diff --git a/.changeset/shiny-timers-bake.md b/.changeset/shiny-timers-bake.md
new file mode 100644
index 00000000000..9c815ee3251
--- /dev/null
+++ b/.changeset/shiny-timers-bake.md
@@ -0,0 +1,5 @@
+---
+"@remix-run/dev": patch
+---
+
+Add `@remix-run/node` to Vite's `optimizeDeps.include` array
diff --git a/packages/remix-dev/vite/plugin.ts b/packages/remix-dev/vite/plugin.ts
index b8ffd45b909..c0c3f5e4144 100644
--- a/packages/remix-dev/vite/plugin.ts
+++ b/packages/remix-dev/vite/plugin.ts
@@ -557,6 +557,7 @@ export const remixVitePlugin: RemixVitePlugin = (options = {}) => {
               // That means that before Vite pre-bundles dependencies (e.g. first time dev server is run)
               // mismatching Remix routers cause `Error: You must render this element inside a <Remix> element`.
               "@remix-run/react",
+              "@remix-run/node",
             ],
           },
           esbuild: {