diff --git a/newsfragments/4360.removal.1.rst b/newsfragments/4360.removal.1.rst
new file mode 100644
index 0000000000..f00d6be518
--- /dev/null
+++ b/newsfragments/4360.removal.1.rst
@@ -0,0 +1,2 @@
+Remove deprecated ``setuptools.dep_util``.
+The provided alternative is ``setuptools.modified``.
diff --git a/setuptools/dep_util.py b/setuptools/dep_util.py
deleted file mode 100644
index 998ffa206e..0000000000
--- a/setuptools/dep_util.py
+++ /dev/null
@@ -1,16 +0,0 @@
-from ._distutils import _modified
-from .warnings import SetuptoolsDeprecationWarning
-
-
-def __getattr__(name):
-    if name not in ['newer_group', 'newer_pairwise_group']:
-        raise AttributeError(name)
-    SetuptoolsDeprecationWarning.emit(
-        "dep_util is Deprecated. Use functions from setuptools.modified instead.",
-        "Please use `setuptools.modified` instead of `setuptools.dep_util`.",
-        see_url="https://github.com/pypa/setuptools/pull/4069",
-        due_date=(2024, 5, 21),
-        # Warning added in v69.0.0 on 2023/11/20,
-        # See https://github.com/pypa/setuptools/discussions/4128
-    )
-    return getattr(_modified, name)