diff --git a/.chloggen/awsxrayexporter_jdbc_fix.yaml b/.chloggen/awsxrayexporter_jdbc_fix.yaml
new file mode 100644
index 000000000000..c160f14badf1
--- /dev/null
+++ b/.chloggen/awsxrayexporter_jdbc_fix.yaml
@@ -0,0 +1,27 @@
+# Use this changelog template to create an entry for release notes.
+
+# One of 'breaking', 'deprecation', 'new_component', 'enhancement', 'bug_fix'
+change_type: bug_fix
+
+# The name of the component, or a single word describing the area of concern, (e.g. filelogreceiver)
+component: awsxrayexporter
+
+# A brief description of the change.  Surround your text with quotes ("") if it needs to start with a backtick (`).
+note: Fix the DB subsegment(client span) name with JDBC conn string starts with "jdbc:"
+
+# Mandatory: One or more tracking issues related to the change. You can use the PR number here if no issue exists.
+issues: [33225]
+
+# (Optional) One or more lines of additional information to render under the primary note.
+# These lines will be padded with 2 spaces and then inserted directly into the document.
+# Use pipe (|) for multiline entries.
+subtext:
+
+# If your change doesn't affect end users or the exported elements of any package,
+# you should instead start your pull request title with [chore] or use the "Skip Changelog" label.
+# Optional: The change log or logs in which this entry should be included.
+# e.g. '[user]' or '[user, api]'
+# Include 'user' if the change is relevant to end users.
+# Include 'api' if there is a change to a library API.
+# Default: '[user]'
+change_logs: []
diff --git a/exporter/awsxrayexporter/internal/translator/segment.go b/exporter/awsxrayexporter/internal/translator/segment.go
index 5fe72117aeeb..9460f1ce5c67 100644
--- a/exporter/awsxrayexporter/internal/translator/segment.go
+++ b/exporter/awsxrayexporter/internal/translator/segment.go
@@ -418,7 +418,10 @@ func MakeSegment(span ptrace.Span, resource pcommon.Resource, indexedAttrs []str
 			// For database queries, the segment name convention is <db name>@<db host>
 			name = dbInstance.Str()
 			if dbURL, ok := attributes.Get(conventions.AttributeDBConnectionString); ok {
-				if parsed, _ := url.Parse(dbURL.Str()); parsed != nil {
+				// Trim JDBC connection string if starts with "jdbc:", otherwise no change
+				// jdbc:mysql://db.dev.example.com:3306
+				dbURLStr := strings.TrimPrefix(dbURL.Str(), "jdbc:")
+				if parsed, _ := url.Parse(dbURLStr); parsed != nil {
 					if parsed.Hostname() != "" {
 						name += "@" + parsed.Hostname()
 					}
diff --git a/exporter/awsxrayexporter/internal/translator/segment_test.go b/exporter/awsxrayexporter/internal/translator/segment_test.go
index 7acd7428084d..8426e2e976ac 100644
--- a/exporter/awsxrayexporter/internal/translator/segment_test.go
+++ b/exporter/awsxrayexporter/internal/translator/segment_test.go
@@ -226,7 +226,7 @@ func TestClientSpanWithDbComponent(t *testing.T) {
 	attributes[conventions.AttributeDBName] = "customers"
 	attributes[conventions.AttributeDBStatement] = spanName
 	attributes[conventions.AttributeDBUser] = "userprefsvc"
-	attributes[conventions.AttributeDBConnectionString] = "mysql://db.dev.example.com:3306"
+	attributes[conventions.AttributeDBConnectionString] = "jdbc:mysql://db.dev.example.com:3306"
 	attributes[conventions.AttributeNetPeerName] = "db.dev.example.com"
 	attributes[conventions.AttributeNetPeerPort] = "3306"
 	attributes["enterprise.app.id"] = enterpriseAppID