Error when I use SAVER with size.factor =1

[ScarletChieftain]

Hi,
I have a dataset with 22164 rows and 268 columns. When I run SAVER with size.factor = 1 since my dataset has been normalized, an Error appears. It said:

Error in optimize(calc.loglik.b, interval = c(0, var(y/sf)/mean(y/sf)), :
'xmin' not less than 'xmax'
In addition: Warning message:
In if (!(grepl("matrix", class(x), ignore.case = TRUE))) { :
the condition has length > 1 and only the first element will be used

And my device is M1 macbook, running R 4.1.0.
This error does not appear when I use default size.factor.

Thanks!

[ScarletChieftain]

And I used as.matrix()

[mohuangx]

Hi there,
Can you try setting the size.factor = rep(1, ncol(x))?

[mohuangx]

Ah actually, never mind. There's a function that automatically does that.

Are there any negative numbers in your dataset?