diff --git a/x-pack/plugins/security_solution/public/common/components/endpoint/__snapshots__/page_view.test.tsx.snap b/x-pack/plugins/security_solution/public/common/components/endpoint/__snapshots__/page_view.test.tsx.snap
index 5d077dba447fa..6d8ea6b346eff 100644
--- a/x-pack/plugins/security_solution/public/common/components/endpoint/__snapshots__/page_view.test.tsx.snap
+++ b/x-pack/plugins/security_solution/public/common/components/endpoint/__snapshots__/page_view.test.tsx.snap
@@ -2,11 +2,11 @@
 
 exports[`PageView component should display body header custom element 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -97,11 +97,11 @@ exports[`PageView component should display body header custom element 1`] = `
 
 exports[`PageView component should display body header wrapped in EuiTitle 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -195,11 +195,11 @@ exports[`PageView component should display body header wrapped in EuiTitle 1`] =
 
 exports[`PageView component should display header left and right 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -308,11 +308,11 @@ exports[`PageView component should display header left and right 1`] = `
 
 exports[`PageView component should display only body if not header props used 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -380,11 +380,11 @@ exports[`PageView component should display only body if not header props used 1`
 
 exports[`PageView component should display only header left 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -482,11 +482,11 @@ exports[`PageView component should display only header left 1`] = `
 
 exports[`PageView component should display only header right but include an empty left side 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -581,11 +581,11 @@ exports[`PageView component should display only header right but include an empt
 
 exports[`PageView component should pass through EuiPage props 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
@@ -670,11 +670,11 @@ exports[`PageView component should pass through EuiPage props 1`] = `
 
 exports[`PageView component should use custom element for header left and not wrap in EuiTitle 1`] = `
 .c0.endpoint--isListView {
-  padding: 0;
+  padding: 0 70px 0 24px;
 }
 
 .c0.endpoint--isListView .endpoint-header {
-  padding: 24px;
+  padding: 24px 0;
   margin-bottom: 0;
 }
 
diff --git a/x-pack/plugins/security_solution/public/common/components/endpoint/page_view.tsx b/x-pack/plugins/security_solution/public/common/components/endpoint/page_view.tsx
index 6fe15310fc88e..65c536fe12085 100644
--- a/x-pack/plugins/security_solution/public/common/components/endpoint/page_view.tsx
+++ b/x-pack/plugins/security_solution/public/common/components/endpoint/page_view.tsx
@@ -21,13 +21,14 @@ import {
 import React, { memo, MouseEventHandler, ReactNode, useMemo } from 'react';
 import styled from 'styled-components';
 import { EuiTabProps } from '@elastic/eui/src/components/tabs/tab';
+import { gutterTimeline } from '../../lib/helpers';
 
 const StyledEuiPage = styled(EuiPage)`
   &.endpoint--isListView {
-    padding: 0;
+    padding: 0 ${gutterTimeline} 0 ${(props) => props.theme.eui.euiSizeL};
 
     .endpoint-header {
-      padding: ${(props) => props.theme.eui.euiSizeL};
+      padding: ${(props) => props.theme.eui.euiSizeL} 0;
       margin-bottom: 0;
     }
     .endpoint-page-content {
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/action.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/action.ts
index 6866bcbf31f89..e14e39bf45c93 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/action.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/action.ts
@@ -6,6 +6,7 @@
 
 import { PolicyData } from '../../../../../../common/endpoint/types';
 import { ServerApiError } from '../../../../../common/types';
+import { GetAgentStatusResponse } from '../../../../../../../ingest_manager/common/types/rest_spec';
 
 interface ServerReturnedPolicyListData {
   type: 'serverReturnedPolicyListData';
@@ -22,4 +23,42 @@ interface ServerFailedToReturnPolicyListData {
   payload: ServerApiError;
 }
 
-export type PolicyListAction = ServerReturnedPolicyListData | ServerFailedToReturnPolicyListData;
+interface UserClickedPolicyListDeleteButton {
+  type: 'userClickedPolicyListDeleteButton';
+  payload: { policyId: string };
+}
+
+interface UserOpenedPolicyListDeleteModal {
+  type: 'userOpenedPolicyListDeleteModal';
+  payload: { agentConfigId: string };
+}
+
+interface ServerDeletedPolicyFailure {
+  type: 'serverDeletedPolicyFailure';
+  payload: ServerApiError;
+}
+
+interface ServerDeletedPolicy {
+  type: 'serverDeletedPolicy';
+  payload: { id: string; success: boolean };
+}
+
+interface ServerReturnedPolicyAgentsSummaryForDeleteFailure {
+  type: 'serverReturnedPolicyAgentsSummaryForDeleteFailure';
+  payload: ServerApiError;
+}
+
+interface ServerReturnedPolicyAgentsSummaryForDelete {
+  type: 'serverReturnedPolicyAgentsSummaryForDelete';
+  payload: { agentStatusSummary: GetAgentStatusResponse['results'] };
+}
+
+export type PolicyListAction =
+  | ServerReturnedPolicyListData
+  | ServerFailedToReturnPolicyListData
+  | UserClickedPolicyListDeleteButton
+  | ServerDeletedPolicyFailure
+  | ServerDeletedPolicy
+  | UserOpenedPolicyListDeleteModal
+  | ServerReturnedPolicyAgentsSummaryForDeleteFailure
+  | ServerReturnedPolicyAgentsSummaryForDelete;
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/index.test.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/index.test.ts
index a312134bbcd22..ce81c58893a7b 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/index.test.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/index.test.ts
@@ -13,7 +13,12 @@ import { DATASOURCE_SAVED_OBJECT_TYPE } from '../../../../../../../ingest_manage
 import { policyListReducer } from './reducer';
 import { policyListMiddlewareFactory } from './middleware';
 
-import { isOnPolicyListPage, selectIsLoading, urlSearchParams } from './selectors';
+import {
+  isOnPolicyListPage,
+  selectIsLoading,
+  urlSearchParams,
+  selectIsDeleting,
+} from './selectors';
 import { DepsStartMock, depsStartMock } from '../../../../../common/mock/endpoint';
 import { setPolicyListApiMockImplementation } from './test_mock_utils';
 import { INGEST_API_DATASOURCES } from './services/ingest';
@@ -85,6 +90,33 @@ describe('policy list store concerns', () => {
     expect(selectIsLoading(store.getState())).toBe(false);
   });
 
+  it('it sets `isDeleting` when `userClickedPolicyListDeleteButton`', async () => {
+    expect(selectIsDeleting(store.getState())).toBe(false);
+    store.dispatch({
+      type: 'userClickedPolicyListDeleteButton',
+      payload: {
+        policyId: '123',
+      },
+    });
+    expect(selectIsDeleting(store.getState())).toBe(true);
+    await waitForAction('serverDeletedPolicy');
+    expect(selectIsDeleting(store.getState())).toBe(false);
+  });
+
+  it('it sets refreshes policy data when `serverDeletedPolicy`', async () => {
+    expect(selectIsLoading(store.getState())).toBe(false);
+    store.dispatch({
+      type: 'serverDeletedPolicy',
+      payload: {
+        policyId: '',
+        success: true,
+      },
+    });
+    expect(selectIsLoading(store.getState())).toBe(true);
+    await waitForAction('serverReturnedPolicyListData');
+    expect(selectIsLoading(store.getState())).toBe(false);
+  });
+
   it('it resets state on `userChangedUrl` and pathname is NOT `/policy`', async () => {
     store.dispatch({
       type: 'userChangedUrl',
@@ -108,9 +140,18 @@ describe('policy list store concerns', () => {
       location: undefined,
       policyItems: [],
       isLoading: false,
+      isDeleting: false,
+      deleteStatus: undefined,
       pageIndex: 0,
       pageSize: 10,
       total: 0,
+      agentStatusSummary: {
+        error: 0,
+        events: 0,
+        offline: 0,
+        online: 0,
+        total: 0,
+      },
     });
   });
   it('uses default pagination params when not included in url', async () => {
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/middleware.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/middleware.ts
index 66962c378537f..39c685da3ec46 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/middleware.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/middleware.ts
@@ -5,10 +5,19 @@
  */
 
 import { GetPolicyListResponse, PolicyListState } from '../../types';
-import { sendGetEndpointSpecificDatasources } from './services/ingest';
+import {
+  sendGetEndpointSpecificDatasources,
+  sendDeleteDatasource,
+  sendGetFleetAgentStatusForConfig,
+} from './services/ingest';
 import { isOnPolicyListPage, urlSearchParams } from './selectors';
 import { ImmutableMiddlewareFactory } from '../../../../../common/store';
 import { initialPolicyListState } from './reducer';
+import {
+  DeleteDatasourcesResponse,
+  DeleteDatasourcesRequest,
+  GetAgentStatusResponse,
+} from '../../../../../../../ingest_manager/common';
 
 export const policyListMiddlewareFactory: ImmutableMiddlewareFactory<PolicyListState> = (
   coreStart
@@ -19,7 +28,10 @@ export const policyListMiddlewareFactory: ImmutableMiddlewareFactory<PolicyListS
     next(action);
 
     const state = getState();
-    if (action.type === 'userChangedUrl' && isOnPolicyListPage(state)) {
+    if (
+      (action.type === 'userChangedUrl' && isOnPolicyListPage(state)) ||
+      action.type === 'serverDeletedPolicy'
+    ) {
       const { page_index: pageIndex, page_size: pageSize } = urlSearchParams(state);
       let response: GetPolicyListResponse;
 
@@ -47,6 +59,45 @@ export const policyListMiddlewareFactory: ImmutableMiddlewareFactory<PolicyListS
           total: response ? response.total : initialPolicyListState().total,
         },
       });
+    } else if (action.type === 'userClickedPolicyListDeleteButton') {
+      const { policyId } = action.payload;
+      const datasourceIds: DeleteDatasourcesRequest['body']['datasourceIds'] = [policyId];
+      let apiResponse: DeleteDatasourcesResponse;
+      try {
+        apiResponse = await sendDeleteDatasource(http, { body: { datasourceIds } });
+      } catch (err) {
+        dispatch({
+          type: 'serverDeletedPolicyFailure',
+          payload: err.body ?? err,
+        });
+        return;
+      }
+
+      dispatch({
+        type: 'serverDeletedPolicy',
+        payload: {
+          id: apiResponse ? apiResponse[0].id : '',
+          success: true,
+        },
+      });
+    } else if (action.type === 'userOpenedPolicyListDeleteModal') {
+      const { agentConfigId } = action.payload;
+      let apiResponse: GetAgentStatusResponse;
+      try {
+        apiResponse = await sendGetFleetAgentStatusForConfig(http, agentConfigId);
+      } catch (err) {
+        dispatch({
+          type: 'serverReturnedPolicyAgentsSummaryForDeleteFailure',
+          payload: err.body ?? err,
+        });
+        return;
+      }
+      dispatch({
+        type: 'serverReturnedPolicyAgentsSummaryForDelete',
+        payload: {
+          agentStatusSummary: apiResponse.results,
+        },
+      });
     }
   };
 };
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/reducer.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/reducer.ts
index 3e5c70e53ae9b..a8a2ad3e7cc26 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/reducer.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/reducer.ts
@@ -17,11 +17,20 @@ import { PolicyListState } from '../../types';
 export const initialPolicyListState: () => Immutable<PolicyListState> = () => ({
   policyItems: [],
   isLoading: false,
+  isDeleting: false,
+  deleteStatus: undefined,
   apiError: undefined,
   pageIndex: 0,
   pageSize: 10,
   total: 0,
   location: undefined,
+  agentStatusSummary: {
+    error: 0,
+    events: 0,
+    offline: 0,
+    online: 0,
+    total: 0,
+  },
 });
 
 export const policyListReducer: ImmutableReducer<PolicyListState, AppAction> = (
@@ -33,6 +42,7 @@ export const policyListReducer: ImmutableReducer<PolicyListState, AppAction> = (
       ...state,
       ...action.payload,
       isLoading: false,
+      isDeleting: false,
     };
   }
 
@@ -41,6 +51,47 @@ export const policyListReducer: ImmutableReducer<PolicyListState, AppAction> = (
       ...state,
       apiError: action.payload,
       isLoading: false,
+      isDeleting: false,
+    };
+  }
+
+  if (action.type === 'serverDeletedPolicyFailure') {
+    return {
+      ...state,
+      ...action.payload,
+      isLoading: false,
+      isDeleting: false,
+    };
+  }
+
+  if (action.type === 'serverDeletedPolicy') {
+    return {
+      ...state,
+      deleteStatus: action.payload.success,
+      isLoading: true,
+      isDeleting: false,
+    };
+  }
+
+  if (action.type === 'userClickedPolicyListDeleteButton') {
+    return {
+      ...state,
+      isLoading: false,
+      isDeleting: true,
+    };
+  }
+
+  if (action.type === 'serverReturnedPolicyAgentsSummaryForDelete') {
+    return {
+      ...state,
+      ...action.payload,
+    };
+  }
+
+  if (action.type === 'serverReturnedPolicyAgentsSummaryForDeleteFailure') {
+    return {
+      ...state,
+      ...action.payload,
     };
   }
 
@@ -60,6 +111,7 @@ export const policyListReducer: ImmutableReducer<PolicyListState, AppAction> = (
           ...newState,
           apiError: undefined,
           isLoading: true,
+          isDeleting: false,
         };
       }
       return newState;
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/selectors.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/selectors.ts
index c900ceb186f69..089c97b5520a2 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/selectors.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/selectors.ts
@@ -25,6 +25,13 @@ export const selectIsLoading = (state: Immutable<PolicyListState>) => state.isLo
 
 export const selectApiError = (state: Immutable<PolicyListState>) => state.apiError;
 
+export const selectIsDeleting = (state: Immutable<PolicyListState>) => state.isDeleting;
+
+export const selectDeleteStatus = (state: Immutable<PolicyListState>) => state.deleteStatus;
+
+export const selectAgentStatusSummary = (state: Immutable<PolicyListState>) =>
+  state.agentStatusSummary;
+
 export const isOnPolicyListPage = (state: Immutable<PolicyListState>) => {
   return (
     matchPath(state.location?.pathname ?? '', {
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/services/ingest.ts b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/services/ingest.ts
index db482e2a6bdb6..cece3f1b4c8f2 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/services/ingest.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/store/policy_list/services/ingest.ts
@@ -8,6 +8,8 @@ import { HttpFetchOptions, HttpStart } from 'kibana/public';
 import {
   GetDatasourcesRequest,
   GetAgentStatusResponse,
+  DeleteDatasourcesResponse,
+  DeleteDatasourcesRequest,
   DATASOURCE_SAVED_OBJECT_TYPE,
 } from '../../../../../../../../ingest_manager/common';
 import { GetPolicyListResponse, GetPolicyResponse, UpdatePolicyResponse } from '../../../types';
@@ -17,6 +19,7 @@ const INGEST_API_ROOT = `/api/ingest_manager`;
 export const INGEST_API_DATASOURCES = `${INGEST_API_ROOT}/datasources`;
 const INGEST_API_FLEET = `${INGEST_API_ROOT}/fleet`;
 const INGEST_API_FLEET_AGENT_STATUS = `${INGEST_API_FLEET}/agent-status`;
+const INGEST_API_DELETE_DATASOURCE = `${INGEST_API_DATASOURCES}/delete`;
 
 /**
  * Retrieves a list of endpoint specific datasources (those created with a `package.name` of
@@ -53,6 +56,23 @@ export const sendGetDatasource = (
   return http.get<GetPolicyResponse>(`${INGEST_API_DATASOURCES}/${datasourceId}`, options);
 };
 
+/**
+ * Retrieves a single datasource based on ID from ingest
+ * @param http
+ * @param datasourceId
+ * @param options
+ */
+export const sendDeleteDatasource = (
+  http: HttpStart,
+  body: DeleteDatasourcesRequest,
+  options?: HttpFetchOptions
+) => {
+  return http.post<DeleteDatasourcesResponse>(INGEST_API_DELETE_DATASOURCE, {
+    ...options,
+    body: JSON.stringify(body.body),
+  });
+};
+
 /**
  * Updates a datasources
  *
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/types.ts b/x-pack/plugins/security_solution/public/management/pages/policy/types.ts
index f8cc0d5cd0508..4d798d3717ce4 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/types.ts
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/types.ts
@@ -37,6 +37,12 @@ export interface PolicyListState {
   isLoading: boolean;
   /** current location information */
   location?: Immutable<AppLocation>;
+  /** policy is being deleted */
+  isDeleting: boolean;
+  /** Deletion status */
+  deleteStatus?: boolean;
+  /** A summary of stats for the agents associated with a given Fleet Agent Configuration */
+  agentStatusSummary?: GetAgentStatusResponse['results'];
 }
 
 /**
diff --git a/x-pack/plugins/security_solution/public/management/pages/policy/view/policy_list.tsx b/x-pack/plugins/security_solution/public/management/pages/policy/view/policy_list.tsx
index d34a6d2d93893..24254530f75db 100644
--- a/x-pack/plugins/security_solution/public/management/pages/policy/view/policy_list.tsx
+++ b/x-pack/plugins/security_solution/public/management/pages/policy/view/policy_list.tsx
@@ -17,12 +17,17 @@ import {
   EuiContextMenuItem,
   EuiButtonIcon,
   EuiContextMenuPanel,
+  EuiOverlayMask,
+  EuiConfirmModal,
+  EuiCallOut,
+  EuiSpacer,
 } from '@elastic/eui';
 import { i18n } from '@kbn/i18n';
 import { FormattedMessage } from '@kbn/i18n/react';
 import { useDispatch } from 'react-redux';
 import { useLocation, useHistory } from 'react-router-dom';
 import { createStructuredSelector } from 'reselect';
+import styled from 'styled-components';
 import { CreateStructuredSelector } from '../../../../common/store';
 import * as selectors from '../store/policy_list/selectors';
 import { usePolicyListSelector } from './policy_hooks';
@@ -52,6 +57,10 @@ const NO_WRAP_TRUNCATE_STYLE: CSSProperties = Object.freeze({
   whiteSpace: 'nowrap',
 });
 
+const DangerEuiContextMenuItem = styled(EuiContextMenuItem)`
+  color: ${(props) => props.theme.eui.textColors.danger};
+`;
+
 // eslint-disable-next-line react/display-name
 export const TableRowActions = React.memo<{ items: EuiContextMenuPanelProps['items'] }>(
   ({ items }) => {
@@ -63,8 +72,10 @@ export const TableRowActions = React.memo<{ items: EuiContextMenuPanelProps['ite
       <EuiPopover
         anchorPosition="downRight"
         panelPaddingSize="none"
+        data-test-subj="policyActions"
         button={
           <EuiButtonIcon
+            data-test-subj="policyActionsButton"
             iconType="boxesHorizontal"
             onClick={handleToggleMenu}
             aria-label={i18n.translate('xpack.securitySolution.endpoint.policyList.actionMenu', {
@@ -75,7 +86,7 @@ export const TableRowActions = React.memo<{ items: EuiContextMenuPanelProps['ite
         isOpen={isOpen}
         closePopover={handleCloseMenu}
       >
-        <EuiContextMenuPanel items={items} />
+        <EuiContextMenuPanel items={items} data-test-subj="policyActionsMenu" />
       </EuiPopover>
     );
   }
@@ -106,6 +117,9 @@ export const PolicyList = React.memo(() => {
   const history = useHistory();
   const location = useLocation();
 
+  const [showDelete, setShowDelete] = useState<boolean>(false);
+  const [policyIdToDelete, setPolicyIdToDelete] = useState<string>('');
+
   const dispatch = useDispatch<(action: PolicyListAction) => void>();
   const {
     selectPolicyItems: policyItems,
@@ -114,6 +128,9 @@ export const PolicyList = React.memo(() => {
     selectTotal: totalItemCount,
     selectIsLoading: loading,
     selectApiError: apiError,
+    selectIsDeleting: isDeleting,
+    selectDeleteStatus: deleteStatus,
+    selectAgentStatusSummary: agentStatusSummary,
   } = usePolicyListSelector(selector);
 
   useEffect(() => {
@@ -126,6 +143,38 @@ export const PolicyList = React.memo(() => {
     }
   }, [apiError, dispatch, notifications.toasts]);
 
+  // Handle showing update statuses
+  useEffect(() => {
+    if (deleteStatus !== undefined) {
+      if (deleteStatus === true) {
+        setPolicyIdToDelete('');
+        setShowDelete(false);
+        notifications.toasts.success({
+          toastLifeTimeMs: 10000,
+          title: i18n.translate('xpack.securitySolution.endpoint.policyList.deleteSuccessToast', {
+            defaultMessage: 'Success!',
+          }),
+          body: (
+            <FormattedMessage
+              id="xpack.securitySolution.endpoint.policyList.deleteSuccessToastDetails"
+              defaultMessage="Policy has been deleted."
+            />
+          ),
+        });
+      } else {
+        notifications.toasts.danger({
+          toastLifeTimeMs: 10000,
+          title: i18n.translate('xpack.securitySolution.endpoint.policyList.deleteFailedToast', {
+            defaultMessage: 'Failed!',
+          }),
+          body: i18n.translate('xpack.securitySolution.endpoint.policyList.deleteFailedToastBody', {
+            defaultMessage: 'Failed to delete policy',
+          }),
+        });
+      }
+    }
+  }, [notifications.toasts, deleteStatus]);
+
   const paginationSetup = useMemo(() => {
     return {
       pageIndex,
@@ -143,6 +192,36 @@ export const PolicyList = React.memo(() => {
     [history, location.pathname]
   );
 
+  const handleDeleteOnClick = useCallback(
+    ({ policyId, agentConfigId }: { policyId: string; agentConfigId: string }) => {
+      dispatch({
+        type: 'userOpenedPolicyListDeleteModal',
+        payload: {
+          agentConfigId,
+        },
+      });
+      setPolicyIdToDelete(policyId);
+      setShowDelete(true);
+    },
+    [dispatch]
+  );
+
+  const handleDeleteConfirmation = useCallback(
+    ({ policyId }: { policyId: string }) => {
+      dispatch({
+        type: 'userClickedPolicyListDeleteButton',
+        payload: {
+          policyId,
+        },
+      });
+    },
+    [dispatch]
+  );
+
+  const handleDeleteCancel = useCallback(() => {
+    setShowDelete(false);
+  }, []);
+
   const columns: Array<EuiTableFieldDataColumnType<Immutable<PolicyData>>> = useMemo(
     () => [
       {
@@ -248,6 +327,19 @@ export const PolicyList = React.memo(() => {
                         />
                       </LinkToApp>
                     </EuiContextMenuItem>,
+                    <DangerEuiContextMenuItem
+                      data-test-subj="policyDeleteButton"
+                      icon="trash"
+                      key="policyDeletAction"
+                      onClick={() => {
+                        handleDeleteOnClick({ agentConfigId: item.config_id, policyId: item.id });
+                      }}
+                    >
+                      <FormattedMessage
+                        id="xpack.securitySolution.endpoint.policyList.policyDeleteAction"
+                        defaultMessage="Delete Policy"
+                      />
+                    </DangerEuiContextMenuItem>,
                   ]}
                 />
               );
@@ -256,38 +348,122 @@ export const PolicyList = React.memo(() => {
         ],
       },
     ],
-    [services.application]
+    [services.application, handleDeleteOnClick]
   );
 
   return (
-    <ManagementPageView
-      viewType="list"
-      data-test-subj="policyListPage"
-      headerLeft={i18n.translate('xpack.securitySolution.endpoint.policyList.viewTitle', {
-        defaultMessage: 'Policies',
-      })}
-      bodyHeader={
-        <EuiText color="subdued" data-test-subj="policyTotalCount">
+    <>
+      {showDelete && (
+        <ConfirmDelete
+          hostCount={agentStatusSummary ? agentStatusSummary.total : 0}
+          onCancel={handleDeleteCancel}
+          isDeleting={isDeleting}
+          onConfirm={() => {
+            handleDeleteConfirmation({ policyId: policyIdToDelete });
+          }}
+        />
+      )}
+      <ManagementPageView
+        viewType="list"
+        data-test-subj="policyListPage"
+        headerLeft={i18n.translate('xpack.securitySolution.endpoint.policyList.viewTitle', {
+          defaultMessage: 'Policies',
+        })}
+        bodyHeader={
+          <EuiText color="subdued" data-test-subj="policyTotalCount">
+            <FormattedMessage
+              id="xpack.securitySolution.endpoint.policyList.viewTitleTotalCount"
+              defaultMessage="{totalItemCount, plural, one {# Policy} other {# Policies}}"
+              values={{ totalItemCount }}
+            />
+          </EuiText>
+        }
+      >
+        <EuiBasicTable
+          items={useMemo(() => [...policyItems], [policyItems])}
+          columns={columns}
+          loading={loading}
+          pagination={paginationSetup}
+          onChange={handleTableChange}
+          data-test-subj="policyTable"
+          hasActions={false}
+        />
+        <SpyRoute />
+      </ManagementPageView>
+    </>
+  );
+});
+
+PolicyList.displayName = 'PolicyList';
+
+const ConfirmDelete = React.memo<{
+  hostCount: number;
+  isDeleting: boolean;
+  onConfirm: () => void;
+  onCancel: () => void;
+}>(({ hostCount, isDeleting, onCancel, onConfirm }) => {
+  return (
+    <EuiOverlayMask>
+      <EuiConfirmModal
+        data-test-subj="policyListDeleteModal"
+        title={i18n.translate('xpack.securitySolution.endpoint.policyList.deleteConfirm.title', {
+          defaultMessage: 'Delete policy and deploy changes',
+        })}
+        onCancel={onCancel}
+        onConfirm={onConfirm}
+        buttonColor="danger"
+        confirmButtonText={
+          isDeleting ? (
+            <FormattedMessage
+              id="xpack.securitySolution.endpoint.policyList.deleteConfirm.deletingButton"
+              defaultMessage="Deleting..."
+            />
+          ) : (
+            <FormattedMessage
+              id="xpack.securitySolution.endpoint.policyList.deleteConfirm.confirmDeleteButton"
+              defaultMessage="Delete Policy"
+            />
+          )
+        }
+        confirmButtonDisabled={isDeleting}
+        cancelButtonText={i18n.translate(
+          'xpack.securitySolution.endpoint.policyList.deleteConfirm.cancelButtonTitle',
+          {
+            defaultMessage: 'Cancel',
+          }
+        )}
+      >
+        {hostCount > 0 && (
+          <>
+            <EuiCallOut
+              data-test-subj="policyListWarningCallout"
+              color="danger"
+              title={i18n.translate(
+                'xpack.securitySolution.endpoint.policyList.deleteConfirm.warningTitle',
+                {
+                  defaultMessage:
+                    'This action will delete Endpoint Security from {hostCount, plural, one {# host} other {# hosts}}',
+                  values: { hostCount },
+                }
+              )}
+            >
+              <FormattedMessage
+                id="xpack.securitySolution.endpoint.policyList.deleteConfirm.warningMessage"
+                defaultMessage="Deleting this Policy will remove Endpoint Security from these hosts"
+              />
+            </EuiCallOut>
+            <EuiSpacer size="xl" />
+          </>
+        )}
+        <p>
           <FormattedMessage
-            id="xpack.securitySolution.endpoint.policyList.viewTitleTotalCount"
-            defaultMessage="{totalItemCount, plural, one {# Policy} other {# Policies}}"
-            values={{ totalItemCount }}
+            id="xpack.securitySolution.endpoint.policyList.deleteConfirm.message"
+            defaultMessage="This action cannot be undone. Are you sure you wish to continue?"
           />
-        </EuiText>
-      }
-    >
-      <EuiBasicTable
-        items={useMemo(() => [...policyItems], [policyItems])}
-        columns={columns}
-        loading={loading}
-        pagination={paginationSetup}
-        onChange={handleTableChange}
-        data-test-subj="policyTable"
-        hasActions={false}
-      />
-      <SpyRoute />
-    </ManagementPageView>
+        </p>
+      </EuiConfirmModal>
+    </EuiOverlayMask>
   );
 });
 
-PolicyList.displayName = 'PolicyList';
+ConfirmDelete.displayName = 'ConfirmDelete';
diff --git a/x-pack/test/security_solution_endpoint/apps/endpoint/policy_list.ts b/x-pack/test/security_solution_endpoint/apps/endpoint/policy_list.ts
index a5efd604d63ee..7ce1a07ad5a17 100644
--- a/x-pack/test/security_solution_endpoint/apps/endpoint/policy_list.ts
+++ b/x-pack/test/security_solution_endpoint/apps/endpoint/policy_list.ts
@@ -81,12 +81,24 @@ export default function ({ getPageObjects, getService }: FtrProviderContext) {
           expect(relativeDate).to.match(RELATIVE_DATE_FORMAT);
         });
       });
-      it('should show policy name as link', async () => {
-        const policyNameLink = await testSubjects.find('policyNameLink');
-        expect(await policyNameLink.getTagName()).to.equal('a');
-        expect(await policyNameLink.getAttribute('href')).to.match(
-          new RegExp(`\/management\/policy\/${policyInfo.datasource.id}$`)
+
+      it('should show agent config action as a link', async () => {
+        await (await pageObjects.policy.findFirstActionsButton()).click();
+        const agentConfigLink = await testSubjects.find('agentConfigLink');
+        expect(await agentConfigLink.getAttribute('href')).to.match(
+          new RegExp(`\/ingestManager#\/configs\/${policyInfo.agentConfig.id}$`)
         );
+        // Close action menu
+        await (await pageObjects.policy.findFirstActionsButton()).click();
+      });
+
+      it('should delete a policy', async () => {
+        await pageObjects.policy.launchAndFindDeleteModal();
+        await testSubjects.existOrFail('policyListDeleteModal');
+        await pageObjects.common.clickConfirmOnModal();
+        await pageObjects.endpoint.waitForTableToNotHaveData('policyTable');
+        const policyTotal = await testSubjects.getVisibleText('policyTotalCount');
+        expect(policyTotal).to.equal('0 Policies');
       });
     });
   });
diff --git a/x-pack/test/security_solution_endpoint/page_objects/endpoint_page.ts b/x-pack/test/security_solution_endpoint/page_objects/endpoint_page.ts
index 0f1c9527b717b..830c5ec5a42d1 100644
--- a/x-pack/test/security_solution_endpoint/page_objects/endpoint_page.ts
+++ b/x-pack/test/security_solution_endpoint/page_objects/endpoint_page.ts
@@ -33,6 +33,16 @@ export function EndpointPageProvider({ getService, getPageObjects }: FtrProvider
       });
     },
 
+    async waitForTableToNotHaveData(dataTestSubj: string) {
+      await retry.waitForWithTimeout('table to not have data', 2000, async () => {
+        const tableData = await pageObjects.endpointPageUtils.tableData(dataTestSubj);
+        if (tableData[1][0] === 'No items found') {
+          return true;
+        }
+        return false;
+      });
+    },
+
     async waitForVisibleTextToChange(dataTestSubj: string, currentText: string) {
       await retry.waitForWithTimeout('visible text to change', 2000, async () => {
         const detailFlyoutTitle = await testSubjects.getVisibleText(dataTestSubj);
diff --git a/x-pack/test/security_solution_endpoint/page_objects/policy_page.ts b/x-pack/test/security_solution_endpoint/page_objects/policy_page.ts
index aa9c5361de846..eb481cdfc99c4 100644
--- a/x-pack/test/security_solution_endpoint/page_objects/policy_page.ts
+++ b/x-pack/test/security_solution_endpoint/page_objects/policy_page.ts
@@ -19,6 +19,32 @@ export function EndpointPolicyPageProvider({ getService, getPageObjects }: FtrPr
       await pageObjects.header.waitUntilLoadingHasFinished();
     },
 
+    /**
+     * Finds and returns the Policy Details Page Save button
+     */
+    async findFirstActionsButton() {
+      await this.ensureIsOnPolicyPage();
+      return (await testSubjects.findAll('policyActionsButton'))[0];
+    },
+
+    /**
+     * Finds and returns the Policy Details Page Save button
+     */
+    async launchAndFindDeleteModal() {
+      const actionsButton = await this.findFirstActionsButton();
+      await actionsButton.click();
+      const deleteAction = await testSubjects.find('policyDeleteButton');
+      await deleteAction.click();
+      return await testSubjects.find('policyListDeleteModal');
+    },
+
+    /**
+     * ensures that the Policy Page is the currently display view
+     */
+    async ensureIsOnPolicyPage() {
+      await testSubjects.existOrFail('policyTable');
+    },
+
     /**
      * Navigates to the Endpoint Policy Details page
      *