diff --git a/extensions/opentelemetry/opentelemetry/runtime/src/main/java/io/quarkus/opentelemetry/runtime/tracing/vertx/HttpInstrumenterVertxTracer.java b/extensions/opentelemetry/opentelemetry/runtime/src/main/java/io/quarkus/opentelemetry/runtime/tracing/vertx/HttpInstrumenterVertxTracer.java
index 162af7b40b289..0e21f0d2bdbc3 100644
--- a/extensions/opentelemetry/opentelemetry/runtime/src/main/java/io/quarkus/opentelemetry/runtime/tracing/vertx/HttpInstrumenterVertxTracer.java
+++ b/extensions/opentelemetry/opentelemetry/runtime/src/main/java/io/quarkus/opentelemetry/runtime/tracing/vertx/HttpInstrumenterVertxTracer.java
@@ -1,6 +1,5 @@
 package io.quarkus.opentelemetry.runtime.tracing.vertx;
 
-import static io.netty.handler.codec.http.HttpResponseStatus.NOT_FOUND;
 import static io.opentelemetry.instrumentation.api.instrumenter.http.HttpRouteSource.FILTER;
 import static io.opentelemetry.semconv.trace.attributes.SemanticAttributes.HTTP_CLIENT_IP;
 import static io.quarkus.opentelemetry.runtime.OpenTelemetryConfig.INSTRUMENTATION_NAME;
@@ -17,6 +16,7 @@
 import io.opentelemetry.instrumentation.api.instrumenter.AttributesExtractor;
 import io.opentelemetry.instrumentation.api.instrumenter.Instrumenter;
 import io.opentelemetry.instrumentation.api.instrumenter.InstrumenterBuilder;
+import io.opentelemetry.instrumentation.api.instrumenter.SpanNameExtractor;
 import io.opentelemetry.instrumentation.api.instrumenter.http.HttpClientAttributesExtractor;
 import io.opentelemetry.instrumentation.api.instrumenter.http.HttpClientAttributesGetter;
 import io.opentelemetry.instrumentation.api.instrumenter.http.HttpRouteBiGetter;
@@ -31,6 +31,7 @@
 import io.vertx.core.http.HttpMethod;
 import io.vertx.core.http.HttpServerRequest;
 import io.vertx.core.http.HttpVersion;
+import io.vertx.core.http.impl.HttpRequestHead;
 import io.vertx.core.http.impl.headers.HeadersAdaptor;
 import io.vertx.core.http.impl.headers.HeadersMultiMap;
 import io.vertx.core.net.SocketAddress;
@@ -125,7 +126,7 @@ private static Instrumenter<HttpRequest, HttpResponse> getClientInstrumenter(fin
         InstrumenterBuilder<HttpRequest, HttpResponse> clientBuilder = Instrumenter.builder(
                 openTelemetry,
                 INSTRUMENTATION_NAME,
-                HttpSpanNameExtractor.create(clientAttributesExtractor));
+                new ClientSpanNameExtractor(clientAttributesExtractor));
 
         return clientBuilder
                 .setSpanStatusExtractor(HttpSpanStatusExtractor.create(serverAttributesExtractor))
@@ -357,6 +358,33 @@ public List<String> responseHeader(final HttpRequest request, final HttpResponse
         }
     }
 
+    private static class ClientSpanNameExtractor implements SpanNameExtractor<HttpRequest> {
+
+        private final SpanNameExtractor<HttpRequest> http;
+
+        ClientSpanNameExtractor(ClientAttributesExtractor clientAttributesExtractor) {
+            this.http = HttpSpanNameExtractor.create(clientAttributesExtractor);
+        }
+
+        @Override
+        public String extract(HttpRequest httpRequest) {
+            if (httpRequest instanceof HttpRequestHead) {
+                HttpRequestHead head = (HttpRequestHead) httpRequest;
+                if (head.traceOperation != null) {
+                    return head.traceOperation;
+                }
+            }
+            if (httpRequest instanceof WriteHeadersHttpRequest) {
+                WriteHeadersHttpRequest writeHeaders = (WriteHeadersHttpRequest) httpRequest;
+                String traceOperation = writeHeaders.traceOperation();
+                if (traceOperation != null) {
+                    return traceOperation;
+                }
+            }
+            return http.extract(httpRequest);
+        }
+    }
+
     private static class HttpRequestTextMapSetter implements TextMapSetter<HttpRequest> {
         @Override
         public void set(final HttpRequest carrier, final String key, final String value) {
@@ -481,6 +509,13 @@ public SocketAddress remoteAddress() {
             return httpRequest.remoteAddress();
         }
 
+        public String traceOperation() {
+            if (httpRequest instanceof HttpRequestHead) {
+                return ((HttpRequestHead) httpRequest).traceOperation;
+            }
+            return null;
+        }
+
         static WriteHeadersHttpRequest request(HttpRequest httpRequest, BiConsumer<String, String> headers) {
             return new WriteHeadersHttpRequest(httpRequest, headers);
         }
diff --git a/integration-tests/opentelemetry/pom.xml b/integration-tests/opentelemetry/pom.xml
index 3642042ff1b89..59d954f3dfd52 100644
--- a/integration-tests/opentelemetry/pom.xml
+++ b/integration-tests/opentelemetry/pom.xml
@@ -35,6 +35,12 @@
             <artifactId>quarkus-rest-client</artifactId>
         </dependency>
 
+        <!-- Vertx WebClient -->
+        <dependency>
+            <groupId>io.smallrye.reactive</groupId>
+            <artifactId>smallrye-mutiny-vertx-web-client</artifactId>
+        </dependency>
+
         <!-- Needed for InMemorySpanExporter to verify captured traces -->
         <dependency>
             <groupId>io.opentelemetry</groupId>
diff --git a/integration-tests/opentelemetry/src/main/java/io/quarkus/it/opentelemetry/PingPongResource.java b/integration-tests/opentelemetry/src/main/java/io/quarkus/it/opentelemetry/PingPongResource.java
index b875008a6b972..af49b27dae0da 100644
--- a/integration-tests/opentelemetry/src/main/java/io/quarkus/it/opentelemetry/PingPongResource.java
+++ b/integration-tests/opentelemetry/src/main/java/io/quarkus/it/opentelemetry/PingPongResource.java
@@ -6,11 +6,20 @@
 import javax.ws.rs.Path;
 import javax.ws.rs.PathParam;
 
+import org.eclipse.microprofile.config.inject.ConfigProperty;
 import org.eclipse.microprofile.rest.client.inject.RegisterRestClient;
 import org.eclipse.microprofile.rest.client.inject.RestClient;
 
 import io.smallrye.common.annotation.Blocking;
 import io.smallrye.mutiny.Uni;
+import io.vertx.core.MultiMap;
+import io.vertx.core.http.HttpMethod;
+import io.vertx.core.http.RequestOptions;
+import io.vertx.mutiny.core.Vertx;
+import io.vertx.mutiny.core.buffer.Buffer;
+import io.vertx.mutiny.core.http.HttpClient;
+import io.vertx.mutiny.core.http.HttpClientRequest;
+import io.vertx.mutiny.core.http.HttpClientResponse;
 
 @Singleton
 @Path("/client")
@@ -31,6 +40,12 @@ public interface PingPongRestClient {
     @RestClient
     PingPongRestClient pingRestClient;
 
+    @Inject
+    Vertx vertx;
+
+    @ConfigProperty(name = "test.url")
+    String testUrl;
+
     @GET
     @Path("pong/{message}")
     public String pong(@PathParam("message") String message) {
@@ -49,4 +64,21 @@ public String ping(@PathParam("message") String message) {
     public Uni<String> asyncPing(@PathParam("message") String message) {
         return pingRestClient.asyncPingpong(message);
     }
+
+    @GET
+    @Path("async-ping-named/{message}")
+    public Uni<String> asyncPingNamed(@PathParam("message") String message) {
+        HttpClient httpClient = vertx.createHttpClient();
+        RequestOptions options = new RequestOptions()
+                .setMethod(HttpMethod.GET)
+                .setAbsoluteURI(testUrl + "/client/pong/" + message)
+                .setHeaders(MultiMap.caseInsensitiveMultiMap())
+                .setTraceOperation("Async Ping");
+        return httpClient.request(options)
+                .flatMap(HttpClientRequest::send)
+                .flatMap(HttpClientResponse::body)
+                .map(Buffer::toString)
+                .onItemOrFailure().call(httpClient::close);
+    }
+
 }
diff --git a/integration-tests/opentelemetry/src/test/java/io/quarkus/it/opentelemetry/OpenTelemetryTestCase.java b/integration-tests/opentelemetry/src/test/java/io/quarkus/it/opentelemetry/OpenTelemetryTestCase.java
index 2a73f49d5c0d7..39964be7272de 100644
--- a/integration-tests/opentelemetry/src/test/java/io/quarkus/it/opentelemetry/OpenTelemetryTestCase.java
+++ b/integration-tests/opentelemetry/src/test/java/io/quarkus/it/opentelemetry/OpenTelemetryTestCase.java
@@ -753,6 +753,27 @@ void testTemplatedPathOnClass() {
         Assertions.assertNotNull(spanData.get("attr_http.user_agent"));
     }
 
+    @Test
+    void testCustomSpanNames() {
+        resetExporter();
+
+        given()
+                .contentType("application/json")
+                .when().get("/client/async-ping-named/one")
+                .then()
+                .statusCode(200)
+                .body(containsString("one"));
+
+        Awaitility.await().atMost(Duration.ofMinutes(2)).until(() -> getSpans().size() > 2);
+        Map<String, Object> spanData = getSpans().get(1);
+        Assertions.assertNotNull(spanData);
+        Assertions.assertNotNull(spanData.get("spanId"));
+
+        verifyResource(spanData);
+
+        Assertions.assertEquals("Async Ping", spanData.get("name"));
+    }
+
     /**
      * From bug #26149
      * NPE was thrown when HTTP version was not supported with OpenTelemetry