diff --git a/.github/workflows/darwin.yaml b/.github/workflows/darwin.yaml
index 2d7443f9e9758c..a58617131a035d 100644
--- a/.github/workflows/darwin.yaml
+++ b/.github/workflows/darwin.yaml
@@ -105,19 +105,15 @@ jobs:
                   mkdir -p /tmp/darwin/framework-tests
                   ../../../out/debug/chip-all-clusters-app --interface-id -1 > >(tee /tmp/darwin/framework-tests/all-cluster-app.log) 2> >(tee /tmp/darwin/framework-tests/all-cluster-app-err.log >&2) &
                   ../../../out/debug/chip-all-clusters-app --interface-id -1 --dac_provider ../../../credentials/development/commissioner_dut/struct_cd_origin_pid_vid_correct/test_case_vector.json --product-id 32768 --discriminator 3839 --secured-device-port 5539 --KVS /tmp/chip-all-clusters-app-kvs2 > >(tee /tmp/darwin/framework-tests/all-cluster-app-origin-vid.log) 2> >(tee /tmp/darwin/framework-tests/all-cluster-app-origin-vid-err.log >&2) &
-                  # Disable BLE because the app does not have the permission to use
-                  # it and that may crash the CI.
-                  #
-                  # -enableUndefinedBehaviorSanitizer instruments the code in Matter.framework,
-                  # but to instrument the code in the underlying libCHIP we need to pass CHIP_IS_UBSAN=YES
-                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_UBSAN=YES CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1'> >(tee /tmp/darwin/framework-tests/darwin-tests-asan.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-err.log >&2)
+                  # Disable BLE (CHIP_IS_BLE=NO) because the app does not have the permission to use it and that may crash the CI.
+
+                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1'> >(tee /tmp/darwin/framework-tests/darwin-tests-asan.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-err.log >&2)
                   # And the same thing, but with MTR_PER_CONTROLLER_STORAGE_ENABLED turned off, so we test that it does not break for now.
-                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_UBSAN=YES CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1 MTR_PER_CONTROLLER_STORAGE_ENABLED=0' > >(tee /tmp/darwin/framework-tests/darwin-tests-asan-controller-storage.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-controller-storage-err.log >&2)
+                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1 MTR_PER_CONTROLLER_STORAGE_ENABLED=0' > >(tee /tmp/darwin/framework-tests/darwin-tests-asan-controller-storage.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-controller-storage-err.log >&2)
                   # And the same thing, but with MTR_NO_AVAILABILITY not turned on.  This requires -Wno-unguarded-availability-new to avoid availability errors.
-                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion -Wno-unguarded-availability-new' CHIP_IS_UBSAN=YES CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited}' > >(tee /tmp/darwin/framework-tests/darwin-tests-asan-with-availability-annotations.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-with-availability-annotations-err.log >&2)
-                  # -enableThreadSanitizer instruments the code in Matter.framework,
-                  # but to instrument the code in the underlying libCHIP we need to pass CHIP_IS_TSAN=YES
-                  xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableThreadSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_TSAN=YES CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1' > >(tee /tmp/darwin/framework-tests/darwin-tests-tsan.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-tsan-err.log >&2)
+                  TEST_RUNNER_ASAN_OPTIONS=__CURRENT_VALUE__:detect_stack_use_after_return=1 xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableAddressSanitizer YES -enableUndefinedBehaviorSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion -Wno-unguarded-availability-new' CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited}' > >(tee /tmp/darwin/framework-tests/darwin-tests-asan-with-availability-annotations.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-asan-with-availability-annotations-err.log >&2)
+
+                  xcodebuild test -target "Matter" -scheme "Matter Framework Tests" -sdk macosx -enableThreadSanitizer YES OTHER_CFLAGS='${inherited} -Werror -Wconversion' CHIP_IS_BLE=NO GCC_PREPROCESSOR_DEFINITIONS='${inherited} MTR_NO_AVAILABILITY=1' > >(tee /tmp/darwin/framework-tests/darwin-tests-tsan.log) 2> >(tee /tmp/darwin/framework-tests/darwin-tests-tsan-err.log >&2)
               working-directory: src/darwin/Framework
             - name: Build Matter TV Casting Bridge
               run: |
diff --git a/build/config/compiler/BUILD.gn b/build/config/compiler/BUILD.gn
index b6ad67a64944fd..7ada1348f797b4 100644
--- a/build/config/compiler/BUILD.gn
+++ b/build/config/compiler/BUILD.gn
@@ -395,11 +395,16 @@ declare_args() {
 }
 
 config("sanitize_address") {
+  defines = []
   cflags = [
     "-fsanitize=address",
     "-fno-omit-frame-pointer",
   ]
   ldflags = cflags
+
+  if (target_os == "mac" || target_os == "ios") {
+    defines += [ "_LIBCPP_HAS_NO_ASAN" ]
+  }
 }
 
 config("sanitize_thread") {
diff --git a/src/darwin/Framework/chip_xcode_build_connector.sh b/src/darwin/Framework/chip_xcode_build_connector.sh
index 3ab0464bb79482..e802e99cd0cfcd 100755
--- a/src/darwin/Framework/chip_xcode_build_connector.sh
+++ b/src/darwin/Framework/chip_xcode_build_connector.sh
@@ -132,19 +132,19 @@ esac
     )
 }
 
-[[ $CHIP_IS_ASAN == YES ]] && {
+[[ $CHIP_IS_ASAN == YES || $ENABLE_ADDRESS_SANITIZER == YES ]] && {
     args+=(
         'is_asan=true'
     )
 }
 
-[[ $CHIP_IS_UBSAN == YES ]] && {
+[[ $CHIP_IS_UBSAN == YES || $ENABLE_UNDEFINED_BEHAVIOR_SANITIZER == YES ]] && {
     args+=(
         'is_ubsan=true'
     )
 }
 
-[[ $CHIP_IS_TSAN == YES ]] && {
+[[ $CHIP_IS_TSAN == YES || $ENABLE_THREAD_SANITIZER == YES ]] && {
     args+=(
         'is_tsan=true'
         # The system stats stuff races on the stats in various ways,