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Multiple BA.2.86*+S:T95X 9 ongoing branchs as 2/28 #1135

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9 of 14 tasks
xz-keg opened this issue Dec 1, 2023 · 15 comments
Closed
9 of 14 tasks

Multiple BA.2.86*+S:T95X 9 ongoing branchs as 2/28 #1135

xz-keg opened this issue Dec 1, 2023 · 15 comments
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Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. BA.2.86 designated Multiple lineages partially designated S:95
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@xz-keg
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xz-keg commented Dec 1, 2023

Besides JQ.1, there seems to be multiple BA.2.86* with S:T95I

Query for all seqs: A7842, C8293T, G8393A, Spike_T95 (554 seqs)

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Doublets:

  1. BA.2.86.1+Orf1a:S2193F,L3829F, Orf1b:T1743I,S:T95I: Query: C21846T,A6183G,C12815T,C11750T, UK dead
  2. JN.1+Orf1a:T2183I+Orf1b:P1287S,S:T95I,S691P. Query: C21846T,C17326T,T23633C, UK (1 not on GISAID) dead
  3. JN.1.4+Orf1b:M187A+Orf1a:I2490T,A1679V,A4257V, S:T95I,Orf8:I9T. Query: C774T, C21846T, A14026G, Sweden dead
  4. JN.1.1+T27785C+S:S12F,S:T95I Query: C9142T,T27785C, C21846T, Switzerland Dead
  5. Multiple JN.1 + S:R346X + FliRT + Trio : 155 branches as July 30 #1089 branch 3+S:T95I : Query: C22599C,C11747T,C21846T, C1762A, France
  6. JN.1+Orf1b:G1568S,S:T95I: Query: G18169A,C21846T,T3565C, UK Dead

Singlets:

  1. JN.1.1+Orf1a:T2800N+Orf1a:H2092Y+S:T95I. Query: C11747T, C21846T, C1063T, Canada dead
  2. JN.1.19(Orf8:I71V)+N:P46S, S:T95I, Query: C1060T,C21846T,A6183G,T3565C, Denmark dead
  3. JN.2.2+S:T95I, Query: T1030C,C21846T,A2127G, Germany dead
  4. JN.2+G28378T+S:T95I, Query: C21846T,G28378T,A2127G,A6183G, China Dead
  5. JN.1+C26894T+C25680T+S:T95I, Query: C26894T,T3565C,C21846T, USA, 2 seqs
  6. JN.1.4+S:T95N, Query:C774T,C21846A, USA
  7. JN.3 plus S:T572I (8 UK) #1091+S:T95S, Query: C23277T,C21846G, UK dead
  8. BA.2.86+S:T95S,Orf3a:A110S, Query: C21846G, G25720T,C11008T, South Africa dead

usher for Branch 1 :
usher
image

usher for Branch 2:
usher
image

@FedeGueli
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FedeGueli commented Dec 19, 2023

Branch 3 at 7 updated the others

@FedeGueli FedeGueli changed the title Multiple BA.2.86*+S:T95I Multiple BA.2.86*+S:T95I as 12/19 Dec 19, 2023
@FedeGueli FedeGueli changed the title Multiple BA.2.86*+S:T95I as 12/19 Multiple BA.2.86*+S:T95I 7 as 12/24 Dec 24, 2023
@FedeGueli
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B1 > 18
B2 > 11

B3 and B4 appear to be slow.

@xz-keg
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xz-keg commented Jan 2, 2024

A previous doublet is now 4 seqs and becomes B5

@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I 7 as 12/24 Multiple BA.2.86*+S:T95I 5 as 1/11 Jan 11, 2024
@xz-keg
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xz-keg commented Jan 11, 2024

1/11:
Add singlet 4,5 Doublet 2.
Branch 1 becomes 23 and Branch 2 becomes 21.

@FedeGueli
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Please propose branch 1 and branch 2.

@FedeGueli
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Branch 2 Designated JN.1.10 via cov-lineages/pango-designation@65d1e22

@FedeGueli FedeGueli added designated partially designated and removed To be proposed Green light for proposal labels Jan 11, 2024
@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I 5 as 1/11 Multiple BA.2.86*+S:T95I or T95N or T95L 4 as 1/15 Jan 15, 2024
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xz-keg commented Jan 15, 2024

@AngieHinrichs, it seems that JQ.1 with 487 missing coverage are all categorized into BA.2.86.3+G487A+S:T95I sub-branch despite no seq actually have G487A, better fix it.

usher

@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95L 4 as 1/15 Multiple BA.2.86*+S:T95I or T95N or T95S 5 as 1/15 Jan 15, 2024
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xz-keg commented Jan 15, 2024

1-15, Add some S:T95S and S:T95N branches (most of them already died off though)

@AngieHinrichs
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AngieHinrichs commented Jan 18, 2024

@AngieHinrichs, it seems that JQ.1 with 487 missing coverage are all categorized into BA.2.86.3+G487A+S:T95I sub-branch despite no seq actually have G487A, better fix it.

Thanks -- I think that is fixed as of the 2024-01-17 tree.

@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95S 5 as 1/15 Multiple BA.2.86*+S:T95I or T95N or T95S 5 as 1/20 Jan 20, 2024
@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95S 5 as 1/20 Multiple BA.2.86*+S:T95I or T95N or T95S 7 as 2/4 Feb 4, 2024
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xz-keg commented Feb 4, 2024

2/4: Add branch 7 and branch 8.

@FedeGueli
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It seems just branch 3 has some chances to emerge. lets keep this open for a while more.

@FedeGueli FedeGueli added the Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. label Feb 10, 2024
@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95S 7 as 2/4 Multiple BA.2.86*+S:T95I or T95N or T95S 9 ongoing branchs as 2/15 Feb 15, 2024
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xz-keg commented Feb 15, 2024

2/15: Add branch 9 and 10

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xz-keg commented Feb 28, 2024

2/28, Add branch 11-13

@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95S 9 ongoing branchs as 2/15 Multiple BA.2.86*+S:T95I or T95N or T95S 9 ongoing branchs as 2/28 Feb 28, 2024
@xz-keg xz-keg changed the title Multiple BA.2.86*+S:T95I or T95N or T95S 9 ongoing branchs as 2/28 Multiple BA.2.86*+S:T95X 9 ongoing branchs as 2/28 Feb 28, 2024
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xz-keg commented Mar 9, 2024

Seems that all branches are not growing.

@xz-keg xz-keg closed this as completed Mar 9, 2024
@FedeGueli
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Thanks ! agree with u

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Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. BA.2.86 designated Multiple lineages partially designated S:95
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