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JN.1.42.2 plus S:S31del and Orf1a:E940G (62 , Central America - <10% of samples related to El Salvador and collected after July 1) #1692

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FedeGueli opened this issue Jul 4, 2024 · 2 comments
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designated Emerged in an undersampled area Actual infection toll may be much larger than number of sequences suggest S:31 S:346
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@FedeGueli
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I spotted back weeks ago in #1502 a sublineage of JN.1.42.2 (346T) with S:S31del, it turned out to have grown a lot and more interestingly it has been sampled multiple times by GBW in American airports. This could point to some sort of prevalence in some undersampled area or more unlikely towarrd a rapid growth.

Defining mutations:
JN.1.42.2 > Orf1a:E940G (A3084G),S:S31del (del21653-55 )
Query:A3084G,del21653
Samples:35
Countries: GBW (8 El Salvador, 2 Mexico, 1 Nicaragua, Uk, HK-CHN ),California, Spain

Genomes EPI_ISL_19168259, EPI_ISL_19175848, EPI_ISL_19188499, EPI_ISL_19191567, EPI_ISL_19195014, EPI_ISL_19195593, EPI_ISL_19195602, EPI_ISL_19195715, EPI_ISL_19195722, EPI_ISL_19195777, EPI_ISL_19195906, EPI_ISL_19195930, EPI_ISL_19197516, EPI_ISL_19199370, EPI_ISL_19199486, EPI_ISL_19199496, EPI_ISL_19203034, EPI_ISL_19203037, EPI_ISL_19205991, EPI_ISL_19210165, EPI_ISL_19210174, EPI_ISL_19210253, EPI_ISL_19210334, EPI_ISL_19215294, EPI_ISL_19215331, EPI_ISL_19215344, EPI_ISL_19221242, EPI_ISL_19222839, EPI_ISL_19223237, EPI_ISL_19229608, EPI_ISL_19229634, EPI_ISL_19229675, EPI_ISL_19229787, EPI_ISL_19229800, EPI_ISL_19229818
[Tree: ]( https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_52347_6b6720.json?c=userOrOld&label=id:node_7149164) Screenshot 2024-07-04 alle 16 55 09 Screenshot 2024-07-04 alle 16 56 09
@FedeGueli FedeGueli changed the title JN.1.42.2 plus S:S31del and Orf1a:E940G (35 , Central America) JN.1.42.2 plus S:S31del and Orf1a:E940G (35 , Central America - 40% of samples related to El Salvador after June 1) Jul 4, 2024
@FedeGueli FedeGueli added the Emerged in an undersampled area Actual infection toll may be much larger than number of sequences suggest label Jul 8, 2024
@FedeGueli FedeGueli changed the title JN.1.42.2 plus S:S31del and Orf1a:E940G (35 , Central America - 40% of samples related to El Salvador after June 1) JN.1.42.2 plus S:S31del and Orf1a:E940G (39 , Central America - 40% of samples related to El Salvador after June 1) Jul 11, 2024
@FedeGueli FedeGueli changed the title JN.1.42.2 plus S:S31del and Orf1a:E940G (39 , Central America - 40% of samples related to El Salvador after June 1) JN.1.42.2 plus S:S31del and Orf1a:E940G (51 , Central America - 10% of samples related to El Salvador and collected after June 16) Aug 3, 2024
@FedeGueli FedeGueli changed the title JN.1.42.2 plus S:S31del and Orf1a:E940G (51 , Central America - 10% of samples related to El Salvador and collected after June 16) JN.1.42.2 plus S:S31del and Orf1a:E940G (57 , Central America - <10% of samples related to El Salvador and collected after July 1) Aug 7, 2024
@FedeGueli
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57 now but its prevalence in the area where emerged is decreasing.

@FedeGueli FedeGueli changed the title JN.1.42.2 plus S:S31del and Orf1a:E940G (57 , Central America - <10% of samples related to El Salvador and collected after July 1) JN.1.42.2 plus S:S31del and Orf1a:E940G (62 , Central America - <10% of samples related to El Salvador and collected after July 1) Aug 10, 2024
@xz-keg
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xz-keg commented Aug 15, 2024

Designated MS.1 via cov-lineages/pango-designation@beb1f1f

@xz-keg xz-keg closed this as completed Aug 15, 2024
@xz-keg xz-keg added this to the MS.1 milestone Aug 15, 2024
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