diff --git a/components/raftstore/src/engine_store_ffi/observer.rs b/components/raftstore/src/engine_store_ffi/observer.rs
index dd174612973..9c47050b601 100644
--- a/components/raftstore/src/engine_store_ffi/observer.rs
+++ b/components/raftstore/src/engine_store_ffi/observer.rs
@@ -5,6 +5,7 @@ use std::sync::{mpsc, Arc, Mutex};
 use collections::HashMap;
 use engine_tiflash::FsStatsExt;
 use kvproto::raft_cmdpb::{AdminCmdType, AdminRequest};
+use raft::{eraftpb, StateRole};
 use sst_importer::SstImporter;
 use tikv_util::{debug, error};
 use yatp::{
@@ -144,10 +145,10 @@ impl TiFlashObserver {
         //     TIFLASH_OBSERVER_PRIORITY,
         //     BoxApplySnapshotObserver::new(self.clone()),
         // );
-        // coprocessor_host.registry.register_region_change_observer(
-        //     TIFLASH_OBSERVER_PRIORITY,
-        //     BoxRegionChangeObserver::new(self.clone()),
-        // );
+        coprocessor_host.registry.register_region_change_observer(
+            TIFLASH_OBSERVER_PRIORITY,
+            BoxRegionChangeObserver::new(self.clone()),
+        );
         // coprocessor_host.registry.register_pd_task_observer(
         //     TIFLASH_OBSERVER_PRIORITY,
         //     BoxPdTaskObserver::new(self.clone()),
@@ -219,3 +220,17 @@ impl QueryObserver for TiFlashObserver {
         );
     }
 }
+
+impl RegionChangeObserver for TiFlashObserver {
+    fn on_region_changed(
+        &self,
+        ob_ctx: &mut ObserverContext<'_>,
+        e: RegionChangeEvent,
+        _: StateRole,
+    ) {
+        if e == RegionChangeEvent::Destroy {
+            self.engine_store_server_helper
+                .handle_destroy(ob_ctx.region().get_id());
+        }
+    }
+}
diff --git a/components/raftstore/src/store/fsm/peer.rs b/components/raftstore/src/store/fsm/peer.rs
index 0b51b84ad1f..ea3f610b162 100644
--- a/components/raftstore/src/store/fsm/peer.rs
+++ b/components/raftstore/src/store/fsm/peer.rs
@@ -3258,14 +3258,6 @@ where
                 .unsafe_recovery_maybe_finish_wait_apply(/*force=*/ true);
         }
 
-        {
-            let engine_store_server_helper =
-                crate::engine_store_ffi::gen_engine_store_server_helper(
-                    self.ctx.cfg.engine_store_server_helper,
-                );
-            engine_store_server_helper.handle_destroy(region_id);
-        }
-
         let mut meta = self.ctx.store_meta.lock().unwrap();
 
         if meta.atomic_snap_regions.contains_key(&self.region_id()) {
diff --git a/tests/proxy/normal.rs b/tests/proxy/normal.rs
index 9cb6e85004b..cffdd9a6e82 100644
--- a/tests/proxy/normal.rs
+++ b/tests/proxy/normal.rs
@@ -306,3 +306,60 @@ fn test_empty_cmd() {
 
     cluster.shutdown();
 }
+
+#[test]
+fn test_handle_destroy() {
+    let (mut cluster, pd_client) = new_mock_cluster(0, 3);
+
+    // Disable raft log gc in this test case.
+    cluster.cfg.raft_store.raft_log_gc_tick_interval = ReadableDuration::secs(60);
+
+    // Disable default max peer count check.
+    pd_client.disable_default_operator();
+
+    cluster.run();
+    cluster.must_put(b"k1", b"v1");
+    let eng_ids = cluster
+        .engines
+        .iter()
+        .map(|e| e.0.to_owned())
+        .collect::<Vec<_>>();
+
+    let region = cluster.get_region(b"k1");
+    let region_id = region.get_id();
+    let peer_1 = find_peer(&region, eng_ids[0]).cloned().unwrap();
+    let peer_2 = find_peer(&region, eng_ids[1]).cloned().unwrap();
+    cluster.must_transfer_leader(region_id, peer_1);
+
+    iter_ffi_helpers(
+        &cluster,
+        Some(vec![eng_ids[1]]),
+        &mut |_, _, ffi: &mut FFIHelperSet| {
+            let server = &ffi.engine_store_server;
+            assert!(server.kvstore.contains_key(&region_id));
+        },
+    );
+
+    pd_client.must_remove_peer(region_id, peer_2);
+
+    check_key(
+        &cluster,
+        b"k1",
+        b"k2",
+        Some(false),
+        None,
+        Some(vec![eng_ids[1]]),
+    );
+
+    // Region removed in server.
+    iter_ffi_helpers(
+        &cluster,
+        Some(vec![eng_ids[1]]),
+        &mut |_, _, ffi: &mut FFIHelperSet| {
+            let server = &ffi.engine_store_server;
+            assert!(!server.kvstore.contains_key(&region_id));
+        },
+    );
+
+    cluster.shutdown();
+}