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DESCRIPTION
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DESCRIPTION
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Package: benchdamic
Type: Package
Title: Benchmark of differential abundance methods on microbiome data
Version: 1.13.2
Authors@R:
c(person(given = "Matteo",
family = "Calgaro",
email = "[email protected]",
role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-3056-518X")),
person(given = "Chiara",
family = "Romualdi",
role = c("aut"),
comment = c(ORCID = "0000-0003-4792-9047")),
person(given = "Davide",
family = "Risso",
email = "[email protected]",
role = c("aut"),
comment = c(ORCID = "0000-0001-8508-5012")),
person(given = "Nicola",
family = "Vitulo",
role = c("aut"),
comment = c(ORCID = "0000-0002-9571-0747")))
Description: Starting from a microbiome dataset (16S or WMS with absolute count
values) it is possible to perform several analysis to assess the
performances of many differential abundance detection methods. A basic and
standardized version of the main differential abundance analysis methods is
supplied but the user can also add his method to the benchmark.
The analyses focus on 4 main aspects: i) the goodness of fit of each
method's distributional assumptions on the observed count data, ii) the
ability to control the false discovery rate, iii) the within and between
method concordances, iv) the truthfulness of the findings if any apriori
knowledge is given. Several graphical functions are available for result
visualization.
License: Artistic-2.0
Encoding: UTF-8
Depends: R (>= 4.3.0)
Imports: stats,
stats4,
utils,
methods,
phyloseq,
TreeSummarizedExperiment,
BiocParallel,
zinbwave,
edgeR,
DESeq2,
limma,
ALDEx2,
corncob,
SummarizedExperiment,
MAST,
Seurat,
ANCOMBC,
microbiome,
mixOmics,
lme4,
NOISeq,
dearseq,
MicrobiomeStat,
Maaslin2,
GUniFrac,
metagenomeSeq,
MGLM,
ggplot2,
RColorBrewer,
plyr,
reshape2,
ggdendro,
ggridges,
graphics,
cowplot,
grDevices,
tidytext
Suggests: knitr,
rmarkdown,
kableExtra,
BiocStyle,
magick,
SPsimSeq,
testthat
VignetteBuilder: knitr
LazyData: TRUE
RoxygenNote: 7.3.2
biocViews: Metagenomics,
Microbiome,
DifferentialExpression,
MultipleComparison,
Normalization,
Preprocessing,
Software
BugReports: https://github.com/mcalgaro93/benchdamic/issues