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I have a question about make custom gene set. I read the custom gene set.
Step2 --snp-loc ${magma_dir}/g1000_eur.bim ,1kg SNPs are used.
But before I read the issue,I use the SNPs in the GWAS summary data to annotate gene,and then using the output file to Step3.
I follow (#2) to get gene set. And I find the these 2 output gene.out files are different.
Maybe Step2 --snp-loc should use SNPs in GWAS summary?
Thanks in advanced!
# Step 2: make gene annotation file for MAGMA using the following command, this only needs to be done# once for different GWAS summary statistics, and the file will be saved to out/step1.genes.annot
mkdir -p out/step1
${magma_dir}/magma \
--annotate window=10,10 \
--snp-loc ${magma_dir}/g1000_eur.bim \
--gene-loc ${magma_dir}/NCBI37.3.gene.loc \
--out out/step1
The text was updated successfully, but these errors were encountered:
Dear @KangchengHou ,
Thanks for your great tool!
I have a question about make custom gene set. I read the custom gene set.
Step2 --snp-loc ${magma_dir}/g1000_eur.bim ,1kg SNPs are used.
But before I read the issue,I use the SNPs in the GWAS summary data to annotate gene,and then using the output file to Step3.
I follow (#2) to get gene set. And I find the these 2 output gene.out files are different.
Maybe Step2 --snp-loc should use SNPs in GWAS summary?
Thanks in advanced!
The text was updated successfully, but these errors were encountered: