diff --git a/.reek.yml b/.reek.yml
index c3df9fbcd..b164fd4f4 100644
--- a/.reek.yml
+++ b/.reek.yml
@@ -51,6 +51,7 @@ detectors:
       - SidekiqUniqueJobs::Logging#debug_item
       - SidekiqUniqueJobs::NotUniqueWorker#initialize
       - SidekiqUniqueJobs::OnConflict::Reject#push_to_deadset
+      - SidekiqUniqueJobs::Orphans::Reaper#active?
       - SidekiqUniqueJobs::Orphans::Reaper#entries
       - SidekiqUniqueJobs::SidekiqWorkerMethods#worker_class_constantize
       - SidekiqUniqueJobs::Web::Helpers#cparams
@@ -90,6 +91,7 @@ detectors:
       - SidekiqUniqueJobs::Locksmith#create_lock
       - SidekiqUniqueJobs::Middleware#self.configure_client
       - SidekiqUniqueJobs::Middleware#self.configure_server
+      - SidekiqUniqueJobs::Orphans::Reaper#active?
       - SidekiqUniqueJobs::Orphans::Reaper#enqueued?
       - SidekiqUniqueJobs::UpgradeLocks#keys_for_digest
   RepeatedConditional:
@@ -124,6 +126,7 @@ detectors:
       - SidekiqUniqueJobs::Middleware#call
       - SidekiqUniqueJobs::Middleware#self.configure_server
       - SidekiqUniqueJobs::Orphans::Manager#start
+      - SidekiqUniqueJobs::Orphans::Reaper#active?
       - SidekiqUniqueJobs::Orphans::Reaper#enqueued?
       - SidekiqUniqueJobs::Orphans::Reaper#entries
       - SidekiqUniqueJobs::Profiler#self.stop
@@ -144,6 +147,7 @@ detectors:
       - SidekiqUniqueJobs::Lock::BaseLock
       - SidekiqUniqueJobs::Locksmith
       - SidekiqUniqueJobs::Lock
+      - SidekiqUniqueJobs::Orphans::Reaper
   UncommunicativeVariableName:
     exclude:
       - Hash#slice
diff --git a/lib/sidekiq_unique_jobs/lock_digest.rb b/lib/sidekiq_unique_jobs/lock_digest.rb
index 8940fa8ac..b587c6adb 100644
--- a/lib/sidekiq_unique_jobs/lock_digest.rb
+++ b/lib/sidekiq_unique_jobs/lock_digest.rb
@@ -1,6 +1,6 @@
 # frozen_string_literal: true
 
-require 'openssl'
+require "openssl"
 
 module SidekiqUniqueJobs
   # Handles uniqueness of sidekiq arguments
diff --git a/lib/sidekiq_unique_jobs/lua/reap_orphans.lua b/lib/sidekiq_unique_jobs/lua/reap_orphans.lua
index 38cbf9011..db1cbb095 100644
--- a/lib/sidekiq_unique_jobs/lua/reap_orphans.lua
+++ b/lib/sidekiq_unique_jobs/lua/reap_orphans.lua
@@ -23,6 +23,7 @@ local redisversion = ARGV[6]
 <%= include_partial "shared/_common.lua" %>
 <%= include_partial "shared/_find_digest_in_queues.lua" %>
 <%= include_partial "shared/_find_digest_in_sorted_set.lua" %>
+<%= include_partial "shared/_find_digest_in_process_set.lua" %>
 ----------  END local functions ----------
 
 
@@ -61,6 +62,16 @@ repeat
       end
     end
 
+    -- TODO: Add check for jobs checked out by process
+    if found ~= true then
+      log_debug("Searching for digest:", digest, "in process sets")
+      local queue = find_digest_in_process_set(digest)
+      if queue then
+        log_debug("found digest:", digest, "in queue:", queue)
+        found = true
+      end
+    end
+
     if found ~= true then
       local queued     = digest .. ":QUEUED"
       local primed     = digest .. ":PRIMED"
diff --git a/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_process_set.lua b/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_process_set.lua
new file mode 100644
index 000000000..3c79b7c1a
--- /dev/null
+++ b/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_process_set.lua
@@ -0,0 +1,35 @@
+local function find_digest_in_process_set(digest)
+  local process_cursor = 0
+  local job_cursor     = 0
+  local pattern        = "*" .. digest .. "*"
+  local found          = false
+
+  log_debug("searching in list processes:",
+            "for digest:", digest,
+            "cursor:", process_cursor)
+
+  repeat
+    local process_paginator   = redis.call("SSCAN", "processes", process_cursor, "MATCH", "*")
+    local next_process_cursor = process_paginator[1]
+    local processes           = process_paginator[2]
+    log_debug("Found number of processes:", #processes, "next cursor:", next_process_cursor)
+
+    for _, process in ipairs(processes) do
+      log_debug("searching in process set:", process,
+                "for digest:", digest,
+                "cursor:", process_cursor)
+
+      local job = redis.call("HGET", process, "info")
+
+      if string.find(job, digest) then
+        log_debug("Found digest", digest, "in process:", process)
+        found = true
+        break
+      end
+    end
+
+    process_cursor = next_process_cursor
+  until found == true or process_cursor == "0"
+
+  return found
+end
diff --git a/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_queues.lua b/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_queues.lua
index 2a07bfe24..6486e3bf3 100644
--- a/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_queues.lua
+++ b/lib/sidekiq_unique_jobs/lua/shared/_find_digest_in_queues.lua
@@ -6,7 +6,7 @@ local function find_digest_in_queues(digest)
 
   repeat
     log_debug("searching all queues for a matching digest:", digest)
-    local pagination  = redis.call("SCAN", cursor, "MATCH", "*queue:*", "COUNT", count)
+    local pagination  = redis.call("SCAN", cursor, "MATCH", "queue:*", "COUNT", count)
     local next_cursor = pagination[1]
     local queues      = pagination[2]
 
diff --git a/lib/sidekiq_unique_jobs/orphans/reaper.rb b/lib/sidekiq_unique_jobs/orphans/reaper.rb
index 6a7cdd944..25578981b 100644
--- a/lib/sidekiq_unique_jobs/orphans/reaper.rb
+++ b/lib/sidekiq_unique_jobs/orphans/reaper.rb
@@ -9,10 +9,12 @@ module Orphans
     #
     # @author Mikael Henriksson <mikael@zoolutions.se>
     #
+    # rubocop:disable Metrics/ClassLength
     class Reaper
       include SidekiqUniqueJobs::Connection
       include SidekiqUniqueJobs::Script::Caller
       include SidekiqUniqueJobs::Logging
+      include SidekiqUniqueJobs::JSON
 
       #
       # Execute deletion of orphaned digests
@@ -141,7 +143,7 @@ def orphans
       # @return [false] when no job was found for this digest
       #
       def belongs_to_job?(digest)
-        scheduled?(digest) || retried?(digest) || enqueued?(digest)
+        scheduled?(digest) || retried?(digest) || enqueued?(digest) || active?(digest)
       end
 
       #
@@ -185,6 +187,20 @@ def enqueued?(digest)
         end
       end
 
+      def active?(digest)
+        Sidekiq.redis do |conn|
+          procs = conn.sscan_each("processes").to_a.sort
+
+          result = conn.pipelined do
+            procs.map do |key|
+              conn.hget(key, "info")
+            end
+          end
+
+          result.flatten.compact.any? { |job| load_json(job)[LOCK_DIGEST] == digest }
+        end
+      end
+
       #
       # Loops through all the redis queues and yields them one by one
       #
@@ -233,5 +249,6 @@ def in_sorted_set?(key, digest)
         conn.zscan_each(key, match: "*#{digest}*", count: 1).to_a.any?
       end
     end
+    # rubocop:enable Metrics/ClassLength
   end
 end
diff --git a/lib/sidekiq_unique_jobs/web.rb b/lib/sidekiq_unique_jobs/web.rb
index 08d75868d..16e7377c6 100644
--- a/lib/sidekiq_unique_jobs/web.rb
+++ b/lib/sidekiq_unique_jobs/web.rb
@@ -2,7 +2,7 @@
 
 begin
   require "sidekiq/web"
-rescue LoadError # rubocop:disable Lint/SuppressedException
+rescue LoadError
   # client-only usage
 end
 
diff --git a/spec/sidekiq_unique_jobs/lua/reap_orphans_spec.rb b/spec/sidekiq_unique_jobs/lua/reap_orphans_spec.rb
index e3aa763a7..e233fe337 100644
--- a/spec/sidekiq_unique_jobs/lua/reap_orphans_spec.rb
+++ b/spec/sidekiq_unique_jobs/lua/reap_orphans_spec.rb
@@ -101,4 +101,33 @@
       end
     end
   end
+
+  context "when digest exists in a a process set" do
+    context "without job" do
+      it "keeps the digest" do
+        expect { reap_orphans }.to change { digests.count }.by(-1)
+        expect(unique_keys).to match_array([])
+      end
+    end
+
+    context "with job" do
+      let(:process_key) { "worker-id" }
+
+      before do
+        SidekiqUniqueJobs.redis do |conn|
+          conn.multi do
+            conn.sadd("processes", process_key)
+            conn.exists(process_key)
+            conn.hmset(process_key, "info", Sidekiq.dump_json(item), "busy", 1, "beat", Time.now.to_f, "quiet", false)
+            conn.expire(process_key, 60)
+          end
+        end
+      end
+
+      it "keeps the digest" do
+        expect { reap_orphans }.not_to change { digests.count }.from(1)
+        expect(unique_keys).not_to match_array([])
+      end
+    end
+  end
 end
diff --git a/spec/sidekiq_unique_jobs/orphans/reaper_spec.rb b/spec/sidekiq_unique_jobs/orphans/reaper_spec.rb
index 87d751062..298ff5ddb 100644
--- a/spec/sidekiq_unique_jobs/orphans/reaper_spec.rb
+++ b/spec/sidekiq_unique_jobs/orphans/reaper_spec.rb
@@ -140,6 +140,35 @@
           end
         end
       end
+
+      context "when processing" do
+        context "without job in process" do
+          it "deletes the digest" do
+            expect { call }.to change { digests.count }.by(-1)
+            expect(unique_keys).to match_array([])
+          end
+        end
+
+        context "with job in process" do
+          let(:process_key) { "worker-id" }
+
+          before do
+            SidekiqUniqueJobs.redis do |conn|
+              conn.multi do
+                conn.sadd("processes", process_key)
+                conn.exists(process_key)
+                conn.hmset(process_key, "info", Sidekiq.dump_json(item), "busy", 1, "beat", Time.now.to_f, "quiet", false)
+                conn.expire(process_key, 60)
+              end
+            end
+          end
+
+          it "keeps the digest" do
+            expect { call }.not_to change { digests.count }.from(1)
+            expect(unique_keys).not_to match_array([])
+          end
+        end
+      end
     end
 
     context "when config.reaper = :ruby" do
diff --git a/spec/support/rspec_benchmark.rb b/spec/support/rspec_benchmark.rb
index f4dbed2b6..61a0c7b6d 100644
--- a/spec/support/rspec_benchmark.rb
+++ b/spec/support/rspec_benchmark.rb
@@ -11,6 +11,6 @@
   RSpec::Benchmark.configure do |config|
     config.samples = 10
   end
-rescue LoadError # rubocop:disable Lint/SuppressedException
+rescue LoadError
   # Do nothing, we don't have test_prof
 end
diff --git a/spec/support/test_prof.rb b/spec/support/test_prof.rb
index 66eceb6f9..21800af93 100644
--- a/spec/support/test_prof.rb
+++ b/spec/support/test_prof.rb
@@ -13,6 +13,6 @@
     # color output
     config.color = true
   end
-rescue LoadError # rubocop:disable Lint/SuppressedException
+rescue LoadError
   # Do nothing, we don't have test_prof
 end