diff --git a/config/nrfconnect/chip-gn/BUILD.gn b/config/nrfconnect/chip-gn/BUILD.gn
index b9a71c9d34334d..63ddd225669d0d 100644
--- a/config/nrfconnect/chip-gn/BUILD.gn
+++ b/config/nrfconnect/chip-gn/BUILD.gn
@@ -19,22 +19,12 @@ import("${chip_root}/build/chip/tests.gni")
 
 assert(current_os == "zephyr")
 
-declare_args() {
-  chip_build_pw_rpc_lib = false
-}
-
 group("nrfconnect") {
   deps = [ "${chip_root}/src/lib" ]
 
   if (chip_build_tests) {
     deps += [ "${chip_root}/src:tests" ]
   }
-
-  # Building PW_RPC lib with GN may go obsolete after getting full CMake
-  # support in Pigweed.
-  if (chip_build_pw_rpc_lib) {
-    deps += [ "lib/pw_rpc" ]
-  }
 }
 
 group("default") {
diff --git a/config/nrfconnect/chip-gn/lib/pw_rpc/BUILD.gn b/config/nrfconnect/chip-gn/lib/pw_rpc/BUILD.gn
deleted file mode 100644
index e99ab14b29c454..00000000000000
--- a/config/nrfconnect/chip-gn/lib/pw_rpc/BUILD.gn
+++ /dev/null
@@ -1,40 +0,0 @@
-# Copyright (c) 2020 Project CHIP Authors
-#
-# Licensed under the Apache License, Version 2.0 (the "License");
-# you may not use this file except in compliance with the License.
-# You may obtain a copy of the License at
-#
-# http://www.apache.org/licenses/LICENSE-2.0
-#
-# Unless required by applicable law or agreed to in writing, software
-# distributed under the License is distributed on an "AS IS" BASIS,
-# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
-# See the License for the specific language governing permissions and
-# limitations under the License.
-
-import("//build_overrides/chip.gni")
-import("//build_overrides/pigweed.gni")
-import("$dir_pw_build/target_types.gni")
-
-static_library("pw_rpc") {
-  output_name = "libPwRpc"
-
-  sources = [ "${dir_pigweed}/pw_hdlc/rpc_example/hdlc_rpc_server.cc" ]
-
-  deps = [
-    "$dir_pw_rpc:server",
-    "$dir_pw_rpc/nanopb:echo_service",
-    "$dir_pw_rpc/system_server",
-    "${chip_root}/examples/platform/nrfconnect/pw_sys_io:pw_sys_io_nrfconnect",
-    "${dir_pigweed}/pw_hdlc:pw_rpc",
-    dir_pw_assert,
-    dir_pw_hdlc,
-    dir_pw_log,
-  ]
-
-  public_configs = [ "${dir_pigweed}/pw_hdlc:default_config" ]
-
-  output_dir = "${root_out_dir}/lib"
-
-  complete_static_lib = true
-}
diff --git a/config/nrfconnect/chip-gn/lib/pw_rpc/pw_rpc.gni b/config/nrfconnect/chip-gn/lib/pw_rpc/pw_rpc.gni
deleted file mode 100644
index 5732dca57cd060..00000000000000
--- a/config/nrfconnect/chip-gn/lib/pw_rpc/pw_rpc.gni
+++ /dev/null
@@ -1,30 +0,0 @@
-# Copyright (c) 2021 Project CHIP Authors
-#
-# Licensed under the Apache License, Version 2.0 (the "License");
-# you may not use this file except in compliance with the License.
-# You may obtain a copy of the License at
-#
-# http://www.apache.org/licenses/LICENSE-2.0
-#
-# Unless required by applicable law or agreed to in writing, software
-# distributed under the License is distributed on an "AS IS" BASIS,
-# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
-# See the License for the specific language governing permissions and
-# limitations under the License.
-
-import("//build_overrides/chip.gni")
-import("//build_overrides/pigweed.gni")
-
-pw_log_BACKEND = "$dir_pw_log_basic"
-pw_assert_BACKEND = "$dir_pw_assert_log"
-pw_sys_io_BACKEND =
-    "${chip_root}/examples/platform/nrfconnect/pw_sys_io:pw_sys_io_nrfconnect"
-pw_rpc_system_server_BACKEND =
-    "${chip_root}/examples/common/pigweed:system_rpc_server"
-
-pw_build_LINK_DEPS = [
-  "$dir_pw_assert:impl",
-  "$dir_pw_log:impl",
-]
-
-dir_pw_third_party_nanopb = "${chip_root}/third_party/nanopb/repo"
diff --git a/config/nrfconnect/chip-module/CMakeLists.txt b/config/nrfconnect/chip-module/CMakeLists.txt
index 4f9ce318cba0df..9a9ed9529afb41 100644
--- a/config/nrfconnect/chip-module/CMakeLists.txt
+++ b/config/nrfconnect/chip-module/CMakeLists.txt
@@ -121,10 +121,6 @@ if (NOT CHIP_LIBRARIES)
     set(CHIP_LIBRARIES -lCHIP)
 endif()
 
-if (CONFIG_CHIP_PW_RPC)
-    list(APPEND CHIP_LIBRARIES -lPwRpc)
-endif()
-
 # Set up CHIP project configuration file
 
 if (CONFIG_CHIP_PROJECT_CONFIG)
@@ -180,10 +176,6 @@ find_package(Python3 REQUIRED)
 # Generate configuration for CHIP GN build system
 # ==============================================================================
 
-if (CONFIG_CHIP_PW_RPC)
-    chip_gn_arg_import("${GN_ROOT_TARGET}/lib/pw_rpc/pw_rpc.gni")
-endif()
-
 chip_gn_arg_cflags("target_cflags"                          ${CHIP_CFLAGS})
 chip_gn_arg_cflags("target_cflags_c"                        ${CHIP_CFLAGS_C})
 chip_gn_arg_cflags("target_cflags_cc"                       ${CHIP_CFLAGS_CC})
@@ -202,7 +194,6 @@ chip_gn_arg_bool  ("chip_build_tests"                       CONFIG_CHIP_BUILD_TE
 chip_gn_arg_bool  ("chip_monolithic_tests"                  CONFIG_CHIP_BUILD_TESTS)
 chip_gn_arg_bool  ("chip_inet_config_enable_tcp_endpoint"   CONFIG_CHIP_BUILD_TESTS)
 chip_gn_arg_bool  ("chip_build_libshell"                    CONFIG_CHIP_LIB_SHELL)
-chip_gn_arg_bool  ("chip_build_pw_rpc_lib"                  CONFIG_CHIP_PW_RPC)
 
 if (CONFIG_CHIP_ENABLE_DNSSD_SRP)
     chip_gn_arg_string("chip_mdns" "platform")
diff --git a/examples/platform/nrfconnect/pw_sys_io/CMakeLists.txt b/examples/platform/nrfconnect/pw_sys_io/CMakeLists.txt
index 84b78c3ebd31ed..e71fbd808e29dc 100644
--- a/examples/platform/nrfconnect/pw_sys_io/CMakeLists.txt
+++ b/examples/platform/nrfconnect/pw_sys_io/CMakeLists.txt
@@ -4,6 +4,7 @@ add_library(suppress_zephyr_warnings INTERFACE)
 target_compile_options(suppress_zephyr_warnings INTERFACE
     -Wno-redundant-decls
     -Wno-missing-field-initializers
+    -Wno-cast-qual
 )
 
 pw_add_module_library(pw_sys_io.nrfconnect