diff --git a/extensions/resteasy-reactive/jaxrs-client-reactive/deployment/src/main/java/io/quarkus/jaxrs/client/reactive/deployment/JaxrsClientReactiveProcessor.java b/extensions/resteasy-reactive/jaxrs-client-reactive/deployment/src/main/java/io/quarkus/jaxrs/client/reactive/deployment/JaxrsClientReactiveProcessor.java
index 86edc4adff49d..8f79b818fad4a 100644
--- a/extensions/resteasy-reactive/jaxrs-client-reactive/deployment/src/main/java/io/quarkus/jaxrs/client/reactive/deployment/JaxrsClientReactiveProcessor.java
+++ b/extensions/resteasy-reactive/jaxrs-client-reactive/deployment/src/main/java/io/quarkus/jaxrs/client/reactive/deployment/JaxrsClientReactiveProcessor.java
@@ -314,6 +314,28 @@ public void accept(EndpointIndexer.ResourceMethodCallbackData entry) {
                                         QuarkusResteasyReactiveDotNames.IGNORE_METHOD_FOR_REFLECTION_PREDICATE)
                                 .source(source)
                                 .build());
+
+                        // if there is a body parameter type, register it for reflection
+                        ResourceMethod resourceMethod = entry.getResourceMethod();
+                        MethodParameter[] methodParameters = resourceMethod.getParameters();
+                        if (methodParameters != null) {
+                            for (int i = 0; i < methodParameters.length; i++) {
+                                MethodParameter methodParameter = methodParameters[i];
+                                if (methodParameter.getParameterType() == ParameterType.BODY) {
+                                    reflectiveHierarchyBuildItemBuildProducer.produce(new ReflectiveHierarchyBuildItem.Builder()
+                                            .type(method.parameterType(i))
+                                            .index(index)
+                                            .ignoreTypePredicate(
+                                                    QuarkusResteasyReactiveDotNames.IGNORE_TYPE_FOR_REFLECTION_PREDICATE)
+                                            .ignoreFieldPredicate(
+                                                    QuarkusResteasyReactiveDotNames.IGNORE_FIELD_FOR_REFLECTION_PREDICATE)
+                                            .ignoreMethodPredicate(
+                                                    QuarkusResteasyReactiveDotNames.IGNORE_METHOD_FOR_REFLECTION_PREDICATE)
+                                            .source(source)
+                                            .build());
+                                }
+                            }
+                        }
                     }
                 })
                 .build();
diff --git a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
index 9e88e5bd86c63..9e94a122f1f6b 100644
--- a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
+++ b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
@@ -118,6 +118,9 @@ void init(@Observes Router router) {
         router.post("/hello").handler(rc -> rc.response().putHeader("content-type", MediaType.TEXT_PLAIN)
                 .end("Hello, " + (rc.getBodyAsString()).repeat(getCount(rc))));
 
+        router.post("/hello/fromMessage").handler(rc -> rc.response().putHeader("content-type", MediaType.TEXT_PLAIN)
+                .end(rc.body().asJsonObject().getString("message")));
+
         router.route("/call-hello-client").blockingHandler(rc -> {
             String url = rc.getBody().toString();
             HelloClient client = RestClientBuilder.newBuilder().baseUri(URI.create(url))
@@ -126,6 +129,14 @@ void init(@Observes Router router) {
             rc.response().end(greeting);
         });
 
+        router.route("/call-helloFromMessage-client").blockingHandler(rc -> {
+            String url = rc.getBody().toString();
+            HelloClient client = RestClientBuilder.newBuilder().baseUri(URI.create(url))
+                    .build(HelloClient.class);
+            String greeting = client.fromMessage(new HelloClient.Message("Hello world"));
+            rc.response().end(greeting);
+        });
+
         router.post("/params/param").handler(rc -> rc.response().putHeader("content-type", MediaType.TEXT_PLAIN)
                 .end(getParam(rc)));
 
diff --git a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/HelloClient.java b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/HelloClient.java
index bc09e13d357ac..4d9ade9614667 100644
--- a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/HelloClient.java
+++ b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/HelloClient.java
@@ -9,6 +9,8 @@
 import javax.ws.rs.core.MediaType;
 import javax.ws.rs.core.Response;
 
+import com.fasterxml.jackson.annotation.JsonCreator;
+
 import io.quarkus.rest.client.reactive.ClientExceptionMapper;
 
 @Path("")
@@ -18,6 +20,12 @@ public interface HelloClient {
     @Consumes(MediaType.TEXT_PLAIN)
     String greeting(String name, @QueryParam("count") int count);
 
+    @Path("fromMessage")
+    @POST
+    @Produces(MediaType.TEXT_PLAIN)
+    @Consumes(MediaType.APPLICATION_JSON)
+    String fromMessage(Message message);
+
     // this isn't used, but it makes sure that the generated provider can be properly instantiated in native mode
     @ClientExceptionMapper
     static RuntimeException toException(Response response) {
@@ -26,4 +34,18 @@ static RuntimeException toException(Response response) {
         }
         return null;
     }
+
+    class Message {
+
+        private final String message;
+
+        @JsonCreator
+        public Message(String message) {
+            this.message = message;
+        }
+
+        public String getMessage() {
+            return message;
+        }
+    }
 }
diff --git a/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/BasicTest.java b/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/BasicTest.java
index 937d70633a9fb..bfe4f408ed506 100644
--- a/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/BasicTest.java
+++ b/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/BasicTest.java
@@ -42,6 +42,12 @@ public void shouldMakeTextRequest() {
         assertThat(response.asString()).isEqualTo("Hello, JohnJohn");
     }
 
+    @Test
+    public void shouldMakeJsonRequestAndGetTextResponse() {
+        Response response = RestAssured.with().body(helloUrl).post("/call-helloFromMessage-client");
+        assertThat(response.asString()).isEqualTo("Hello world");
+    }
+
     @Test
     public void restResponseShouldWorkWithNonSuccessfulResponse() {
         Response response = RestAssured.with().body(helloUrl).post("/rest-response");