1144 smcpp.commands.command DEBUG ['/build/Cellar/python/3.6.5/bin/smc++', 'estimate', '--cores', '8', '--timepoints', '10,300000', '-o', 'aro/', '6.5e-9', '../smcpp_02/input/aro.chr01.smc.gz', '../smcpp_02/input/aro.chr02.smc.gz', '../smcpp_02/input/aro.chr03.smc.gz', '../smcpp_02/input/aro.chr04.smc.gz', '../smcpp_02/input/aro.chr05.smc.gz', '../smcpp_02/input/aro.chr06.smc.gz', '../smcpp_02/input/aro.chr07.smc.gz', '../smcpp_02/input/aro.chr08.smc.gz', '../smcpp_02/input/aro.chr09.smc.gz', '../smcpp_02/input/aro.chr10.smc.gz', '../smcpp_02/input/aro.chr11.smc.gz', '../smcpp_02/input/aro.chr12.smc.gz'] 1144 smcpp.commands.command DEBUG Namespace(algorithm='Powell', command='estimate', cores=8, data=['../smcpp_02/input/aro.chr01.smc.gz', '../smcpp_02/input/aro.chr02.smc.gz', '../smcpp_02/input/aro.chr03.smc.gz', '../smcpp_02/input/aro.chr04.smc.gz', '../smcpp_02/input/aro.chr05.smc.gz', '../smcpp_02/input/aro.chr06.smc.gz', '../smcpp_02/input/aro.chr07.smc.gz', '../smcpp_02/input/aro.chr08.smc.gz', '../smcpp_02/input/aro.chr09.smc.gz', '../smcpp_02/input/aro.chr10.smc.gz', '../smcpp_02/input/aro.chr11.smc.gz', '../smcpp_02/input/aro.chr12.smc.gz'], em_iterations=20, ftol=0.0001, hs=2, initial_model=None, knots=8, lambda_=None, length_cutoff=None, mu=6.5e-09, no_initialize=False, no_multi=False, nonseg_cutoff=None, outdir='aro/', polarization_error=0.5, r=None, regularization_degree=1, regularization_penalty=6, seed=0, spline='piecewise', thinning=None, timepoints='10,300000', unfold=False, verbose=0, w=100, xtol=0.1) 1144 smcpp.analysis.base INFO theta: 0.000100 1145 smcpp.analysis.base INFO rho: 0.000100 1145 smcpp.analysis.base DEBUG Polarization error p=0.500000 1145 smcpp.analysis.base DEBUG regularization degree=1 1146 smcpp.data_filter DEBUG LoadData() 1146 smcpp.data_filter INFO Loading data... 2194 smcpp.data_filter INFO 0.38 Gb of data 2196 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[248, 0, 0, 30], [ 1, 0, 0, 28], [ 5, 0, 0, 30], ..., [ 5, 0, 0, 30], [ 1, 0, 0, 22], [394, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr03.smc.gz') 2196 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[ 52, 0, 0, 30], [ 1, -1, 5, 11], [ 29, 0, 0, 30], ..., [ 1, 0, 0, 30], [ 1, 0, 0, 28], [332, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr12.smc.gz') 2197 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[253, 0, 0, 30], [ 1, -1, 6, 27], [ 56, 0, 0, 30], ..., [ 8, 0, 0, 30], [ 1, 0, 0, 26], [264, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr06.smc.gz') 2198 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[ 12, 0, 0, 30], [ 1, 0, 0, 26], [228, 0, 0, 30], ..., [368, 0, 0, 30], [ 1, 2, 21, 30], [157, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr11.smc.gz') 2198 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[127, 0, 0, 30], [ 1, 0, 0, 24], [ 2, 0, 0, 30], ..., [212, 0, 0, 30], [ 2, 0, 0, 26], [ 28, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr01.smc.gz') 2199 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[156, 0, 0, 30], [ 1, -1, 0, 0], [743, 0, 0, 30], ..., [113, 0, 0, 30], [ 1, 0, 2, 28], [380, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr04.smc.gz') 2200 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[433, 0, 0, 30], [ 1, 0, 0, 26], [ 31, 0, 0, 30], ..., [235, 0, 0, 30], [ 1, -1, 0, 1], [ 31, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr05.smc.gz') 2200 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[176, 0, 0, 30], [ 1, 0, 0, 28], [ 1, 0, 0, 30], ..., [ 13, 0, 0, 30], [ 1, -1, 0, 0], [750, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr07.smc.gz') 2201 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[537, 0, 0, 30], [ 1, -1, 1, 1], [ 2, 0, 0, 30], ..., [438, 0, 0, 30], [ 1, 0, 6, 30], [476, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr10.smc.gz') 2201 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[558, 0, 0, 30], [ 1, 0, 0, 28], [ 15, 0, 0, 30], ..., [ 23, 0, 0, 30], [ 1, -1, 0, 21], [398, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr02.smc.gz') 2202 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[ 1, 0, 0, 30], [10000, -1, 0, 0], [ 1, 0, 0, 30], ..., [ 5583, 0, 0, 30], [ 1, -1, 0, 0], [32006, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr09.smc.gz') 2202 smcpp.data_filter DEBUG Contig(pid=('aro',), data=array([[357, 0, 0, 30], [ 1, -1, 1, 5], [ 48, 0, 0, 30], ..., [ 33, 0, 0, 30], [ 1, -1, 0, 0], [ 7, 0, 0, 30]], dtype=int32), n=array([30]), a=array([2]), fn='../smcpp_02/input/aro.chr08.smc.gz') 2203 smcpp.data_filter INFO 1 population 2203 smcpp.data_filter DEBUG RecodeNonseg(cutoff=None) 2274 smcpp.data_filter DEBUG Compress() 6472 smcpp.data_filter DEBUG BreakLongSpans(cutoff=100000) 6876 smcpp.data_filter DEBUG DropSmallContigs(cutoff=100000) 6905 smcpp.data_filter DEBUG Watterson() 7731 smcpp.data_filter DEBUG sites: 2082148/1489537889 watterson:0.001398 7731 smcpp.data_filter DEBUG CountMutations(w=153846) 7776 smcpp.data_filter DEBUG mutation counts in 153846bp windows: min=0 .05=5 .95=859 max=1980 7777 smcpp.data_filter DEBUG Compress() 10878 smcpp.data_filter DEBUG Thin(thinning=None) 10879 smcpp.data_filter DEBUG Thinning interval: 3465 10880 smcpp.data_filter DEBUG Thinning interval: 3465 10881 smcpp.data_filter DEBUG Thinning interval: 3465 10881 smcpp.data_filter DEBUG Thinning interval: 3465 10881 smcpp.data_filter DEBUG Thinning interval: 3465 10882 smcpp.data_filter DEBUG Thinning interval: 3465 10882 smcpp.data_filter DEBUG Thinning interval: 3465 10883 smcpp.data_filter DEBUG Thinning interval: 3465 10884 smcpp.data_filter DEBUG Thinning interval: 3465 10885 smcpp.data_filter DEBUG Thinning interval: 3465 10886 smcpp.data_filter DEBUG Thinning interval: 3465 10886 smcpp.data_filter DEBUG Thinning interval: 3465 10961 smcpp.data_filter DEBUG BinObservations(w=100) 11016 smcpp.data_filter DEBUG RecodeMonomorphic() 11039 smcpp.data_filter DEBUG Compress() 13747 smcpp.data_filter DEBUG Validate() 16096 smcpp.data_filter DEBUG DropUninformativeContigs() 16101 smcpp.data_filter DEBUG Summarize() 16101 smcpp.data_filter DEBUG [[34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30]] 16102 smcpp.data_filter DEBUG [[34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30]] 16103 smcpp.data_filter DEBUG [[ 5 0 0 0] [ 2 1 0 0] [ 4 0 0 0] [ 1 1 0 0] [13 0 0 0] [ 1 1 0 0] [ 8 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30]] 16103 smcpp.data_filter DEBUG [[ 5 0 0 0] [ 2 1 0 0] [ 6 0 0 0] [ 6 1 0 0] [15 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30]] 16104 smcpp.data_filter DEBUG [[4 0 0 0] [2 1 0 0] [1 0 0 0] [1 1 0 0] [1 0 0 0] [2 1 0 0] [1 0 0 0] [1 1 0 0] [1 0 0 0] [1 1 0 0]] 16104 smcpp.data_filter DEBUG [[34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30]] 16105 smcpp.data_filter DEBUG [[34 0 0 0] [ 1 0 0 30] [14 0 0 0] [ 1 1 0 0] [ 2 0 0 0] [ 3 1 0 0] [ 2 0 0 0] [ 1 1 0 0] [ 9 0 0 0] [ 2 1 0 0]] 16105 smcpp.data_filter DEBUG [[ 6 0 0 0] [ 1 1 0 0] [27 0 0 0] [ 1 0 0 26] [34 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30] [27 0 0 0] [ 1 1 0 0]] 16106 smcpp.data_filter DEBUG [[7 0 0 0] [3 1 0 0] [3 0 0 0] [1 1 0 0] [1 0 0 0] [7 1 0 0] [5 0 0 0] [2 1 0 0] [2 0 0 0] [1 1 0 0]] 16106 smcpp.data_filter DEBUG [[5 0 0 0] [1 1 0 0] [1 0 0 0] [1 1 0 0] [3 0 0 0] [1 1 0 0] [7 0 0 0] [1 1 0 0] [4 0 0 0] [1 1 0 0]] 16107 smcpp.data_filter DEBUG [[ 1 0 0 0] [99 -1 0 0] [ 1 0 0 0] [99 -1 0 0] [ 1 0 0 0] [99 -1 0 0] [11 0 0 0] [ 1 0 0 30] [34 0 0 0] [ 1 0 0 30]] 16107 smcpp.data_filter DEBUG [[29 0 0 0] [ 1 1 0 0] [ 4 0 0 0] [ 1 0 0 30] [ 3 0 0 0] [ 1 1 0 0] [30 0 0 0] [ 1 0 0 30] [33 0 0 0] [ 1 0 0 30]] 16108 smcpp.analysis.analysis DEBUG Knots are: [0.00065 0.00235805 0.00855448 0.03103372 0.1125833 0.40842671 1.48167959 5.37519785] 16109 smcpp.analysis.analysis DEBUG hidden states in coalescent scaling: [0. 0.00065 0.00235805 0.00855448 0.03103372 0.1125833 0.40842671 1.48167959 5.37519785 inf] 16110 smcpp.analysis.analysis DEBUG knots in coalescent scaling: [0.00065 0.00235805 0.00855448 0.03103372 0.1125833 0.40842671 1.48167959 5.37519785] 16110 smcpp.analysis.base DEBUG Creating inference manager... 16111 smcpp.analysis.base DEBUG Creating inference manager for ('aro',) 16623 smcpp.model DEBUG model before randomization: [2.63751922 2.63751922 2.63751922 2.63751922 2.63751922 2.63751922 2.63751922 2.63751922] 16626 smcpp.model DEBUG model after randomization: [2.63769562 2.63755923 2.63761709 2.63774331 2.63770597 2.63742149 2.63761422 2.63750408] 16972 smcpp._smcpp DEBUG im(('aro',)).q1: 0.0 16973 smcpp._smcpp DEBUG im(('aro',)).q2: -1325456.8 16973 smcpp._smcpp DEBUG im(('aro',)).q3: -5922.2 16973 smcpp._smcpp DEBUG im(('aro',)).q4: 0.0 16975 smcpp.model DEBUG r1:0.000945 r2:0.000671 16976 smcpp.analysis.base DEBUG reg: 0.0 [] 16976 smcpp.analysis.base DEBUG Q: -1331379.0 [] 16976 smcpp.analysis.analysis DEBUG Regularization penalty: lambda=1.33138 16977 smcpp.optimize.plugins.progress_printer INFO Starting EM algorithm... 16977 smcpp.optimize.plugins.progress_printer INFO EM iteration 1 of 20... 16977 smcpp.analysis.base INFO Running E-step 18590 smcpp.analysis.base INFO E-step completed 18605 smcpp.model DEBUG r1:0.000945 r2:0.000671 18605 smcpp.optimize.plugins.loglikelihood_monitor INFO Loglik: -678978.832221 18892 smcpp._smcpp DEBUG im(('aro',)).q1: -2.1 18892 smcpp._smcpp DEBUG im(('aro',)).q2: -646333.0 18893 smcpp._smcpp DEBUG im(('aro',)).q3: -4755.3 18893 smcpp._smcpp DEBUG im(('aro',)).q4: -51840.5 18895 smcpp.model DEBUG r1:0.000945 r2:0.000671 18895 smcpp.analysis.base DEBUG reg: 0.0 [] 18896 smcpp.analysis.base DEBUG Q: -702930.9 [] 18896 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(-0.236068)=-702930.923510 19180 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 19181 smcpp._smcpp DEBUG im(('aro',)).q2: -633126.1 19181 smcpp._smcpp DEBUG im(('aro',)).q3: -5134.0 19181 smcpp._smcpp DEBUG im(('aro',)).q4: -52505.2 19183 smcpp.model DEBUG r1:0.000945 r2:0.000671 19183 smcpp.analysis.base DEBUG reg: 0.0 [] 19184 smcpp.analysis.base DEBUG Q: -690767.0 [] 19184 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.236068)=-690766.960976 19474 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 19475 smcpp._smcpp DEBUG im(('aro',)).q2: -639605.8 19475 smcpp._smcpp DEBUG im(('aro',)).q3: -5527.3 19475 smcpp._smcpp DEBUG im(('aro',)).q4: -53029.2 19477 smcpp.model DEBUG r1:0.000945 r2:0.000671 19477 smcpp.analysis.base DEBUG reg: 0.0 [] 19478 smcpp.analysis.base DEBUG Q: -698163.9 [] 19478 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.527864)=-698163.854552 19768 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 19768 smcpp._smcpp DEBUG im(('aro',)).q2: -633321.9 19768 smcpp._smcpp DEBUG im(('aro',)).q3: -5087.2 19769 smcpp._smcpp DEBUG im(('aro',)).q4: -52433.5 19770 smcpp.model DEBUG r1:0.000945 r2:0.000671 19771 smcpp.analysis.base DEBUG reg: 0.0 [] 19771 smcpp.analysis.base DEBUG Q: -690844.3 [] 19771 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.192530)=-690844.306322 20067 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 20068 smcpp._smcpp DEBUG im(('aro',)).q2: -633150.3 20068 smcpp._smcpp DEBUG im(('aro',)).q3: -5122.1 20068 smcpp._smcpp DEBUG im(('aro',)).q4: -52487.2 20070 smcpp.model DEBUG r1:0.000945 r2:0.000671 20070 smcpp.analysis.base DEBUG reg: 0.0 [] 20071 smcpp.analysis.base DEBUG Q: -690761.4 [] 20071 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.225280)=-690761.388800 20360 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 20360 smcpp._smcpp DEBUG im(('aro',)).q2: -633145.4 20361 smcpp._smcpp DEBUG im(('aro',)).q3: -5124.0 20361 smcpp._smcpp DEBUG im(('aro',)).q4: -52490.1 20362 smcpp.model DEBUG r1:0.000945 r2:0.000671 20363 smcpp.analysis.base DEBUG reg: 0.0 [] 20363 smcpp.analysis.base DEBUG Q: -690761.2 [] 20364 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.226985)=-690761.167005 20654 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 20655 smcpp._smcpp DEBUG im(('aro',)).q2: -633145.2 20655 smcpp._smcpp DEBUG im(('aro',)).q3: -5124.1 20655 smcpp._smcpp DEBUG im(('aro',)).q4: -52490.2 20657 smcpp.model DEBUG r1:0.000945 r2:0.000671 20657 smcpp.analysis.base DEBUG reg: 0.0 [] 20658 smcpp.analysis.base DEBUG Q: -690761.2 [] 20658 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.227046)=-690761.166711 20946 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 20947 smcpp._smcpp DEBUG im(('aro',)).q2: -633145.2 20947 smcpp._smcpp DEBUG im(('aro',)).q3: -5124.1 20947 smcpp._smcpp DEBUG im(('aro',)).q4: -52490.2 20948 smcpp.model DEBUG r1:0.000945 r2:0.000671 20949 smcpp.analysis.base DEBUG reg: 0.0 [] 20949 smcpp.analysis.base DEBUG Q: -690761.2 [] 20950 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.227050)=-690761.166710 21239 smcpp._smcpp DEBUG im(('aro',)).q1: -1.7 21239 smcpp._smcpp DEBUG im(('aro',)).q2: -633145.2 21240 smcpp._smcpp DEBUG im(('aro',)).q3: -5124.1 21240 smcpp._smcpp DEBUG im(('aro',)).q4: -52490.2 21241 smcpp.model DEBUG r1:0.000945 r2:0.000671 21242 smcpp.analysis.base DEBUG reg: 0.0 [] 21242 smcpp.analysis.base DEBUG Q: -690761.2 [] 21242 smcpp.optimize.plugins.scale_optimizer DEBUG scale Q(0.227053)=-690761.166711 21244 smcpp.optimize.plugins.parameter_optimizer INFO Updating rho, bounds (0.000001, 0.010000) 21529 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21530 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21530 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21530 smcpp._smcpp DEBUG im(('aro',)).q4: -52890.2 21532 smcpp.model DEBUG r1:0.000945 r2:0.000671 21532 smcpp.analysis.base DEBUG reg: 0.0 [] 21533 smcpp.analysis.base DEBUG Q: -694834.5 [] 21533 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.000100)=694834.504855 21533 smcpp.optimize.plugins.parameter_optimizer DEBUG Old rho: Q(0.000100)=694834.504855 21552 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21553 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21553 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21554 smcpp._smcpp DEBUG im(('aro',)).q4: -43664.8 21555 smcpp.model DEBUG r1:0.000945 r2:0.000671 21556 smcpp.analysis.base DEBUG reg: 0.0 [] 21556 smcpp.analysis.base DEBUG Q: -685609.2 [] 21556 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.003820)=685609.188612 21576 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21576 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21576 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21576 smcpp._smcpp DEBUG im(('aro',)).q4: -46891.7 21578 smcpp.model DEBUG r1:0.000945 r2:0.000671 21579 smcpp.analysis.base DEBUG reg: 0.0 [] 21579 smcpp.analysis.base DEBUG Q: -688836.1 [] 21579 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.006181)=688836.076623 21598 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21599 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21599 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21599 smcpp._smcpp DEBUG im(('aro',)).q4: -42578.8 21601 smcpp.model DEBUG r1:0.000945 r2:0.000671 21601 smcpp.analysis.base DEBUG reg: 0.0 [] 21602 smcpp.analysis.base DEBUG Q: -684523.2 [] 21602 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002361)=684523.197097 21621 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21622 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21622 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21622 smcpp._smcpp DEBUG im(('aro',)).q4: -44202.9 21624 smcpp.model DEBUG r1:0.000945 r2:0.000671 21624 smcpp.analysis.base DEBUG reg: 0.0 [] 21624 smcpp.analysis.base DEBUG Q: -686147.2 [] 21625 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.000808)=686147.243349 21644 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21644 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21644 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21645 smcpp._smcpp DEBUG im(('aro',)).q4: -42612.2 21646 smcpp.model DEBUG r1:0.000945 r2:0.000671 21647 smcpp.analysis.base DEBUG reg: 0.0 [] 21647 smcpp.analysis.base DEBUG Q: -684556.6 [] 21647 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002464)=684556.572864 21667 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21667 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21667 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21668 smcpp._smcpp DEBUG im(('aro',)).q4: -42561.4 21669 smcpp.model DEBUG r1:0.000945 r2:0.000671 21670 smcpp.analysis.base DEBUG reg: 0.0 [] 21670 smcpp.analysis.base DEBUG Q: -684505.8 [] 21670 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.001889)=684505.763935 21690 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21690 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21690 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21691 smcpp._smcpp DEBUG im(('aro',)).q4: -42802.1 21692 smcpp.model DEBUG r1:0.000945 r2:0.000671 21693 smcpp.analysis.base DEBUG reg: 0.0 [] 21693 smcpp.analysis.base DEBUG Q: -684746.4 [] 21693 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.001476)=684746.426207 21712 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21713 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21713 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21713 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.4 21715 smcpp.model DEBUG r1:0.000945 r2:0.000671 21715 smcpp.analysis.base DEBUG reg: 0.0 [] 21715 smcpp.analysis.base DEBUG Q: -684482.7 [] 21716 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002088)=684482.710881 21735 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21735 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21735 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21736 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.4 21737 smcpp.model DEBUG r1:0.000945 r2:0.000671 21738 smcpp.analysis.base DEBUG reg: 0.0 [] 21738 smcpp.analysis.base DEBUG Q: -684482.7 [] 21738 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002092)=684482.740395 21758 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21758 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21758 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21759 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 21760 smcpp.model DEBUG r1:0.000945 r2:0.000671 21761 smcpp.analysis.base DEBUG reg: 0.0 [] 21761 smcpp.analysis.base DEBUG Q: -684482.7 [] 21761 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002084)=684482.698484 21780 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 21781 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 21781 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 21781 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.4 21783 smcpp.model DEBUG r1:0.000945 r2:0.000671 21783 smcpp.analysis.base DEBUG reg: 0.0 [] 21783 smcpp.analysis.base DEBUG Q: -684482.7 [] 21784 smcpp.optimize.plugins.parameter_optimizer DEBUG rho f(0.002081)=684482.703274 21784 smcpp.optimize.plugins.parameter_optimizer INFO New rho: 0.00208413 21785 smcpp.optimize.plugins.progress_printer DEBUG Optimizing coordinates range(0, 8) 21785 smcpp.optimize.optimizers DEBUG bounds: [[0.09179907233816831 6.091799072338168] [0.09166268282440893 6.091662682824409] [0.09172054090198234 6.091720540901982] [0.09184675642349216 6.091846756423492] [0.0918094229025872 6.091809422902587] [0.09152493931558414 6.091524939315584] [0.09171767594532465 6.091717675945325] [0.09160753138274202 6.091607531382742]] 21786 smcpp.optimize.optimizers DEBUG x: 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 22081 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 22081 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 22082 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 22082 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 22100 smcpp.model DEBUG r1:0.000945 r2:0.000671 22101 smcpp.analysis.base DEBUG reg: 0.0 [] 22101 smcpp.analysis.base DEBUG Q: -684482.7 [] 22102 py.warnings WARNING /build/Cellar/python/3.6.5/lib/python3.6/site-packages/scipy/optimize/_minimize.py:415: RuntimeWarning: Method Powell does not use gradient information (jac). RuntimeWarning) 22103 py.warnings WARNING /build/Cellar/python/3.6.5/lib/python3.6/site-packages/scipy/optimize/_minimize.py:430: RuntimeWarning: Method Powell cannot handle constraints nor bounds. RuntimeWarning) 22103 smcpp.optimize.optimizers DEBUG x: 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 22395 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 22395 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 22396 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 22396 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 22414 smcpp.model DEBUG r1:0.000945 r2:0.000671 22414 smcpp.analysis.base DEBUG reg: 0.0 [] 22415 smcpp.analysis.base DEBUG Q: -684482.7 [] 22415 smcpp.optimize.optimizers DEBUG x: 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 22708 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 22708 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 22709 smcpp._smcpp DEBUG im(('aro',)).q3: -5413.6 22709 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 22727 smcpp.model DEBUG r1:0.000945 r2:0.000671 22728 smcpp.analysis.base DEBUG reg: 0.0 [] 22728 smcpp.analysis.base DEBUG Q: -684482.7 [] 22729 smcpp.optimize.optimizers DEBUG x: 4.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 23024 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 23025 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 23025 smcpp._smcpp DEBUG im(('aro',)).q3: -5414.1 23025 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 23043 smcpp.model DEBUG r1:1.000945 r2:1.000194 23044 smcpp.analysis.base DEBUG reg: 1.3 [] 23044 smcpp.analysis.base DEBUG Q: -684484.6 [] 23045 smcpp.optimize.optimizers DEBUG x: 1.474, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 23338 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 23338 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 23338 smcpp._smcpp DEBUG im(('aro',)).q3: -5410.1 23339 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 23356 smcpp.model DEBUG r1:1.618706 r2:1.617840 23357 smcpp.analysis.base DEBUG reg: 2.2 [] 23357 smcpp.analysis.base DEBUG Q: -684481.4 [] 23358 smcpp.optimize.optimizers DEBUG x: 1.270, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 23650 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 23650 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 23650 smcpp._smcpp DEBUG im(('aro',)).q3: -5409.1 23651 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 23668 smcpp.model DEBUG r1:1.822199 r2:1.821333 23669 smcpp.analysis.base DEBUG reg: 2.4 [] 23670 smcpp.analysis.base DEBUG Q: -684480.7 [] 23670 smcpp.optimize.optimizers DEBUG x: 0.941, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 23963 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 23963 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 23963 smcpp._smcpp DEBUG im(('aro',)).q3: -5407.1 23964 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 23981 smcpp.model DEBUG r1:2.151457 r2:2.150591 23982 smcpp.analysis.base DEBUG reg: 2.9 [] 23983 smcpp.analysis.base DEBUG Q: -684479.1 [] 23983 smcpp.optimize.optimizers DEBUG x: 0.408, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 24276 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 24276 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 24277 smcpp._smcpp DEBUG im(('aro',)).q3: -5402.0 24277 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 24294 smcpp.model DEBUG r1:2.684208 r2:2.683342 24295 smcpp.analysis.base DEBUG reg: 3.6 [] 24295 smcpp.analysis.base DEBUG Q: -684474.7 [] 24296 smcpp.optimize.optimizers DEBUG x: -0.454, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 24588 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 24588 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 24589 smcpp._smcpp DEBUG im(('aro',)).q3: -5385.8 24589 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.3 24606 smcpp.model DEBUG r1:3.546217 r2:3.545351 24607 smcpp.analysis.base DEBUG reg: 4.7 [] 24608 smcpp.analysis.base DEBUG Q: -684459.6 [] 24608 smcpp.optimize.optimizers DEBUG x: -1.849, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 24900 smcpp._smcpp DEBUG im(('aro',)).q1: -1.6 24901 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 24901 smcpp._smcpp DEBUG im(('aro',)).q3: -5311.7 24901 smcpp._smcpp DEBUG im(('aro',)).q4: -42538.4 24919 smcpp.model DEBUG r1:4.940977 r2:4.940111 24920 smcpp.analysis.base DEBUG reg: 6.6 [] 24920 smcpp.analysis.base DEBUG Q: -684387.5 [] 24921 smcpp.optimize.optimizers DEBUG x: -4.105, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 25212 smcpp._smcpp DEBUG im(('aro',)).q1: -2.0 25212 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 25213 smcpp._smcpp DEBUG im(('aro',)).q3: -4923.5 25213 smcpp._smcpp DEBUG im(('aro',)).q4: -42539.5 25230 smcpp.model DEBUG r1:7.197746 r2:7.196880 25231 smcpp.analysis.base DEBUG reg: 9.6 [] 25232 smcpp.analysis.base DEBUG Q: -684003.8 [] 25232 smcpp.optimize.optimizers DEBUG x: -7.757, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 25576 smcpp._smcpp DEBUG im(('aro',)).q1: -17.8 25576 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 25577 smcpp._smcpp DEBUG im(('aro',)).q3: -5390.5 25577 smcpp._smcpp DEBUG im(('aro',)).q4: -42547.6 25595 smcpp.model DEBUG r1:10.849275 r2:10.848409 25596 smcpp.analysis.base DEBUG reg: 14.4 [] 25596 smcpp.analysis.base DEBUG Q: -684499.5 [] 25596 smcpp.optimize.optimizers DEBUG x: -4.105, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 25925 smcpp._smcpp DEBUG im(('aro',)).q1: -2.0 25926 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 25926 smcpp._smcpp DEBUG im(('aro',)).q3: -4923.5 25927 smcpp._smcpp DEBUG im(('aro',)).q4: -42539.5 25944 smcpp.model DEBUG r1:7.197746 r2:7.196880 25945 smcpp.analysis.base DEBUG reg: 9.6 [] 25946 smcpp.analysis.base DEBUG Q: -684003.8 [] 25946 smcpp.optimize.optimizers DEBUG x: -5.500, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 26277 smcpp._smcpp DEBUG im(('aro',)).q1: -3.3 26278 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 26278 smcpp._smcpp DEBUG im(('aro',)).q3: -4604.2 26278 smcpp._smcpp DEBUG im(('aro',)).q4: -42542.3 26296 smcpp.model DEBUG r1:8.592506 r2:8.591640 26297 smcpp.analysis.base DEBUG reg: 11.4 [] 26297 smcpp.analysis.base DEBUG Q: -683690.4 [] 26298 smcpp.optimize.optimizers DEBUG x: -6.362, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 26629 smcpp._smcpp DEBUG im(('aro',)).q1: -5.6 26629 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 26630 smcpp._smcpp DEBUG im(('aro',)).q3: -4660.4 26630 smcpp._smcpp DEBUG im(('aro',)).q4: -42544.9 26647 smcpp.model DEBUG r1:9.454515 r2:9.453649 26648 smcpp.analysis.base DEBUG reg: 12.6 [] 26649 smcpp.analysis.base DEBUG Q: -683752.7 [] 26649 smcpp.optimize.optimizers DEBUG x: -5.657, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 26981 smcpp._smcpp DEBUG im(('aro',)).q1: -3.6 26981 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 26982 smcpp._smcpp DEBUG im(('aro',)).q3: -4582.3 26982 smcpp._smcpp DEBUG im(('aro',)).q4: -42542.7 27000 smcpp.model DEBUG r1:8.749119 r2:8.748252 27001 smcpp.analysis.base DEBUG reg: 11.6 [] 27001 smcpp.analysis.base DEBUG Q: -683669.4 [] 27001 smcpp.optimize.optimizers DEBUG x: -5.808, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 27333 smcpp._smcpp DEBUG im(('aro',)).q1: -3.9 27334 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 27334 smcpp._smcpp DEBUG im(('aro',)).q3: -4570.3 27334 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 27352 smcpp.model DEBUG r1:8.900059 r2:8.899192 27353 smcpp.analysis.base DEBUG reg: 11.8 [] 27353 smcpp.analysis.base DEBUG Q: -683658.4 [] 27353 smcpp.optimize.optimizers DEBUG x: -6.019, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 27686 smcpp._smcpp DEBUG im(('aro',)).q1: -4.4 27686 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 27687 smcpp._smcpp DEBUG im(('aro',)).q3: -4575.5 27687 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.8 27704 smcpp.model DEBUG r1:9.111842 r2:9.110976 27705 smcpp.analysis.base DEBUG reg: 12.1 [] 27705 smcpp.analysis.base DEBUG Q: -683665.1 [] 27706 smcpp.optimize.optimizers DEBUG x: -5.897, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 28037 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 28038 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 28038 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 28038 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.5 28056 smcpp.model DEBUG r1:8.989052 r2:8.988186 28056 smcpp.analysis.base DEBUG reg: 12.0 [] 28057 smcpp.analysis.base DEBUG Q: -683657.6 [] 28057 smcpp.optimize.optimizers DEBUG x: -5.897, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 28387 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 28388 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 28388 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 28388 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.5 28406 smcpp.model DEBUG r1:8.989052 r2:8.988186 28407 smcpp.analysis.base DEBUG reg: 12.0 [] 28407 smcpp.analysis.base DEBUG Q: -683657.6 [] 28407 smcpp.optimize.optimizers DEBUG x: -5.897, 4.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 28738 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 28739 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 28739 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 28739 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.5 28757 smcpp.model DEBUG r1:10.988937 r2:11.033602 28758 smcpp.analysis.base DEBUG reg: 14.6 [] 28758 smcpp.analysis.base DEBUG Q: -683660.3 [] 28758 smcpp.optimize.optimizers DEBUG x: -5.897, 1.474, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 29089 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 29090 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 29090 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 29090 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 29108 smcpp.model DEBUG r1:8.989052 r2:5.975339 29109 smcpp.analysis.base DEBUG reg: 12.0 [] 29109 smcpp.analysis.base DEBUG Q: -683657.6 [] 29109 smcpp.optimize.optimizers DEBUG x: -5.897, 2.276, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 29441 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 29441 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 29441 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 29442 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 29459 smcpp.model DEBUG r1:8.989052 r2:7.401513 29460 smcpp.analysis.base DEBUG reg: 12.0 [] 29460 smcpp.analysis.base DEBUG Q: -683657.6 [] 29461 smcpp.optimize.optimizers DEBUG x: -5.897, -1.144, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 29792 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 29792 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 29793 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.3 29793 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.9 29811 smcpp.model DEBUG r1:8.989052 r2:4.267318 29812 smcpp.analysis.base DEBUG reg: 12.0 [] 29812 smcpp.analysis.base DEBUG Q: -683658.5 [] 29813 smcpp.optimize.optimizers DEBUG x: -5.897, 1.474, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 30143 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 30144 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 30144 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 30145 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 30162 smcpp.model DEBUG r1:8.989052 r2:5.975339 30163 smcpp.analysis.base DEBUG reg: 12.0 [] 30163 smcpp.analysis.base DEBUG Q: -683657.6 [] 30164 smcpp.optimize.optimizers DEBUG x: -5.897, 0.474, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 30494 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 30494 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 30495 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 30495 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 30512 smcpp.model DEBUG r1:8.989052 r2:4.575165 30513 smcpp.analysis.base DEBUG reg: 12.0 [] 30514 smcpp.analysis.base DEBUG Q: -683657.7 [] 30514 smcpp.optimize.optimizers DEBUG x: -5.897, 2.092, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 30847 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 30847 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 30848 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 30848 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 30866 smcpp.model DEBUG r1:8.989052 r2:7.059363 30867 smcpp.analysis.base DEBUG reg: 12.0 [] 30867 smcpp.analysis.base DEBUG Q: -683657.6 [] 30867 smcpp.optimize.optimizers DEBUG x: -5.897, 1.777, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 31199 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 31200 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 31200 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 31200 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 31249 smcpp.model DEBUG r1:8.989052 r2:6.493486 31250 smcpp.analysis.base DEBUG reg: 12.0 [] 31250 smcpp.analysis.base DEBUG Q: -683657.6 [] 31251 smcpp.optimize.optimizers DEBUG x: -5.897, 1.764, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 31581 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 31582 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 31582 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 31582 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 31600 smcpp.model DEBUG r1:8.989052 r2:6.470425 31601 smcpp.analysis.base DEBUG reg: 12.0 [] 31601 smcpp.analysis.base DEBUG Q: -683657.6 [] 31602 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 31932 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 31932 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 31933 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 31933 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 31951 smcpp.model DEBUG r1:8.989052 r2:6.447187 31952 smcpp.analysis.base DEBUG reg: 12.0 [] 31952 smcpp.analysis.base DEBUG Q: -683657.6 [] 31953 smcpp.optimize.optimizers DEBUG x: -5.897, 1.645, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 32284 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 32285 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 32285 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 32286 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 32303 smcpp.model DEBUG r1:8.989052 r2:6.263922 32304 smcpp.analysis.base DEBUG reg: 12.0 [] 32305 smcpp.analysis.base DEBUG Q: -683657.6 [] 32305 smcpp.optimize.optimizers DEBUG x: -5.897, 1.737, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 32637 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 32638 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 32638 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 32639 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 32656 smcpp.model DEBUG r1:8.989052 r2:6.423770 32657 smcpp.analysis.base DEBUG reg: 12.0 [] 32658 smcpp.analysis.base DEBUG Q: -683657.6 [] 32658 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 32988 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 32989 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 32989 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 32989 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 33007 smcpp.model DEBUG r1:8.989052 r2:6.447187 33008 smcpp.analysis.base DEBUG reg: 12.0 [] 33008 smcpp.analysis.base DEBUG Q: -683657.6 [] 33009 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 4.092, 3.092, 3.092, 3.092, 3.092, 3.092 33339 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 33340 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 33340 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 33340 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.8 33358 smcpp.model DEBUG r1:10.988800 r2:6.349582 33359 smcpp.analysis.base DEBUG reg: 14.6 [] 33360 smcpp.analysis.base DEBUG Q: -683660.6 [] 33360 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.474, 3.092, 3.092, 3.092, 3.092, 3.092 33692 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 33692 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 33693 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.0 33693 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 33711 smcpp.model DEBUG r1:9.543017 r2:8.306840 33712 smcpp.analysis.base DEBUG reg: 12.7 [] 33712 smcpp.analysis.base DEBUG Q: -683658.2 [] 33713 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 3.092, 3.092, 3.092, 3.092, 3.092, 3.092 34043 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 34044 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 34044 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 34045 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.4 34062 smcpp.model DEBUG r1:8.989052 r2:6.447187 34063 smcpp.analysis.base DEBUG reg: 12.0 [] 34063 smcpp.analysis.base DEBUG Q: -683657.6 [] 34064 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 2.474, 3.092, 3.092, 3.092, 3.092, 3.092 34394 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 34395 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 34395 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 34395 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 34413 smcpp.model DEBUG r1:8.989052 r2:6.952565 34414 smcpp.analysis.base DEBUG reg: 12.0 [] 34414 smcpp.analysis.base DEBUG Q: -683657.4 [] 34415 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 2.092, 3.092, 3.092, 3.092, 3.092, 3.092 34746 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 34746 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 34747 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 34747 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 34765 smcpp.model DEBUG r1:8.989052 r2:7.403731 34766 smcpp.analysis.base DEBUG reg: 12.0 [] 34766 smcpp.analysis.base DEBUG Q: -683657.4 [] 34766 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.669, 3.092, 3.092, 3.092, 3.092, 3.092 35096 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 35096 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 35097 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.0 35097 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 35114 smcpp.model DEBUG r1:9.152731 r2:8.001781 35115 smcpp.analysis.base DEBUG reg: 12.2 [] 35116 smcpp.analysis.base DEBUG Q: -683657.6 [] 35116 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 2.193, 3.092, 3.092, 3.092, 3.092, 3.092 35447 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 35447 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 35447 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 35448 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.2 35465 smcpp.model DEBUG r1:8.989052 r2:7.274732 35466 smcpp.analysis.base DEBUG reg: 12.0 [] 35467 smcpp.analysis.base DEBUG Q: -683657.4 [] 35467 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.930, 3.092, 3.092, 3.092, 3.092, 3.092 35798 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 35799 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 35799 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 35799 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.1 35817 smcpp.model DEBUG r1:8.989052 r2:7.621095 35818 smcpp.analysis.base DEBUG reg: 12.0 [] 35818 smcpp.analysis.base DEBUG Q: -683657.4 [] 35819 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 3.092, 3.092, 3.092, 3.092, 3.092 36149 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 36150 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 36150 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 36150 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.1 36168 smcpp.model DEBUG r1:8.989052 r2:7.653262 36169 smcpp.analysis.base DEBUG reg: 12.0 [] 36169 smcpp.analysis.base DEBUG Q: -683657.4 [] 36169 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.895, 3.092, 3.092, 3.092, 3.092, 3.092 36500 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 36501 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 36501 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 36501 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.1 36519 smcpp.model DEBUG r1:8.989052 r2:7.669910 36520 smcpp.analysis.base DEBUG reg: 12.0 [] 36520 smcpp.analysis.base DEBUG Q: -683657.4 [] 36521 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 3.092, 3.092, 3.092, 3.092, 3.092 36852 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 36853 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.2 36853 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 36853 smcpp._smcpp DEBUG im(('aro',)).q4: -42543.1 36871 smcpp.model DEBUG r1:8.989052 r2:7.653262 36872 smcpp.analysis.base DEBUG reg: 12.0 [] 36872 smcpp.analysis.base DEBUG Q: -683657.4 [] 36873 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 4.092, 3.092, 3.092, 3.092, 3.092 37204 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 37205 smcpp._smcpp DEBUG im(('aro',)).q2: -636528.9 37205 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.9 37205 smcpp._smcpp DEBUG im(('aro',)).q4: -42553.7 37223 smcpp.model DEBUG r1:10.989052 r2:8.447917 37224 smcpp.analysis.base DEBUG reg: 14.6 [] 37224 smcpp.analysis.base DEBUG Q: -683670.3 [] 37224 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.474, 3.092, 3.092, 3.092, 3.092 37555 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 37556 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.4 37556 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.2 37556 smcpp._smcpp DEBUG im(('aro',)).q4: -42528.4 37574 smcpp.model DEBUG r1:9.855653 r2:7.955269 37575 smcpp.analysis.base DEBUG reg: 13.1 [] 37575 smcpp.analysis.base DEBUG Q: -683644.4 [] 37576 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 0.135, 3.092, 3.092, 3.092, 3.092 37909 smcpp._smcpp DEBUG im(('aro',)).q1: -4.3 37909 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.6 37909 smcpp._smcpp DEBUG im(('aro',)).q3: -4571.6 37910 smcpp._smcpp DEBUG im(('aro',)).q4: -42534.9 37927 smcpp.model DEBUG r1:12.533606 r2:9.536424 37928 smcpp.analysis.base DEBUG reg: 16.7 [] 37928 smcpp.analysis.base DEBUG Q: -683657.0 [] 37929 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.474, 3.092, 3.092, 3.092, 3.092 38260 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 38260 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.4 38261 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.2 38261 smcpp._smcpp DEBUG im(('aro',)).q4: -42528.4 38279 smcpp.model DEBUG r1:9.855653 r2:7.955269 38280 smcpp.analysis.base DEBUG reg: 13.1 [] 38280 smcpp.analysis.base DEBUG Q: -683644.4 [] 38280 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 2.092, 3.092, 3.092, 3.092, 3.092 38610 smcpp._smcpp DEBUG im(('aro',)).q1: -4.1 38611 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.4 38611 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.0 38611 smcpp._smcpp DEBUG im(('aro',)).q4: -42532.9 38629 smcpp.model DEBUG r1:8.988978 r2:7.601155 38630 smcpp.analysis.base DEBUG reg: 12.0 [] 38630 smcpp.analysis.base DEBUG Q: -683647.4 [] 38631 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 0.962, 3.092, 3.092, 3.092, 3.092 38962 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 38962 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.5 38963 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.6 38963 smcpp._smcpp DEBUG im(('aro',)).q4: -42527.3 38980 smcpp.model DEBUG r1:10.878540 r2:8.444581 38981 smcpp.analysis.base DEBUG reg: 14.5 [] 38982 smcpp.analysis.base DEBUG Q: -683645.0 [] 38982 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.336, 3.092, 3.092, 3.092, 3.092 39313 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 39313 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.5 39314 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.3 39314 smcpp._smcpp DEBUG im(('aro',)).q4: -42527.8 39331 smcpp.model DEBUG r1:10.130484 r2:8.070564 39332 smcpp.analysis.base DEBUG reg: 13.5 [] 39333 smcpp.analysis.base DEBUG Q: -683644.2 [] 39333 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, 3.092, 3.092, 3.092, 3.092 39665 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 39665 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.5 39665 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.3 39666 smcpp._smcpp DEBUG im(('aro',)).q4: -42527.8 39683 smcpp.model DEBUG r1:10.165593 r2:8.086183 39684 smcpp.analysis.base DEBUG reg: 13.5 [] 39685 smcpp.analysis.base DEBUG Q: -683644.2 [] 39685 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.301, 3.092, 3.092, 3.092, 3.092 40017 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 40018 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.5 40018 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.3 40018 smcpp._smcpp DEBUG im(('aro',)).q4: -42527.7 40036 smcpp.model DEBUG r1:10.201054 r2:8.102160 40037 smcpp.analysis.base DEBUG reg: 13.6 [] 40037 smcpp.analysis.base DEBUG Q: -683644.2 [] 40038 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, 3.092, 3.092, 3.092, 3.092 40368 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 40369 smcpp._smcpp DEBUG im(('aro',)).q2: -636529.5 40369 smcpp._smcpp DEBUG im(('aro',)).q3: -4569.3 40369 smcpp._smcpp DEBUG im(('aro',)).q4: -42527.8 40387 smcpp.model DEBUG r1:10.165593 r2:8.086183 40388 smcpp.analysis.base DEBUG reg: 13.5 [] 40388 smcpp.analysis.base DEBUG Q: -683644.2 [] 40389 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, 4.092, 3.092, 3.092, 3.092 40721 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 40721 smcpp._smcpp DEBUG im(('aro',)).q2: -636471.3 40722 smcpp._smcpp DEBUG im(('aro',)).q3: -4568.8 40722 smcpp._smcpp DEBUG im(('aro',)).q4: -42940.0 40740 smcpp.model DEBUG r1:12.165593 r2:9.121560 40741 smcpp.analysis.base DEBUG reg: 16.2 [] 40741 smcpp.analysis.base DEBUG Q: -684000.5 [] 40742 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, 1.474, 3.092, 3.092, 3.092 41074 smcpp._smcpp DEBUG im(('aro',)).q1: -4.2 41074 smcpp._smcpp DEBUG im(('aro',)).q2: -636589.3 41075 smcpp._smcpp DEBUG im(('aro',)).q3: -4572.1 41075 smcpp._smcpp DEBUG im(('aro',)).q4: -41812.5 41093 smcpp.model DEBUG r1:10.165024 r2:7.872423 41093 smcpp.analysis.base DEBUG reg: 13.5 [] 41094 smcpp.analysis.base DEBUG Q: -682991.6 [] 41094 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -1.144, 3.092, 3.092, 3.092 41433 smcpp._smcpp DEBUG im(('aro',)).q1: -6.3 41433 smcpp._smcpp DEBUG im(('aro',)).q2: -636746.0 41434 smcpp._smcpp DEBUG im(('aro',)).q3: -4735.9 41434 smcpp._smcpp DEBUG im(('aro',)).q4: -41225.2 41452 smcpp.model DEBUG r1:15.091227 r2:11.090377 41453 smcpp.analysis.base DEBUG reg: 20.1 [] 41453 smcpp.analysis.base DEBUG Q: -682733.4 [] 41453 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.521, 3.092, 3.092, 3.092 41786 smcpp._smcpp DEBUG im(('aro',)).q1: -5.1 41786 smcpp._smcpp DEBUG im(('aro',)).q2: -636668.0 41787 smcpp._smcpp DEBUG im(('aro',)).q3: -4634.8 41787 smcpp._smcpp DEBUG im(('aro',)).q4: -41189.7 41805 smcpp.model DEBUG r1:13.843792 r2:10.049649 41806 smcpp.analysis.base DEBUG reg: 18.4 [] 41806 smcpp.analysis.base DEBUG Q: -682516.1 [] 41806 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.521, 3.092, 3.092, 3.092 42140 smcpp._smcpp DEBUG im(('aro',)).q1: -5.1 42141 smcpp._smcpp DEBUG im(('aro',)).q2: -636668.0 42141 smcpp._smcpp DEBUG im(('aro',)).q3: -4634.8 42141 smcpp._smcpp DEBUG im(('aro',)).q4: -41189.7 42159 smcpp.model DEBUG r1:13.843792 r2:10.049649 42160 smcpp.analysis.base DEBUG reg: 18.4 [] 42160 smcpp.analysis.base DEBUG Q: -682516.1 [] 42161 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, 0.241, 3.092, 3.092, 3.092 42494 smcpp._smcpp DEBUG im(('aro',)).q1: -4.5 42494 smcpp._smcpp DEBUG im(('aro',)).q2: -636624.1 42495 smcpp._smcpp DEBUG im(('aro',)).q3: -4588.6 42495 smcpp._smcpp DEBUG im(('aro',)).q4: -41347.3 42513 smcpp.model DEBUG r1:12.320270 r2:8.969810 42514 smcpp.analysis.base DEBUG reg: 16.4 [] 42514 smcpp.analysis.base DEBUG Q: -682580.8 [] 42514 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.230, 3.092, 3.092, 3.092 42847 smcpp._smcpp DEBUG im(('aro',)).q1: -4.8 42847 smcpp._smcpp DEBUG im(('aro',)).q2: -636647.1 42848 smcpp._smcpp DEBUG im(('aro',)).q3: -4610.6 42848 smcpp._smcpp DEBUG im(('aro',)).q4: -41229.3 42865 smcpp.model DEBUG r1:13.261858 r2:9.608784 42866 smcpp.analysis.base DEBUG reg: 17.7 [] 42867 smcpp.analysis.base DEBUG Q: -682509.4 [] 42867 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 3.092, 3.092, 3.092 43199 smcpp._smcpp DEBUG im(('aro',)).q1: -4.9 43200 smcpp._smcpp DEBUG im(('aro',)).q2: -636653.2 43200 smcpp._smcpp DEBUG im(('aro',)).q3: -4617.4 43200 smcpp._smcpp DEBUG im(('aro',)).q4: -41213.2 43218 smcpp.model DEBUG r1:13.452461 r2:9.749640 43219 smcpp.analysis.base DEBUG reg: 17.9 [] 43219 smcpp.analysis.base DEBUG Q: -682506.6 [] 43220 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.359, 3.092, 3.092, 3.092 43551 smcpp._smcpp DEBUG im(('aro',)).q1: -5.0 43552 smcpp._smcpp DEBUG im(('aro',)).q2: -636655.6 43552 smcpp._smcpp DEBUG im(('aro',)).q3: -4620.0 43553 smcpp._smcpp DEBUG im(('aro',)).q4: -41208.1 43570 smcpp.model DEBUG r1:13.520795 r2:9.801000 43571 smcpp.analysis.base DEBUG reg: 18.0 [] 43572 smcpp.analysis.base DEBUG Q: -682506.7 [] 43572 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.291, 3.092, 3.092, 3.092 43903 smcpp._smcpp DEBUG im(('aro',)).q1: -4.9 43904 smcpp._smcpp DEBUG im(('aro',)).q2: -636650.9 43904 smcpp._smcpp DEBUG im(('aro',)).q3: -4614.8 43905 smcpp._smcpp DEBUG im(('aro',)).q4: -41218.6 43922 smcpp.model DEBUG r1:13.384127 r2:9.698731 43924 smcpp.analysis.base DEBUG reg: 17.8 [] 43924 smcpp.analysis.base DEBUG Q: -682507.1 [] 43925 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 3.092, 3.092, 3.092 44257 smcpp._smcpp DEBUG im(('aro',)).q1: -4.9 44258 smcpp._smcpp DEBUG im(('aro',)).q2: -636653.2 44258 smcpp._smcpp DEBUG im(('aro',)).q3: -4617.4 44258 smcpp._smcpp DEBUG im(('aro',)).q4: -41213.2 44276 smcpp.model DEBUG r1:13.452461 r2:9.749640 44277 smcpp.analysis.base DEBUG reg: 17.9 [] 44277 smcpp.analysis.base DEBUG Q: -682506.6 [] 44278 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 4.092, 3.092, 3.092 44609 smcpp._smcpp DEBUG im(('aro',)).q1: -4.9 44610 smcpp._smcpp DEBUG im(('aro',)).q2: -637068.6 44611 smcpp._smcpp DEBUG im(('aro',)).q3: -4612.1 44611 smcpp._smcpp DEBUG im(('aro',)).q4: -41933.1 44629 smcpp.model DEBUG r1:15.452075 r2:11.173180 44629 smcpp.analysis.base DEBUG reg: 20.6 [] 44630 smcpp.analysis.base DEBUG Q: -683639.3 [] 44630 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 1.473, 3.092, 3.092 44965 smcpp._smcpp DEBUG im(('aro',)).q1: -5.3 44965 smcpp._smcpp DEBUG im(('aro',)).q2: -636383.9 44966 smcpp._smcpp DEBUG im(('aro',)).q3: -4647.7 44966 smcpp._smcpp DEBUG im(('aro',)).q4: -40136.1 44984 smcpp.model DEBUG r1:13.452461 r2:8.501742 44985 smcpp.analysis.base DEBUG reg: 17.9 [] 44985 smcpp.analysis.base DEBUG Q: -681190.9 [] 44986 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, -1.048, 3.092, 3.092 45315 smcpp._smcpp DEBUG im(('aro',)).q1: -12.2 45315 smcpp._smcpp DEBUG im(('aro',)).q2: -635908.5 45315 smcpp._smcpp DEBUG im(('aro',)).q3: -5038.1 45316 smcpp._smcpp DEBUG im(('aro',)).q4: -42322.3 45333 smcpp.model DEBUG r1:14.899377 r2:9.971045 45334 smcpp.analysis.base DEBUG reg: 19.8 [] 45334 smcpp.analysis.base DEBUG Q: -683301.0 [] 45335 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 1.473, 3.092, 3.092 45667 smcpp._smcpp DEBUG im(('aro',)).q1: -5.3 45667 smcpp._smcpp DEBUG im(('aro',)).q2: -636383.9 45668 smcpp._smcpp DEBUG im(('aro',)).q3: -4647.7 45668 smcpp._smcpp DEBUG im(('aro',)).q4: -40136.1 45686 smcpp.model DEBUG r1:13.452461 r2:8.501742 45686 smcpp.analysis.base DEBUG reg: 17.9 [] 45687 smcpp.analysis.base DEBUG Q: -681190.9 [] 45687 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.510, 3.092, 3.092 46021 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 46021 smcpp._smcpp DEBUG im(('aro',)).q2: -636232.6 46022 smcpp._smcpp DEBUG im(('aro',)).q3: -4714.0 46022 smcpp._smcpp DEBUG im(('aro',)).q4: -39921.8 46040 smcpp.model DEBUG r1:13.452461 r2:8.581329 46041 smcpp.analysis.base DEBUG reg: 17.9 [] 46041 smcpp.analysis.base DEBUG Q: -680892.5 [] 46041 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, -0.085, 3.092, 3.092 46375 smcpp._smcpp DEBUG im(('aro',)).q1: -7.5 46375 smcpp._smcpp DEBUG im(('aro',)).q2: -636096.8 46376 smcpp._smcpp DEBUG im(('aro',)).q3: -4801.7 46376 smcpp._smcpp DEBUG im(('aro',)).q4: -40219.1 46393 smcpp.model DEBUG r1:13.452461 r2:8.946876 46394 smcpp.analysis.base DEBUG reg: 17.9 [] 46395 smcpp.analysis.base DEBUG Q: -681143.0 [] 46395 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.661, 3.092, 3.092 46730 smcpp._smcpp DEBUG im(('aro',)).q1: -6.0 46730 smcpp._smcpp DEBUG im(('aro',)).q2: -636261.3 46731 smcpp._smcpp DEBUG im(('aro',)).q3: -4698.6 46731 smcpp._smcpp DEBUG im(('aro',)).q4: -39910.3 46748 smcpp.model DEBUG r1:13.452461 r2:8.525794 46749 smcpp.analysis.base DEBUG reg: 17.9 [] 46750 smcpp.analysis.base DEBUG Q: -680894.1 [] 46750 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 3.092, 3.092 47088 smcpp._smcpp DEBUG im(('aro',)).q1: -6.1 47088 smcpp._smcpp DEBUG im(('aro',)).q2: -636245.5 47088 smcpp._smcpp DEBUG im(('aro',)).q3: -4707.0 47089 smcpp._smcpp DEBUG im(('aro',)).q4: -39914.1 47107 smcpp.model DEBUG r1:13.452461 r2:8.555022 47108 smcpp.analysis.base DEBUG reg: 17.9 [] 47108 smcpp.analysis.base DEBUG Q: -680890.5 [] 47108 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.551, 3.092, 3.092 47444 smcpp._smcpp DEBUG im(('aro',)).q1: -6.1 47444 smcpp._smcpp DEBUG im(('aro',)).q2: -636240.7 47445 smcpp._smcpp DEBUG im(('aro',)).q3: -4709.6 47445 smcpp._smcpp DEBUG im(('aro',)).q4: -39916.5 47462 smcpp.model DEBUG r1:13.452461 r2:8.564637 47463 smcpp.analysis.base DEBUG reg: 17.9 [] 47464 smcpp.analysis.base DEBUG Q: -680890.8 [] 47464 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.602, 3.092, 3.092 47799 smcpp._smcpp DEBUG im(('aro',)).q1: -6.0 47800 smcpp._smcpp DEBUG im(('aro',)).q2: -636250.3 47800 smcpp._smcpp DEBUG im(('aro',)).q3: -4704.4 47800 smcpp._smcpp DEBUG im(('aro',)).q4: -39912.3 47818 smcpp.model DEBUG r1:13.452461 r2:8.545839 47819 smcpp.analysis.base DEBUG reg: 17.9 [] 47819 smcpp.analysis.base DEBUG Q: -680890.9 [] 47820 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 3.092, 3.092 48156 smcpp._smcpp DEBUG im(('aro',)).q1: -6.1 48157 smcpp._smcpp DEBUG im(('aro',)).q2: -636245.5 48157 smcpp._smcpp DEBUG im(('aro',)).q3: -4707.0 48157 smcpp._smcpp DEBUG im(('aro',)).q4: -39914.1 48175 smcpp.model DEBUG r1:13.452461 r2:8.555022 48176 smcpp.analysis.base DEBUG reg: 17.9 [] 48176 smcpp.analysis.base DEBUG Q: -680890.5 [] 48177 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 4.092, 3.092 48511 smcpp._smcpp DEBUG im(('aro',)).q1: -5.8 48512 smcpp._smcpp DEBUG im(('aro',)).q2: -636281.7 48512 smcpp._smcpp DEBUG im(('aro',)).q3: -4692.6 48512 smcpp._smcpp DEBUG im(('aro',)).q4: -40359.3 48530 smcpp.model DEBUG r1:15.452461 r2:9.564337 48531 smcpp.analysis.base DEBUG reg: 20.6 [] 48531 smcpp.analysis.base DEBUG Q: -681360.0 [] 48532 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 1.474, 3.092 48865 smcpp._smcpp DEBUG im(('aro',)).q1: -7.8 48865 smcpp._smcpp DEBUG im(('aro',)).q2: -636426.9 48866 smcpp._smcpp DEBUG im(('aro',)).q3: -4794.1 48866 smcpp._smcpp DEBUG im(('aro',)).q4: -40698.9 48884 smcpp.model DEBUG r1:13.452241 r2:8.048471 48885 smcpp.analysis.base DEBUG reg: 17.9 [] 48885 smcpp.analysis.base DEBUG Q: -681945.6 [] 48885 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 3.092, 3.092 49220 smcpp._smcpp DEBUG im(('aro',)).q1: -6.1 49220 smcpp._smcpp DEBUG im(('aro',)).q2: -636245.5 49221 smcpp._smcpp DEBUG im(('aro',)).q3: -4707.0 49221 smcpp._smcpp DEBUG im(('aro',)).q4: -39914.1 49239 smcpp.model DEBUG r1:13.452461 r2:8.555022 49240 smcpp.analysis.base DEBUG reg: 17.9 [] 49240 smcpp.analysis.base DEBUG Q: -680890.5 [] 49241 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.474, 3.092 49575 smcpp._smcpp DEBUG im(('aro',)).q1: -6.4 49576 smcpp._smcpp DEBUG im(('aro',)).q2: -636281.7 49576 smcpp._smcpp DEBUG im(('aro',)).q3: -4725.9 49576 smcpp._smcpp DEBUG im(('aro',)).q4: -39865.0 49594 smcpp.model DEBUG r1:13.452241 r2:8.178368 49596 smcpp.analysis.base DEBUG reg: 17.9 [] 49596 smcpp.analysis.base DEBUG Q: -680896.9 [] 49596 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 3.474, 3.092 49930 smcpp._smcpp DEBUG im(('aro',)).q1: -6.0 49930 smcpp._smcpp DEBUG im(('aro',)).q2: -636240.8 49931 smcpp._smcpp DEBUG im(('aro',)).q3: -4699.8 49931 smcpp._smcpp DEBUG im(('aro',)).q4: -40053.7 49949 smcpp.model DEBUG r1:14.216393 r2:8.887829 49950 smcpp.analysis.base DEBUG reg: 18.9 [] 49950 smcpp.analysis.base DEBUG Q: -681019.2 [] 49951 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.798, 3.092 50287 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 50288 smcpp._smcpp DEBUG im(('aro',)).q2: -636258.9 50288 smcpp._smcpp DEBUG im(('aro',)).q3: -4714.6 50288 smcpp._smcpp DEBUG im(('aro',)).q4: -39856.2 50306 smcpp.model DEBUG r1:13.452241 r2:8.349393 50307 smcpp.analysis.base DEBUG reg: 17.9 [] 50308 smcpp.analysis.base DEBUG Q: -680853.8 [] 50308 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.795, 3.092 50671 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 50672 smcpp._smcpp DEBUG im(('aro',)).q2: -636259.1 50672 smcpp._smcpp DEBUG im(('aro',)).q3: -4714.6 50673 smcpp._smcpp DEBUG im(('aro',)).q4: -39855.9 50690 smcpp.model DEBUG r1:13.452241 r2:8.347572 50691 smcpp.analysis.base DEBUG reg: 17.9 [] 50692 smcpp.analysis.base DEBUG Q: -680853.8 [] 50692 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 3.092 51027 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 51027 smcpp._smcpp DEBUG im(('aro',)).q2: -636260.0 51028 smcpp._smcpp DEBUG im(('aro',)).q3: -4715.1 51028 smcpp._smcpp DEBUG im(('aro',)).q4: -39854.5 51046 smcpp.model DEBUG r1:13.452241 r2:8.338244 51047 smcpp.analysis.base DEBUG reg: 17.9 [] 51047 smcpp.analysis.base DEBUG Q: -680853.7 [] 51048 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.663, 3.092 51383 smcpp._smcpp DEBUG im(('aro',)).q1: -6.3 51383 smcpp._smcpp DEBUG im(('aro',)).q2: -636267.4 51384 smcpp._smcpp DEBUG im(('aro',)).q3: -4718.8 51384 smcpp._smcpp DEBUG im(('aro',)).q4: -39849.3 51401 smcpp.model DEBUG r1:13.452241 r2:8.270874 51402 smcpp.analysis.base DEBUG reg: 17.9 [] 51403 smcpp.analysis.base DEBUG Q: -680859.8 [] 51403 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.783, 3.092 51738 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 51739 smcpp._smcpp DEBUG im(('aro',)).q2: -636259.8 51739 smcpp._smcpp DEBUG im(('aro',)).q3: -4715.0 51740 smcpp._smcpp DEBUG im(('aro',)).q4: -39854.8 51757 smcpp.model DEBUG r1:13.452241 r2:8.340151 51758 smcpp.analysis.base DEBUG reg: 17.9 [] 51758 smcpp.analysis.base DEBUG Q: -680853.7 [] 51759 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.776, 3.092 52094 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 52094 smcpp._smcpp DEBUG im(('aro',)).q2: -636260.2 52094 smcpp._smcpp DEBUG im(('aro',)).q3: -4715.2 52095 smcpp._smcpp DEBUG im(('aro',)).q4: -39854.2 52113 smcpp.model DEBUG r1:13.452241 r2:8.336344 52114 smcpp.analysis.base DEBUG reg: 17.9 [] 52114 smcpp.analysis.base DEBUG Q: -680853.7 [] 52115 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 3.092 52449 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 52450 smcpp._smcpp DEBUG im(('aro',)).q2: -636260.0 52450 smcpp._smcpp DEBUG im(('aro',)).q3: -4715.1 52450 smcpp._smcpp DEBUG im(('aro',)).q4: -39854.5 52468 smcpp.model DEBUG r1:13.452241 r2:8.338244 52469 smcpp.analysis.base DEBUG reg: 17.9 [] 52469 smcpp.analysis.base DEBUG Q: -680853.7 [] 52469 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 4.092 52804 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 52804 smcpp._smcpp DEBUG im(('aro',)).q2: -816637.2 52805 smcpp._smcpp DEBUG im(('aro',)).q3: -4612.0 52805 smcpp._smcpp DEBUG im(('aro',)).q4: -39884.0 52822 smcpp.model DEBUG r1:14.452241 r2:8.169762 52823 smcpp.analysis.base DEBUG reg: 19.2 [] 52824 smcpp.analysis.base DEBUG Q: -861158.7 [] 52824 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 1.474 53158 smcpp._smcpp DEBUG im(('aro',)).q1: -6.4 53159 smcpp._smcpp DEBUG im(('aro',)).q2: -703618.9 53159 smcpp._smcpp DEBUG im(('aro',)).q3: -4987.2 53159 smcpp._smcpp DEBUG im(('aro',)).q4: -39840.0 53177 smcpp.model DEBUG r1:14.445926 r2:8.846617 53178 smcpp.analysis.base DEBUG reg: 19.2 [] 53178 smcpp.analysis.base DEBUG Q: -748471.7 [] 53179 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 3.092 53513 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 53513 smcpp._smcpp DEBUG im(('aro',)).q2: -636260.0 53514 smcpp._smcpp DEBUG im(('aro',)).q3: -4715.1 53514 smcpp._smcpp DEBUG im(('aro',)).q4: -39854.5 53531 smcpp.model DEBUG r1:13.452241 r2:8.338244 53532 smcpp.analysis.base DEBUG reg: 17.9 [] 53533 smcpp.analysis.base DEBUG Q: -680853.7 [] 53533 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.474 53869 smcpp._smcpp DEBUG im(('aro',)).q1: -6.3 53869 smcpp._smcpp DEBUG im(('aro',)).q2: -642752.6 53870 smcpp._smcpp DEBUG im(('aro',)).q3: -4828.3 53870 smcpp._smcpp DEBUG im(('aro',)).q4: -39830.0 53887 smcpp.model DEBUG r1:13.445926 r2:8.499721 53888 smcpp.analysis.base DEBUG reg: 17.9 [] 53889 smcpp.analysis.base DEBUG Q: -687435.1 [] 53889 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 3.474 54223 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 54223 smcpp._smcpp DEBUG im(('aro',)).q2: -665767.3 54224 smcpp._smcpp DEBUG im(('aro',)).q3: -4655.1 54224 smcpp._smcpp DEBUG im(('aro',)).q4: -39867.9 54241 smcpp.model DEBUG r1:13.834207 r2:8.260017 54242 smcpp.analysis.base DEBUG reg: 18.4 [] 54243 smcpp.analysis.base DEBUG Q: -710314.8 [] 54243 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.843 54578 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 54578 smcpp._smcpp DEBUG im(('aro',)).q2: -632963.9 54579 smcpp._smcpp DEBUG im(('aro',)).q3: -4759.8 54579 smcpp._smcpp DEBUG im(('aro',)).q4: -39844.9 54597 smcpp.model DEBUG r1:13.203881 r2:8.398043 54598 smcpp.analysis.base DEBUG reg: 17.6 [] 54598 smcpp.analysis.base DEBUG Q: -677592.4 [] 54599 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.865 54933 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 54933 smcpp._smcpp DEBUG im(('aro',)).q2: -632871.9 54933 smcpp._smcpp DEBUG im(('aro',)).q3: -4755.8 54934 smcpp._smcpp DEBUG im(('aro',)).q4: -39845.7 54951 smcpp.model DEBUG r1:13.225994 r2:8.392438 54952 smcpp.analysis.base DEBUG reg: 17.6 [] 54952 smcpp.analysis.base DEBUG Q: -677497.2 [] 54953 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.882 55287 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 55288 smcpp._smcpp DEBUG im(('aro',)).q2: -632847.5 55288 smcpp._smcpp DEBUG im(('aro',)).q3: -4752.7 55289 smcpp._smcpp DEBUG im(('aro',)).q4: -39846.4 55306 smcpp.model DEBUG r1:13.242865 r2:8.388198 55307 smcpp.analysis.base DEBUG reg: 17.6 [] 55307 smcpp.analysis.base DEBUG Q: -677470.4 [] 55308 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.885 55642 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 55642 smcpp._smcpp DEBUG im(('aro',)).q2: -632847.4 55643 smcpp._smcpp DEBUG im(('aro',)).q3: -4752.1 55643 smcpp._smcpp DEBUG im(('aro',)).q4: -39846.5 55660 smcpp.model DEBUG r1:13.245836 r2:8.387455 55661 smcpp.analysis.base DEBUG reg: 17.6 [] 55662 smcpp.analysis.base DEBUG Q: -677469.9 [] 55662 smcpp.optimize.optimizers DEBUG x: -5.897, 1.751, 1.907, 1.319, -0.325, 0.577, 2.779, 2.887 55996 smcpp._smcpp DEBUG im(('aro',)).q1: -6.2 55996 smcpp._smcpp DEBUG im(('aro',)).q2: -632848.0 55997 smcpp._smcpp DEBUG im(('aro',)).q3: -4751.7 55997 smcpp._smcpp DEBUG im(('aro',)).q4: -39846.6 56014 smcpp.model DEBUG r1:13.247901 r2:8.386939 56015 smcpp.analysis.base DEBUG reg: 17.6 [] 56015 smcpp.analysis.base DEBUG Q: -677470.3 [] 56016 smcpp.optimize.optimizers DEBUG x: -14.885, 0.410, 0.723, -0.454, -3.742, -1.938, 2.467, 2.679