diff --git a/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts b/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
index b4b229f66f..4bf503e6c4 100644
--- a/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
+++ b/plugins/node/opentelemetry-instrumentation-redis-4/src/instrumentation.ts
@@ -175,6 +175,15 @@ export class RedisInstrumentation extends InstrumentationBase<any> {
           this._getPatchRedisClientMulti()
         );
 
+        if (isWrapped(redisClientPrototype?.MULTI)) {
+          this._unwrap(redisClientPrototype, 'MULTI');
+        }
+        this._wrap(
+          redisClientPrototype,
+          'MULTI',
+          this._getPatchRedisClientMulti()
+        );
+
         if (isWrapped(redisClientPrototype?.sendCommand)) {
           this._unwrap(redisClientPrototype, 'sendCommand');
         }
@@ -198,6 +207,9 @@ export class RedisInstrumentation extends InstrumentationBase<any> {
         if (isWrapped(redisClientPrototype?.multi)) {
           this._unwrap(redisClientPrototype, 'multi');
         }
+        if (isWrapped(redisClientPrototype?.MULTI)) {
+          this._unwrap(redisClientPrototype, 'MULTI');
+        }
         if (isWrapped(redisClientPrototype?.sendCommand)) {
           this._unwrap(redisClientPrototype, 'sendCommand');
         }