 countries) #1735

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xz-keg opened this issue Jul 13, 2024 · 6 comments
Closed

KP.2.3(no 31del)+S:T572I(96 seqs, 5 countries) #1735

xz-keg opened this issue Jul 13, 2024 · 6 comments

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@xz-keg
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xz-keg commented Jul 13, 2024

Most KP.2.3 has S:31del, however the 31del is after the KP.2.3 defining mutations of S:H146Q, Orf3a:K67N
I find a KP.2.3 sub-branch with S:T572I that emerges from a KP.2.3 branch before the S:31del.

KP.2.3(no 31del)+C23277T(S:T572I)+C7420T

GISAID query for C7420T branch only : C7420T,C22000A, C23277T, G25593T
GISAID query for general no-31del S:T572I branch: C22000A, C23277T, G25593T, -del21653, -28714
No. of seqs: 32(Israel 5 USA 27(2 from France))

First: EPI_ISL_19233571, 2024-4-16, USA
Latest: EPI_ISL_19256471, 2024-7-3, Israel

Usher cannot handle deletions so put this branch together with other KP.2.3+S:T572I branches with S:S31del.

usher
image

@FedeGueli
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I was thinking it could have been recombination with a KP.3.3.1 Canadian branch but being there G15543T it would mean multiple breakpoints so it is likely just homoplasy

@xz-keg
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xz-keg commented Jul 18, 2024

38, Canada

@xz-keg xz-keg changed the title KP.2.3(no 31del)+S:T572I(32 seqs, 3 countries) KP.2.3(no 31del)+S:T572I(38 seqs, 4 countries) Jul 18, 2024
@xz-keg xz-keg changed the title KP.2.3(no 31del)+S:T572I(38 seqs, 4 countries) KP.2.3(no 31del)+S:T572I(44 seqs, 4 countries) Jul 23, 2024
@xz-keg xz-keg changed the title KP.2.3(no 31del)+S:T572I(44 seqs, 4 countries) KP.2.3(no 31del)+S:T572I(60 seqs, 4 countries) Jul 29, 2024
@xz-keg xz-keg changed the title KP.2.3(no 31del)+S:T572I(60 seqs, 4 countries) KP.2.3(no 31del)+S:T572I(67 seqs, 4 countries) Aug 3, 2024
@xz-keg
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xz-keg commented Aug 8, 2024

80, Spain

@xz-keg xz-keg changed the title KP.2.3(no 31del)+S:T572I(67 seqs, 4 countries) KP.2.3(no 31del)+S:T572I(80 seqs, 5 countries) Aug 8, 2024
@FedeGueli FedeGueli added the To be proposed Green light for proposal label Aug 8, 2024
@FedeGueli
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pls propose it

@FedeGueli FedeGueli changed the title KP.2.3(no 31del)+S:T572I(80 seqs, 5 countries) KP.2.3(no 31del)+S:T572I(96 seqs, 5 countries) Aug 8, 2024
@FedeGueli
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96 now with a big batch from. texas uploaded after your last update

FedeGueli referenced this issue in cov-lineages/pango-designation Oct 22, 2024
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