diff --git a/.github/workflows/release-artifacts.yml b/.github/workflows/release-artifacts.yml
index 0601a7dbaf15..3575e5fad9cb 100644
--- a/.github/workflows/release-artifacts.yml
+++ b/.github/workflows/release-artifacts.yml
@@ -99,7 +99,7 @@ jobs:
     runs-on: ${{ matrix.os }}
     strategy:
       matrix:
-        os: [ubuntu-20.04, macos-11]
+        os: [ubuntu-22.04, macos-11]
         arch: [x86_64, aarch64]
         # is_pr is a flag used to exclude certain jobs from the matrix on PRs.
         # It is not read by the rest of the workflow.
@@ -139,10 +139,6 @@ jobs:
         if: matrix.arch == 'aarch64'
         run: echo 'CIBW_ARCHS_LINUX=aarch64' >> $GITHUB_ENV
 
-      - name: Only build a single wheel on PR
-        if: startsWith(github.ref, 'refs/pull/')
-        run: echo "CIBW_BUILD="cp37-manylinux_${{ matrix.arch }}"" >> $GITHUB_ENV
-
       - name: Build wheels
         run: python -m cibuildwheel --output-dir wheelhouse
         env:
diff --git a/changelog.d/14798.misc b/changelog.d/14798.misc
new file mode 100644
index 000000000000..de4fdeb8dac9
--- /dev/null
+++ b/changelog.d/14798.misc
@@ -0,0 +1 @@
+Bump Ubuntu from 20.04 to 22.04 when building Synapse Python wheels in CI.
\ No newline at end of file