diff --git a/.eslintrc.js b/.eslintrc.js
index 7574e1b4b6c7f7..28a31d050a6de1 100644
--- a/.eslintrc.js
+++ b/.eslintrc.js
@@ -329,5 +329,7 @@ module.exports = {
     TextDecoder: 'readable',
     queueMicrotask: 'readable',
     globalThis: 'readable',
+    btoa: 'readable',
+    atob: 'readable',
   },
 };
diff --git a/doc/api/globals.md b/doc/api/globals.md
index 6f8c9d3b398c11..f3cb382460dd9d 100644
--- a/doc/api/globals.md
+++ b/doc/api/globals.md
@@ -146,6 +146,20 @@ This variable may appear to be global but is not. See [`__dirname`][].
 
 This variable may appear to be global but is not. See [`__filename`][].
 
+## `atob(data)`
+<!-- YAML
+added: REPLACEME
+-->
+
+Global alias for [`buffer.atob()`][].
+
+## `btoa(data)`
+<!-- YAML
+added: REPLACEME
+-->
+
+Global alias for [`buffer.btoa()`][].
+
 ## `clearImmediate(immediateObject)`
 <!-- YAML
 added: v0.9.1
@@ -402,6 +416,8 @@ The object that acts as the namespace for all W3C
 [`URL`]: url.md#url_class_url
 [`__dirname`]: modules.md#modules_dirname
 [`__filename`]: modules.md#modules_filename
+[`buffer.atob()`]: buffer.html#buffer_buffer_atob_data
+[`buffer.btoa()`]: buffer.html#buffer_buffer_btoa_data
 [`clearImmediate`]: timers.md#timers_clearimmediate_immediate
 [`clearInterval`]: timers.md#timers_clearinterval_timeout
 [`clearTimeout`]: timers.md#timers_cleartimeout_timeout
diff --git a/lib/internal/bootstrap/node.js b/lib/internal/bootstrap/node.js
index 260670a20226cb..d8f5c18d12d79b 100644
--- a/lib/internal/bootstrap/node.js
+++ b/lib/internal/bootstrap/node.js
@@ -42,6 +42,7 @@ const {
   FunctionPrototypeCall,
   JSONParse,
   ObjectDefineProperty,
+  ObjectDefineProperties,
   ObjectGetPrototypeOf,
   ObjectPreventExtensions,
   ObjectSetPrototypeOf,
@@ -400,7 +401,11 @@ function setupGlobalProxy() {
 }
 
 function setupBuffer() {
-  const { Buffer } = require('buffer');
+  const {
+    Buffer,
+    atob,
+    btoa,
+  } = require('buffer');
   const bufferBinding = internalBinding('buffer');
 
   // Only after this point can C++ use Buffer::New()
@@ -408,11 +413,25 @@ function setupBuffer() {
   delete bufferBinding.setBufferPrototype;
   delete bufferBinding.zeroFill;
 
-  ObjectDefineProperty(global, 'Buffer', {
-    value: Buffer,
-    enumerable: false,
-    writable: true,
-    configurable: true
+  ObjectDefineProperties(global, {
+    'Buffer': {
+      value: Buffer,
+      enumerable: false,
+      writable: true,
+      configurable: true,
+    },
+    'atob': {
+      value: atob,
+      enumerable: false,
+      writable: true,
+      configurable: true,
+    },
+    'btoa': {
+      value: btoa,
+      enumerable: false,
+      writable: true,
+      configurable: true,
+    },
   });
 }
 
diff --git a/test/common/index.js b/test/common/index.js
index 89c4fcaaa99568..5bb3077c53f6ba 100644
--- a/test/common/index.js
+++ b/test/common/index.js
@@ -263,6 +263,8 @@ let knownGlobals = [
   setInterval,
   setTimeout,
   queueMicrotask,
+  atob,
+  btoa,
 ];
 
 // TODO(@jasnell): This check can be temporary. AbortController is
diff --git a/test/parallel/test-btoa-atob-global.js b/test/parallel/test-btoa-atob-global.js
new file mode 100644
index 00000000000000..06a6d3ed28f3f1
--- /dev/null
+++ b/test/parallel/test-btoa-atob-global.js
@@ -0,0 +1,9 @@
+'use strict';
+
+require('../common');
+
+const { strictEqual } = require('assert');
+const buffer = require('buffer');
+
+strictEqual(globalThis.atob, buffer.atob);
+strictEqual(globalThis.btoa, buffer.btoa);