diff --git a/docs/guide/api-plugin.md b/docs/guide/api-plugin.md
index 50353765261e34..76b9984a069828 100644
--- a/docs/guide/api-plugin.md
+++ b/docs/guide/api-plugin.md
@@ -305,6 +305,28 @@ Vite plugins can also provide hooks that serve Vite-specific purposes. These hoo
 
   Note `configureServer` is not called when running the production build so your other hooks need to guard against its absence.
 
+### `configurePreviewServer`
+
+- **Type:** `(server: { middlewares: Connect.Server, httpServer: http.Server }) => (() => void) | void | Promise<(() => void) | void>`
+- **Kind:** `async`, `sequential`
+
+  Same as [`configureServer`](/guide/api-plugin.html#configureserver) but for the preview server. It provides the [connect](https://github.com/senchalabs/connect) server and its underlying [http server](https://nodejs.org/api/http.html). Similarly to `configureServer`, the `configurePreviewServer` hook is called before other middlewares are installed. If you want to inject a middleware **after** other middlewares, you can return a function from `configurePreviewServer`, which will be called after internal middlewares are installed:
+
+  ```js
+  const myPlugin = () => ({
+    name: 'configure-preview-server',
+    configurePreviewServer(server) {
+      // return a post hook that is called after other middlewares are
+      // installed
+      return () => {
+        server.middlewares.use((req, res, next) => {
+          // custom handle request...
+        })
+      }
+    }
+  })
+  ```
+
 ### `transformIndexHtml`
 
 - **Type:** `IndexHtmlTransformHook | { enforce?: 'pre' | 'post', transform: IndexHtmlTransformHook }`
diff --git a/packages/vite/src/node/index.ts b/packages/vite/src/node/index.ts
index 2e849d846527ca..901c5b943f8e14 100644
--- a/packages/vite/src/node/index.ts
+++ b/packages/vite/src/node/index.ts
@@ -33,6 +33,7 @@ export type {
 export type {
   PreviewOptions,
   PreviewServer,
+  PreviewServerHook,
   ResolvedPreviewOptions
 } from './preview'
 export type {
diff --git a/packages/vite/src/node/plugin.ts b/packages/vite/src/node/plugin.ts
index c613fe5f180d07..adf647d6d5500f 100644
--- a/packages/vite/src/node/plugin.ts
+++ b/packages/vite/src/node/plugin.ts
@@ -12,6 +12,7 @@ import type { ServerHook } from './server'
 import type { IndexHtmlTransform } from './plugins/html'
 import type { ModuleNode } from './server/moduleGraph'
 import type { HmrContext } from './server/hmr'
+import type { PreviewServerHook } from './preview'
 import type { ConfigEnv, ResolvedConfig } from './'
 
 /**
@@ -79,6 +80,15 @@ export interface Plugin extends RollupPlugin {
    * are applied. Hook can be async functions and will be called in series.
    */
   configureServer?: ServerHook
+  /**
+   * Configure the preview server. The hook receives the connect server and
+   * its underlying http server.
+   *
+   * The hooks are called before other middlewares are applied. A hook can
+   * return a post hook that will be called after other middlewares are
+   * applied. Hooks can be async functions and will be called in series.
+   */
+  configurePreviewServer?: PreviewServerHook
   /**
    * Transform index.html.
    * The hook receives the following arguments:
diff --git a/packages/vite/src/node/preview.ts b/packages/vite/src/node/preview.ts
index a230ab5b57421d..8debe521353b84 100644
--- a/packages/vite/src/node/preview.ts
+++ b/packages/vite/src/node/preview.ts
@@ -1,5 +1,6 @@
 import path from 'path'
 import type { Server } from 'http'
+import type * as http from 'http'
 import connect from 'connect'
 import sirv from 'sirv'
 import type { Connect } from 'types/connect'
@@ -53,6 +54,11 @@ export interface PreviewServer {
   printUrls: () => void
 }
 
+export type PreviewServerHook = (server: {
+  middlewares: Connect.Server
+  httpServer: http.Server
+}) => (() => void) | void | Promise<(() => void) | void>
+
 /**
  * Starts the Vite server in preview mode, to simulate a production deployment
  * @experimental
@@ -69,6 +75,16 @@ export async function preview(
     await resolveHttpsConfig(config.preview?.https, config.cacheDir)
   )
 
+  // apply server hooks from plugins
+  const postHooks: ((() => void) | void)[] = []
+  for (const plugin of config.plugins) {
+    if (plugin.configurePreviewServer) {
+      postHooks.push(
+        await plugin.configurePreviewServer({ middlewares: app, httpServer })
+      )
+    }
+  }
+
   // cors
   const { cors } = config.preview
   if (cors !== false) {
@@ -83,6 +99,7 @@ export async function preview(
 
   app.use(compression())
 
+  // static assets
   const distDir = path.resolve(config.root, config.build.outDir)
   app.use(
     config.base,
@@ -93,6 +110,9 @@ export async function preview(
     })
   )
 
+  // apply post server hooks from plugins
+  postHooks.forEach((fn) => fn && fn())
+
   const options = config.preview
   const hostname = resolveHostname(options.host)
   const port = options.port ?? 4173