diff --git a/doc/source/whatsnew/v2.1.0.rst b/doc/source/whatsnew/v2.1.0.rst
index e24ff67974cd8..18054e0b01191 100644
--- a/doc/source/whatsnew/v2.1.0.rst
+++ b/doc/source/whatsnew/v2.1.0.rst
@@ -548,6 +548,13 @@ Other Deprecations
 - Deprecated :meth:`.Styler.applymap`. Use the new :meth:`.Styler.map` method instead (:issue:`52708`)
 - Deprecated :meth:`DataFrame.applymap`. Use the new :meth:`DataFrame.map` method instead (:issue:`52353`)
 - Deprecated :meth:`DataFrame.swapaxes` and :meth:`Series.swapaxes`, use :meth:`DataFrame.transpose` or :meth:`Series.transpose` instead (:issue:`51946`)
+- Deprecated ``freq`` parameter in :class:`.PeriodArray` constructor, pass ``dtype`` instead (:issue:`52462`)
+- Deprecated allowing non-standard inputs in :func:`take`, pass either a ``numpy.ndarray``, :class:`.ExtensionArray`, :class:`Index`, or :class:`Series` (:issue:`52981`)
+- Deprecated allowing non-standard sequences for :func:`isin`, :func:`value_counts`, :func:`unique`, :func:`factorize`, case to one of ``numpy.ndarray``, :class:`Index`, :class:`.ExtensionArray`, or :class:`Series` before calling (:issue:`52986`)
+- Deprecated behavior of :class:`DataFrame` reductions ``sum``, ``prod``, ``std``, ``var``, ``sem`` with ``axis=None``, in a future version this will operate over both axes returning a scalar instead of behaving like ``axis=0``; note this also affects numpy functions e.g. ``np.sum(df)`` (:issue:`21597`)
+- Deprecated behavior of :func:`concat` when :class:`DataFrame` has columns that are all-NA, in a future version these will not be discarded when determining the resulting dtype (:issue:`40893`)
+- Deprecated behavior of :meth:`Series.dt.to_pydatetime`, in a future version this will return a :class:`Series` containing python ``datetime`` objects instead of an ``ndarray`` of datetimes; this matches the behavior of other :attr:`Series.dt` properties (:issue:`20306`)
+- Deprecated logical operations (``|``, ``&``, ``^``) between pandas objects and dtype-less sequences (e.g. ``list``, ``tuple``), wrap a sequence in a :class:`Series` or NumPy array before operating instead (:issue:`51521`)
 - Deprecated parameter ``convert_type`` in :meth:`Series.apply` (:issue:`52140`)
 - Deprecated passing a dictionary to :meth:`.SeriesGroupBy.agg`; pass a list of aggregations instead (:issue:`50684`)
 - Deprecated the ``fastpath`` keyword in :class:`Categorical` constructor, use :meth:`Categorical.from_codes` instead (:issue:`20110`)