diff --git a/scripts/tests/chiptest/test_definition.py b/scripts/tests/chiptest/test_definition.py
index bbce2428b619a9..a655fa894eb3c9 100644
--- a/scripts/tests/chiptest/test_definition.py
+++ b/scripts/tests/chiptest/test_definition.py
@@ -279,6 +279,13 @@ def Run(self, runner, apps_register, paths: ApplicationPaths, pics_file: str,
                 if path == paths.chip_tool or path == paths.chip_repl_yaml_tester_cmd or path == paths.chip_tool_with_python_cmd:
                     continue
 
+                # Skip items where we don't actually have a path.  This can
+                # happen if the relevant application does not exist.  It's
+                # non-fatal as long as we are not trying to run any tests that
+                # need that application.
+                if len(path) == 1 and path[0] is None:
+                    continue
+
                 # For the app indicated by self.target, give it the 'default' key to add to the register
                 if path == target_app:
                     key = 'default'